Scherl, Ellen J

Publications

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selected publications

Increased Primary Bile Acids with Ileocolonic Resection Impact Ileal Inflammation and Gut Microbiota in Inflammatory Bowel Disease. Journal of Crohn's & colitis. 2023 Academic Article GET IT
The Impact of Confounders on Symptom-Endoscopic Discordances in Crohn's Disease. Crohn's & colitis 360. 2023 Academic Article GET IT
Long-Term Outcomes of the Excluded Rectum in Crohn's Disease: A Multicenter International Study. Inflammatory bowel diseases. 2023 Review GET IT
Utility of Therapeutic Drug Monitoring for Tumor Necrosis Factor Antagonists and Ustekinumab in Postoperative Crohn's Disease. Inflammatory bowel diseases. 2022 Academic Article GET IT
Serum Ustekinumab Concentrations Are Associated With Improved Outcomes With the Magnetic Resonance Index of Activity for Crohn's Disease. Inflammatory bowel diseases. 2022 Academic Article GET IT
The Real-World Effectiveness and Safety of Ustekinumab in the Treatment of Crohn's Disease: Results From the SUCCESS Consortium. The American journal of gastroenterology. 2022 Academic Article GET IT
Times cited: 6
Prevalence and factors associated with vitamin C deficiency in inflammatory bowel disease. World journal of gastroenterology. 2022 Academic Article GET IT
Times cited: 4
Efficacy and Safety of Maintenance Ustekinumab for Ulcerative Colitis Through 3 Years: UNIFI Long-term Extension. Journal of Crohn's & colitis. 2022 Academic Article GET IT
Times cited: 15
Diagnosis and Management of Cuffitis: A Systematic Review. Diseases of the colon and rectum. 2022 Academic Article GET IT
Times cited: 1
Author Correction: Immune regulation by fungal strain diversity in inflammatory bowel disease. Nature. 2022 Article GET IT
Times cited: 1
Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium. The lancet. Gastroenterology & hepatology. 2022 Review GET IT
Times cited: 3
CORE-IBD: A Multidisciplinary International Consensus Initiative to Develop a Core Outcome Set for Randomized Controlled Trials in Inflammatory Bowel Disease. Gastroenterology. 2022 Academic Article GET IT
Times cited: 7
Ustekinumab Exposure in Pregnant Women From Inflammatory Bowel Disease Clinical Trials: Pregnancy Outcomes Through Up To 5 Years in Crohn's Disease and 2 Years in Ulcerative Colitis. Crohn's & colitis 360. 2022 Academic Article GET IT
Ustekinumab versus adalimumab for induction and maintenance therapy in biologic-naive patients with moderately to severely active Crohn's disease: a multicentre, randomised, double-blind, parallel-group, phase 3b trial. Lancet (London, England). 2022 Academic Article GET IT
Times cited: 37
Mucosal metabolites fuel the growth and virulence of E. coli linked to Crohn's disease. JCI insight. 2022 Academic Article GET IT
Times cited: 6
Immune regulation by fungal strain diversity in inflammatory bowel disease. Nature. 2022 Academic Article GET IT
Times cited: 46
Antitumor Necrosis Factor-like Ligand 1A Therapy Targets Tissue Inflammation and Fibrosis Pathways and Reduces Gut Pathobionts in Ulcerative Colitis. Inflammatory bowel diseases. 2022 Academic Article GET IT
Times cited: 8
A Quality Improvement Initiative Is Associated With Reduced Time to Administer Biologics and Small Molecules and Emergency Room Visits in Inflammatory Bowel Disease. Journal of clinical gastroenterology. 2022 Academic Article GET IT
Times cited: 3
Joint Disease Activity in Inflammatory Bowel Disease-associated Peripheral Spondyloarthritis Stratifies Therapeutic Response. Gastro hep advances. 2022 Academic Article GET IT
Impact of Inflammatory Bowel Disease Therapies on Durability of Humoral Response to SARS-CoV-2 Vaccination. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2021 Letter GET IT
Times cited: 9
Treatment of pouchitis, Crohn's disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium. 2021 GET IT
Times cited: 16
Transferable Immunoglobulin A-Coated Odoribacter splanchnicus in Responders to Fecal Microbiota Transplantation for Ulcerative Colitis Limits Colonic Inflammation. Gastroenterology. 2021 Academic Article GET IT
