selected publications
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Persistence of circulating endothelial microparticles in COPD despite smoking cessation.
Thorax.
2016
Academic Article
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Times cited: 37 -
Progression to COPD in smokers with normal spirometry/low DLCO using different methods to determine normal levels.
The European respiratory journal.
2016
Letter
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Times cited: 3 -
Risk of COPD with obstruction in active smokers with normal spirometry and reduced diffusion capacity.
The European respiratory journal.
2015
Academic Article
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Times cited: 83 -
Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation.
PloS one.
2015
Academic Article
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Times cited: 56 -
Smoking accelerates aging of the small airway epithelium.
Respiratory research.
2014
Academic Article
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Times cited: 57 -
Intraflagellar transport gene expression associated with short cilia in smoking and COPD.
PloS one.
2014
Academic Article
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Times cited: 58 -
High correlation of the response of upper and lower lobe small airway epithelium to smoking.
PloS one.
2013
Academic Article
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Times cited: 5 -
Circulating endothelial microparticles as a measure of early lung destruction in cigarette smokers.
American journal of respiratory and critical care medicine.
2011
Academic Article
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Times cited: 180 -
The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia.
American journal of physiology. Lung cellular and molecular physiology.
2010
Academic Article
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Times cited: 246 -
Dramatic improvement in pulmonary hypertension with rapamycin.
2010
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Times cited: 21 -
Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo.
Cellular and molecular life sciences : CMLS.
2010
Academic Article
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Times cited: 160 -
Threshold of biologic responses of the small airway epithelium to low levels of tobacco smoke.
American journal of respiratory and critical care medicine.
2010
Academic Article
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Times cited: 68 -
Proinflammatory phenotype and increased caveolin-1 in alveolar macrophages with silenced CFTR mRNA.
PloS one.
2010
Academic Article
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Times cited: 40 -
Smoking is associated with shortened airway cilia.
PloS one.
2009
Academic Article
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Times cited: 151 -
Disparate oxidant gene expression of airway epithelium compared to alveolar macrophages in smokers.
Respiratory research.
2009
Academic Article
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Times cited: 19 -
Quality control in microarray assessment of gene expression in human airway epithelium.
BMC genomics.
2009
Academic Article
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Times cited: 65 -
Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease.
Journal of immunology (Baltimore, Md. : 1950).
2009
Academic Article
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Times cited: 297 -
Cigarette smoking induces overexpression of a fat-depleting gene AZGP1 in the human.
Chest.
2009
Academic Article
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Times cited: 31 -
Emphysema mediated by lung overexpression of ADAM10.
Clinical and translational science.
2009
Academic Article
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Times cited: 9 -
Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine.
2008
Academic Article
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Times cited: 149 -
Decreased expression of intelectin 1 in the human airway epithelium of smokers compared to nonsmokers.
Journal of immunology (Baltimore, Md. : 1950).
2008
Academic Article
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Times cited: 35 -
Overexpression of apoptotic cell removal receptor MERTK in alveolar macrophages of cigarette smokers.
American journal of respiratory cell and molecular biology.
2008
Academic Article
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Times cited: 45 -
Variability in small airway epithelial gene expression among normal smokers.
Chest.
2008
Academic Article
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Times cited: 42 -
Responses of the human airway epithelium transcriptome to in vivo injury.
Physiological genomics.
2006
Academic Article
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Times cited: 36 -
Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers.
Cancer research.
2006
Academic Article
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Times cited: 62 -
Modification of gene expression of the small airway epithelium in response to cigarette smoking.
Journal of molecular medicine (Berlin, Germany).
2006
Academic Article
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Times cited: 154 -
Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking.
Journal of molecular medicine (Berlin, Germany).
2006
Academic Article
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Times cited: 78 -
Similarity of gene expression patterns in human alveolar macrophages in response to Pseudomonas aeruginosa and Burkholderia cepacia.
Infection and immunity.
2005
Academic Article
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Times cited: 6 -
Sampling-dependent up-regulation of gene expression in sequential samples of human airway epithelial cells.
Molecular medicine (Cambridge, Mass.).
2003
Academic Article
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Times cited: 9 -
Variability of antioxidant-related gene expression in the airway epithelium of cigarette smokers.
American journal of respiratory cell and molecular biology.
2003
Academic Article
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Times cited: 174 -
Monoallelic up-regulation of the imprinted H19 gene in airway epithelium of phenotypically normal cigarette smokers.
Cancer research.
2003
Academic Article
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Times cited: 51 -
Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions.
Human gene therapy.
2002
Academic Article
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Times cited: 72 -
Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditions.
Human gene therapy.
2002
Academic Article
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Times cited: 123 -
Host responses and persistence of vector genome following intrabronchial administration of an E1(-)E3(-) adenovirus gene transfer vector to normal individuals.
Molecular therapy : the journal of the American Society of Gene Therapy.
2001
Academic Article
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Times cited: 27 -
Rapid assessment of adenovirus serum neutralizing antibody titer based on quantitative, morphometric evaluation of capsid binding and intracellular trafficking: population analysis of adenovirus capsid association with cells is predictive of adenovirus infectivity.
Journal of virology.
2001
Academic Article
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Times cited: 20 -
Cellular immune responses of healthy individuals to intradermal administration of an E1-E3- adenovirus gene transfer vector.
Human gene therapy.
1999
Academic Article
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Times cited: 62 -
Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus.
The Journal of clinical investigation.
1999
Academic Article
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Times cited: 204 -
Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs.
Journal of virology.
1999
Academic Article
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Times cited: 134 -
Phase I study of direct administration of a replication deficient adenovirus vector containing the E. coli cytosine deaminase gene to metastatic colon carcinoma of the liver in association with the oral administration of the pro-drug 5-fluorocytosine.
Human gene therapy.
1997
Academic Article
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Times cited: 124 -
Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype.
Human gene therapy.
1997
Academic Article
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Times cited: 174 -
Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ.
Journal of virology.
1997
Academic Article
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Times cited: 191 -
"Sero-switch" adenovirus-mediated in vivo gene transfer: circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype.
Human gene therapy.
1996
Academic Article
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Times cited: 182 -
Evaluation of repeat administration of a replication deficient, recombinant adenovirus containing the normal cystic fibrosis transmembrane conductance regulator cDNA to the airways of individuals with cystic fibrosis.
Human gene therapy.
1995
Academic Article
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Times cited: 34