selected publications
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Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection.
Nature medicine.
2020
Academic Article
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Times cited: 177 -
The NASA Twins Study: The Effect of One Year in Space on Long-Chain Fatty Acid Desaturases and Elongases.
Lifestyle genomics.
2020
Academic Article
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Times cited: 7 -
Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML.
Cancer discovery.
2019
Academic Article
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Times cited: 28 -
Growth Kinetics, Carbon Isotope Fractionation, and Gene Expression in the Hyperthermophile Methanocaldococcus jannaschii during Hydrogen-Limited Growth and Interspecies Hydrogen Transfer.
Applied and environmental microbiology.
2019
Academic Article
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Times cited: 17 -
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.
Science (New York, N.Y.).
2019
Academic Article
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Times cited: 466 -
Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response.
Nature communications.
2019
Academic Article
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Times cited: 62 -
Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis.
Nature immunology.
2018
Academic Article
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Times cited: 53 -
ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2.
eLife.
2018
Academic Article
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Times cited: 103 -
rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline.
PLoS genetics.
2017
Academic Article
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Times cited: 45 -
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells.
Nature genetics.
2017
Academic Article
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Times cited: 63 -
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.
Cancer discovery.
2017
Academic Article
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Times cited: 84 -
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia.
Cancer discovery.
2017
Academic Article
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Times cited: 82 -
Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells.
Blood.
2017
Academic Article
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Times cited: 16 -
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.
Cancer discovery.
2016
Academic Article
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Times cited: 181 -
The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium inaugural meeting report.
Microbiome.
2016
Conference Paper
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Times cited: 55 -
Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis.
The Journal of experimental medicine.
2015
Academic Article
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Times cited: 112 -
Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome.
Nature methods.
2015
Academic Article
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Times cited: 900 -
Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.
Cancer cell.
2015
Academic Article
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Times cited: 170 -
Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics.
Cell systems.
2015
Academic Article
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Times cited: 84 -
An integrative computational approach for prioritization of genomic variants.
PloS one.
2014
Academic Article
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Times cited: 7 -
Target-independent prediction of drug synergies using only drug lipophilicity.
Journal of chemical information and modeling.
2014
Academic Article
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Times cited: 26