Times cited: 27
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. Cell stem cell. 2021 Academic Article GET IT
Times cited: 9
Immunogenicity of Tumor Necrosis Factor Antagonists and Effect of Dose Escalation on Anti-Drug Antibodies and Serum Drug Concentrations in Inflammatory Bowel Disease. Inflammatory bowel diseases. 2021 Academic Article GET IT
Times cited: 14
Diagnosis and classification of ileal pouch disorders: consensus guidelines from the International Ileal Pouch Consortium. The lancet. Gastroenterology & hepatology. 2021 Review GET IT
Times cited: 37
Anti-TL1A Antibody PF-06480605 Safety and Efficacy for Ulcerative Colitis: A Phase 2a Single-Arm Study. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2021 Academic Article GET IT
Times cited: 17
No Durable Impact of COVID-19 on Intestinal Disease Activity in Subjects With IBD. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2021 Academic Article GET IT
Times cited: 7
A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults With Crohn's Disease. Gastroenterology. 2021 Academic Article GET IT
Times cited: 71
Ileal Pouch Anal Anastomosis for the Management of Ulcerative Colitis Is Associated With Significant Disability. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2021 Academic Article GET IT
Times cited: 6
Biologics for Inflammatory Bowel Disease and Their Safety in Pregnancy. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2021 Letter GET IT
Times cited: 2
Dual Biologic or Small Molecule Therapy for Treatment of Inflammatory Bowel Disease: A Systematic Review and Meta-analysis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2021 Review GET IT
Times cited: 44
Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease. American journal of human genetics. 2021 Academic Article GET IT
Times cited: 12
Adherent-invasive E. coli metabolism of propanediol in Crohn's disease regulates phagocytes to drive intestinal inflammation. Cell host & microbe. 2021 Academic Article GET IT
Times cited: 36
Utility of magnetic resonance imaging in Crohn's associated sacroiliitis: A cross-sectional study. International journal of rheumatic diseases. 2021 Academic Article GET IT
Times cited: 1
Ustekinumab is effective and safe for ulcerative colitis through 2 years of maintenance therapy. Alimentary pharmacology & therapeutics. 2020 Academic Article GET IT
Times cited: 34
Patient-Preferences Favoring Treatment Discontinuation Are Reduced With Vedolizumab and Ustekinumab Compared With TNF Antagonists in Inflammatory Bowel Disease. Crohn's & colitis 360. 2020 Academic Article GET IT
Short Chain Fatty Acids Modulate the Growth and Virulence of Pathosymbiont Escherichia coli and Host Response. Antibiotics (Basel, Switzerland). 2020 Academic Article GET IT
Times cited: 90
Vitamin C Deficiency: An Under-Recognized Condition in Crohn's Disease. 2020 GET IT
Baseline Disease Activity and Steroid Therapy Stratify Risk of COVID-19 in Patients With Inflammatory Bowel Disease. Gastroenterology. 2020 Academic Article GET IT
Times cited: 84
Defining the phenotype, pathogenesis and treatment of Crohn's disease associated spondyloarthritis. Journal of gastroenterology. 2020 Review GET IT
Times cited: 4
Efficacy and Safety of Upadacitinib in a Randomized Trial of Patients With Crohn's Disease. Gastroenterology. 2020 Academic Article GET IT
Times cited: 124
Withdrawal: Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease: Evidence for involvement of the transcription factor Egr-1. The Journal of biological chemistry. 2020 Academic Article GET IT
Inflammatory bowel disease readmissions are associated with utilization and comorbidity. The American journal of managed care. 2019 Academic Article GET IT
Times cited: 8
Digital Health Apps in the Clinical Care of Inflammatory Bowel Disease: Scoping Review. Journal of medical Internet research. 2019 Review GET IT
Times cited: 43
Takotsubo cardiomyopathy after an upper and lower endoscopy: a case report and review of the literature. Journal of medical case reports. 2019 Review GET IT
Times cited: 2
