selected publications
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FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors.
The EMBO journal.
2023
Academic Article
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Times cited: 1 -
EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion.
Cell.
2021
Academic Article
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Times cited: 22 -
ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer.
Nature cancer.
2021
Academic Article
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Times cited: 47 - Loss of the deubiquitinase OTULIN promotes hepatocellular carcinoma (HCC) in an mTOR-dependent manner. Cell death and differentiation. 2020 Editorial Article GET IT
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PHOTACs enable optical control of protein degradation.
Science advances.
2020
Academic Article
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Times cited: 150 -
GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase.
Nature structural & molecular biology.
2019
Academic Article
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Times cited: 38 -
Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs.
Molecular cell.
2019
Academic Article
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Times cited: 58 -
The F-Box Domain-Dependent Activity of EMI1 Regulates PARPi Sensitivity in Triple-Negative Breast Cancers.
Molecular cell.
2018
Academic Article
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Times cited: 49 -
GCL and CUL3 Control the Switch between Cell Lineages by Mediating Localized Degradation of an RTK.
Developmental cell.
2017
Academic Article
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Times cited: 21 -
A Role for the Twins Protein Phosphatase (PP2A-B55) in the Maintenance of Drosophila Genome Integrity.
Genetics.
2016
Academic Article
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Times cited: 18 -
TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response.
Cell reports.
2015
Academic Article
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Times cited: 51 -
Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing.
Nature cell biology.
2014
Academic Article
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Times cited: 58 -
Sugar and chromosome stability: clastogenic effects of sugars in vitamin B6-deficient cells.
PLoS genetics.
2014
Academic Article
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Times cited: 36