Risk of Early Colorectal Cancers Needs to Be Considered in Inflammatory Bowel Disease Care. Digestive diseases and sciences. 2019 Academic Article GET IT
Times cited: 8
Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis. Cell host & microbe. 2019 Academic Article GET IT
Times cited: 255
Fragmented Care is Prevalent Among Inflammatory Bowel Disease Readmissions and is Associated With Worse Outcomes. The American journal of gastroenterology. 2019 Academic Article GET IT
Times cited: 26
Disability in inflammatory bowel disease patients is associated with race, ethnicity and socio-economic factors. Alimentary pharmacology & therapeutics. 2019 Academic Article GET IT
Times cited: 14
Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis. Immunity. 2018 Academic Article GET IT
Times cited: 83
Evaluation of Escherichia coli pathotypes associated with irritable bowel syndrome. FEMS microbiology letters. 2018 Academic Article GET IT
Times cited: 9
The Impact of Opioid Epidemic Trends on Hospitalised Inflammatory Bowel Disease Patients. Journal of Crohn's & colitis. 2018 Academic Article GET IT
Times cited: 26
5-Aminosalicylic acid downregulates the growth and virulence of Escherichia coli associated with IBD and colorectal cancer, and upregulates host anti-inflammatory activity. The Journal of antibiotics. 2018 Academic Article GET IT
Times cited: 19
Delays in Initiating Post-operative Prophylactic Biologic Therapy Are Common Among Crohn's Disease Patients. Digestive diseases and sciences. 2018 Academic Article GET IT
Times cited: 8
Testing and Treating Small Intestinal Bacterial Overgrowth Reduces Symptoms in Patients with Inflammatory Bowel Disease. Digestive diseases and sciences. 2018 Academic Article GET IT
Times cited: 14
A Unique Infusion Reaction to Vedolizumab in a Patient With Crohn's Disease. 2018 GET IT
Times cited: 5
Rifaximin decreases virulence of Crohn's disease-associated Escherichia coli and epithelial inflammatory responses. The Journal of antibiotics. 2018 Academic Article GET IT
Times cited: 10
Risk Stratification for Prevention of Recurrence of Postoperative Crohn's Disease. Gastroenterology & hepatology. 2017 Academic Article GET IT
Premedication Use in Preventing Acute Infliximab Infusion Reactions in Patients with Inflammatory Bowel Disease: A Single Center Cohort Study. Inflammatory bowel diseases. 2017 Academic Article GET IT
Times cited: 12
Advances in the Diagnosis and Management of Colonic Dysplasia in Patients With Inflammatory Bowel Disease. Gastroenterology & hepatology. 2017 Academic Article GET IT
Single Delivery of High-Diversity Fecal Microbiota Preparation by Colonoscopy Is Safe and Effective in Increasing Microbial Diversity in Active Ulcerative Colitis. Inflammatory bowel diseases. 2017 Academic Article GET IT
Times cited: 79
Adherence to Postoperative Endoscopic Surveillance in Patients with Crohn's Disease. Inflammatory bowel diseases. 2017 Letter GET IT
Times cited: 1
Reply. Inflammatory bowel diseases. 2017 Letter GET IT
IgA-coated E. coli enriched in Crohn's disease spondyloarthritis promote T_H17-dependent inflammation. Science translational medicine. 2017 Academic Article GET IT
Times cited: 204
The Cost-Effectiveness of Vedolizumab for Inflammatory Bowel Disease: A Review of the Current Literature. Gastroenterology & hepatology. 2016 Academic Article GET IT
Reinduction with Certolizumab Pegol in Patients with Crohn's Disease Experiencing Disease Exacerbation: 7-Year Data from the PRECiSE 4 Study. Inflammatory bowel diseases. 2016 Academic Article GET IT
Times cited: 6
A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF. Gastroenterology. 2016 Academic Article GET IT
Times cited: 42
Crohn's Disease: Evolution, Epigenetics, and the Emerging Role of Microbiome-Targeted Therapies. Current gastroenterology reports. 2016 Review GET IT
Times cited: 13
The Effect of Breathing, Movement, and Meditation on Psychological and Physical Symptoms and Inflammatory Biomarkers in Inflammatory Bowel Disease: A Randomized Controlled Trial. Inflammatory bowel diseases. 2015 Academic Article GET IT
Times cited: 62
Vedolizumab and Infliximab Combination Therapy in the Treatment of Crohn's Disease. The American journal of gastroenterology. 2015 Letter GET IT
Times cited: 38
Id1 expression in endothelial cells of the colon is required for normal response to injury. The American journal of pathology. 2015 Academic Article GET IT
Times cited: 7
Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans. Gastroenterology. 2015 Academic Article GET IT
Times cited: 53
Exercise and Self-Reported Limitations in Patients with Inflammatory Bowel Disease. Digestive diseases and sciences. 2015 Academic Article GET IT
Times cited: 39
Risk of New or Recurrent Cancer in Patients With Inflammatory Bowel Disease and Previous Cancer Exposed to Immunosuppressive and Anti-Tumor Necrosis Factor Agents. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2015 Academic Article GET IT
Times cited: 77
Pneumocystis jiroveci pneumonia with recurrent pneumothorax requiring pleurodesis in inflammatory bowel disease. 2015 GET IT
Times cited: 2
Letter: low muscle mass and disordered eating as causes of osteopenia in inflammatory bowel disease. Alimentary pharmacology & therapeutics. 2015 Letter GET IT
Times cited: 3
Ulcerative Colitis Care Pathway. Gastroenterology. 2015 Review GET IT
Times cited: 74
Cerebral venous thrombosis in inflammatory bowel disease. 2015 GET IT
Times cited: 19
Inflammation-associated adherent-invasive Escherichia coli are enriched in pathways for use of propanediol and iron and M-cell translocation. Inflammatory bowel diseases. 2014 Academic Article GET IT
Times cited: 105
Adenocarcinoma of the ileal pouch mucosa: case report and literature review. International journal of colorectal disease. 2014 Review GET IT
Times cited: 8
ID1 is a functional marker for intestinal stem and progenitor cells required for normal response to injury. Stem cell reports. 2014 Academic Article GET IT
Times cited: 30
CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22. The Journal of experimental medicine. 2014 Academic Article GET IT
Times cited: 274
S1P₁ localizes to the colonic vasculature in ulcerative colitis and maintains blood vessel integrity. Journal of lipid research. 2013 Academic Article GET IT
Times cited: 49
Multidrug resistance is common in Escherichia coli associated with ileal Crohn's disease. Inflammatory bowel diseases. 2013 Academic Article GET IT
Times cited: 57
Rifaximin resistance in Escherichia coli associated with inflammatory bowel disease correlates with prior rifaximin use, mutations in rpoB, and activity of Phe-Arg-β-naphthylamide-inhibitable efflux pumps. Antimicrobial agents and chemotherapy. 2012 Academic Article GET IT
Times cited: 51
Inflammation drives dysbiosis and bacterial invasion in murine models of ileal Crohn's disease. PloS one. 2012 Academic Article GET IT
Times cited: 148
Peripheral neuropathic symptoms in celiac disease and inflammatory bowel disease. Journal of clinical neuromuscular disease. 2012 Academic Article GET IT
Times cited: 30
Anti-nuclear antibody positivity and the use of certolizumab in inflammatory bowel disease patients who have had arthralgias or lupus-like reactions from infliximab or adalimumab. Journal of digestive diseases. 2011 Academic Article GET IT
Times cited: 25
Review of the safety and efficacy of ustekinumab. Therapeutic advances in gastroenterology. 2010 Academic Article GET IT
Times cited: 37
Crohn's disease is associated with restless legs syndrome. Inflammatory bowel diseases. 2010 Academic Article GET IT
Times cited: 72
Safety and efficacy of a new 3.3 g b.i.d. tablet formulation in patients with mild-to-moderately-active ulcerative colitis: a multicenter, randomized, double-blind, placebo-controlled study. The American journal of gastroenterology. 2009 Academic Article GET IT
Times cited: 40
A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease. Gastroenterology. 2008 Academic Article GET IT
Times cited: 639
Prophylaxis against Pneumocystis pneumonia in patients with inflammatory bowel disease: toward a standard of care. Inflammatory bowel diseases. 2008 Review GET IT
Times cited: 31
Predicting Outcomes and Tailoring Therapy in the Diagnosis and Treatment of IBD. Gastroenterology & hepatology. 2007 Academic Article GET IT
Mesalamine-induced Pneumonitis and Serum Sickness-like Reaction. 2007 GET IT
Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in Crohn's disease involving the ileum. The ISME journal. 2007 Academic Article GET IT
Times cited: 486
Mucosal dysplasia in ileal pelvic pouches after restorative proctocolectomy. Diseases of the colon and rectum. 2007 Academic Article GET IT
Times cited: 38
Case report: lymphoma arising in an ileal pouch anal anastomosis after immunomodulatory therapy for inflammatory bowel disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2006 Comment GET IT
Times cited: 35
Levels of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease: evidence for involvement of TNF-alpha. American journal of physiology. Gastrointestinal and liver physiology. 2005 Academic Article GET IT
Times cited: 70
Inflammation's role in rectal cancer following prostate radiotherapy, and emerging evidence for a protective role for balsalazide. Gastroenterology. 2005 Letter GET IT
Times cited: 3
Inflammatory bowel disease in patients with celiac disease. Inflammatory bowel diseases. 2005 Academic Article GET IT
Times cited: 106
The effect on the fetus of medications used to treat pregnant inflammatory bowel-disease patients. The American journal of gastroenterology. 2004 Academic Article GET IT
Times cited: 180
Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1. The Journal of biological chemistry. 2004 Academic Article GET IT
Times cited: 117
Irritable bowel syndrome genophenomics: correlation of serotonin-transporter polymorphisms and alosetron response. The pharmacogenomics journal. 2003 Comment GET IT
Times cited: 7
Optimization and individualization of thiopurine therapy in inflammatory bowel disease: the great variability among drug responses. The pharmacogenomics journal. 2003 Comment GET IT
Irritable-inflammatory bowel disease: recognizing a new overlap syndrome and an enigma wrapped inside a puzzle. Inflammatory bowel diseases. 2002 Comment GET IT
Times cited: 6
Colonoscopy in inflammatory bowel disease. Gastrointestinal endoscopy clinics of North America. 2002 Review GET IT
Times cited: 39
Avoidance of steroids by the early use of infliximab and 6-mercaptopurine in an adolescent with active Crohn's colitis. The American journal of gastroenterology. 2001 Letter GET IT
Times cited: 7
Anti-Saccharomyces cerevisiae antibodies (ASCA), phenotypes of IBD, and intestinal permeability: a study in IBD families. Inflammatory bowel diseases. 2001 Academic Article GET IT
Times cited: 159
Intravenous cyclosporine in refractory pyoderma gangrenosum complicating inflammatory bowel disease. 2001 GET IT
Times cited: 71
Esophageal motility and symptoms after endoscopic injection sclerotherapy. Digestive diseases and sciences. 1985 Academic Article GET IT
Times cited: 38
Pseudodiverticula secondary to injection sclerotherapy. 1983 GET IT
Times cited: 3
Bacteremia after endoscopic injection sclerosis. Gastrointestinal endoscopy. 1983 Academic Article GET IT
Times cited: 103

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Research

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Co-investigator Network

Funding awarded

Molecular and clinical characterization of IBD patients naive or refractory to standard of care over time awarded by Boehringer Ingelheim Pharmaceuticals, Inc. (Germany) Co-Investigator 2023 - 2024

Pregnancy in Inflammatory Bowel Disease And Neonatal Outcomes (PIANO) awarded by National Institute of Mental Health Principal Investigator Subaward 2022 - 2025

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Background

education and training

M.D., New York Medical College 1977
B.A., Barnard College - Columbia University 1974

Contact

full name

Ellen J Scherl

primary email

ejs2005@med.cornell.edu

webpage

Clinical Profile

VIVO Weill Cornell Medical College

Ellen J Scherl Professor of Clinical Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage