selected publications
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Commentary: "Emergency Use Authorization for Remdesivir: A Pediatric Perspective".
The Pediatric infectious disease journal.
2020
Academic Article
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Times cited: 1 -
Key clinical research priorities for the pediatric community during the COVID-19 pandemic.
Pediatric research.
2020
Academic Article
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Times cited: 4 -
Advancing Pediatric Antibacterial Drug Development: A Critical Need to Reinvent our Approach.
Journal of the Pediatric Infectious Diseases Society.
2019
Review
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Times cited: 4 -
Facilitators and barriers to the successful implementation of pediatric antibacterial drug trials: Findings from CTTI's survey of investigators.
Contemporary clinical trials communications.
2018
Academic Article
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Times cited: 1 -
Perceived barriers to pediatrician and family practitioner participation in pediatric clinical trials: Findings from the Clinical Trials Transformation Initiative.
Contemporary clinical trials communications.
2017
Academic Article
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Times cited: 10 -
Improving Conduct and Feasibility of Clinical Trials to Evaluate Antibacterial Drugs to Treat Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia: Recommendations of the Clinical Trials Transformation Initiative Antibacterial Drug Development Project Team.
2016
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Times cited: 15 -
Assessment of musculoskeletal toxicity 5 years after therapy with levofloxacin.
Pediatrics.
2014
Academic Article
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Times cited: 49 -
Children's medicines in Tanzania: a national survey of administration practices and preferences.
PloS one.
2013
Academic Article
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Times cited: 24 -
Improving drug formulations for neonates: making a big difference in our smallest patients.
The Journal of pediatrics.
2012
Academic Article
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Times cited: 7 -
A randomized, evaluator-blind, phase 2 study comparing the safety and efficacy of omadacycline to those of linezolid for treatment of complicated skin and skin structure infections.
Antimicrobial agents and chemotherapy.
2012
Academic Article
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Times cited: 73 -
A randomised, double-blind trial comparing ceftobiprole medocaril with ceftriaxone with or without linezolid for the treatment of patients with community-acquired pneumonia requiring hospitalisation.
International journal of antimicrobial agents.
2012
Academic Article
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Times cited: 99 -
Pharmacometrics-based dose selection of levofloxacin as a treatment for postexposure inhalational anthrax in children.
Antimicrobial agents and chemotherapy.
2009
Academic Article
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Times cited: 39 -
Pharmacodynamic profiling of ceftobiprole for treatment of complicated skin and skin structure infections.
Antimicrobial agents and chemotherapy.
2009
Academic Article
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Times cited: 13 -
Identifying exposure targets for treatment of staphylococcal pneumonia with ceftobiprole.
Antimicrobial agents and chemotherapy.
2009
Academic Article
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Times cited: 57 -
Population pharmacokinetic analysis of ceftobiprole for treatment of complicated skin and skin structure infections.
Antimicrobial agents and chemotherapy.
2008
Academic Article
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Times cited: 10 -
A randomized comparative study of levofloxacin versus amoxicillin/clavulanate for treatment of infants and young children with recurrent or persistent acute otitis media.
The Pediatric infectious disease journal.
2008
Academic Article
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Times cited: 30 -
A randomized, double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2008
Academic Article
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Times cited: 220 -
Characterization and dynamics of middle ear fluid and nasopharyngeal isolates of Streptococcus pneumoniae from 12 children treated with levofloxacin.
Antimicrobial agents and chemotherapy.
2007
Academic Article
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Times cited: 5 -
Results of a double-blind, randomized trial of ceftobiprole treatment of complicated skin and skin structure infections caused by gram-positive bacteria.
Antimicrobial agents and chemotherapy.
2007
Academic Article
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Times cited: 173 -
Comparative safety profile of levofloxacin in 2523 children with a focus on four specific musculoskeletal disorders.
The Pediatric infectious disease journal.
2007
Academic Article
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Times cited: 90 -
Comparative study of levofloxacin in the treatment of children with community-acquired pneumonia.
The Pediatric infectious disease journal.
2007
Academic Article
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Times cited: 61 -
Clinical profile of ceftobiprole, a novel beta-lactam antibiotic.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
2007
Review
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Times cited: 44 -
Anti-MRSA beta-lactams in development, with a focus on ceftobiprole: the first anti-MRSA beta-lactam to demonstrate clinical efficacy.
Expert opinion on investigational drugs.
2007
Review
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Times cited: 67 -
Probability of target attainment for ceftobiprole as derived from a population pharmacokinetic analysis of 150 subjects.
Antimicrobial agents and chemotherapy.
2007
Academic Article
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Times cited: 67 -
An open-label, double tympanocentesis study of levofloxacin therapy in children with, or at high risk for, recurrent or persistent acute otitis media.
The Pediatric infectious disease journal.
2006
Academic Article
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Times cited: 33 -
Achilles tendon rupture and its association with fluoroquinolone antibiotics and other potential risk factors in a managed care population.
Pharmacoepidemiology and drug safety.
2006
Academic Article
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Times cited: 72 -
Levofloxacin pharmacokinetics in children.
Journal of clinical pharmacology.
2005
Academic Article
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Times cited: 64 -
Measuring the effects of supratherapeutic doses of levofloxacin on healthy volunteers using four methods of QT correction and periodic and continuous ECG recordings.
Journal of clinical pharmacology.
2004
Academic Article
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Times cited: 53 -
Susceptibilities to levofloxacin in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis clinical isolates from children: results from 2000-2001 and 2001-2002 TRUST studies in the United States.
Antimicrobial agents and chemotherapy.
2003
Academic Article
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Times cited: 56 -
Effects of three fluoroquinolones on QT interval in healthy adults after single doses.
Clinical pharmacology and therapeutics.
2003
Academic Article
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Times cited: 145 -
Effect of ciprofloxacin on lethal and sublethal challenge with endotoxin and on early cytokine responses in a murine in vivo model.
The Journal of antimicrobial chemotherapy.
2002
Academic Article
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Times cited: 63 -
Tendon or joint disorders in children after treatment with fluoroquinolones or azithromycin.
The Pediatric infectious disease journal.
2002
Academic Article
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Times cited: 85 -
Cytokine modulation with immune gamma-globulin in peripheral blood of normal children and its implications in Kawasaki disease treatment.
Journal of clinical immunology.
2001
Academic Article
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Times cited: 84 -
The effect of three broad-spectrum antimicrobials on mononuclear cell responses to encapsulated bacteria: evidence for down-regulation of cytokine mRNA transcription by trovafloxacin.
The Journal of antimicrobial chemotherapy.
2000
Academic Article
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Times cited: 37 -
Antimicrobial-resistant enterococcal isolates from fluoroquinolone-naive children.
The Pediatric infectious disease journal.
2000
Letter
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Times cited: 4 -
Energy balance, viral burden, insulin-like growth factor-1, interleukin-6 and growth impairment in children infected with human immunodeficiency virus.
AIDS (London, England).
2000
Academic Article
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Times cited: 50 -
Genotypic characterization of human immunodeficiency virus type 1 isolated from vertically infected children with antiretroviral therapy experience.
The Pediatric infectious disease journal.
2000
Academic Article
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Times cited: 9 -
Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia.
The Journal of pediatrics.
1999
Academic Article
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Times cited: 1 -
Effect of changing antiretroviral therapy on human immunodeficiency virus viral load: experience with fifty-four perinatally infected children.
The Pediatric infectious disease journal.
1999
Academic Article
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Times cited: 14 -
Abnormal regulation of interferon-gamma, interleukin-12, and tumor necrosis factor-alpha in human interferon-gamma receptor 1 deficiency.
1998
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Times cited: 137 -
Neuroimaging findings in children perinatally infected with the human immunodeficiency virus.
The Pediatric infectious disease journal.
1998
Academic Article
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Times cited: 27 -
Reversal of proinflammatory responses by ligating the macrophage Fcgamma receptor type I.
The Journal of experimental medicine.
1998
Academic Article
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Times cited: 268 -
An investigation of vancomycin-resistant Enterococcus faecium within the pediatric service of a large urban medical center.
The Pediatric infectious disease journal.
1998
Academic Article
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Times cited: 30 -
Characteristics of human immunodeficiency virus-infected children at the time of death: an experience in the 1990s.
The Pediatric infectious disease journal.
1997
Academic Article
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Times cited: 31 -
Endogenous interleukin-2 serum levels in children infected with human immunodeficiency virus.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
1997
Academic Article
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Times cited: 3 -
Selective suppression of interleukin-12 induction after macrophage receptor ligation.
The Journal of experimental medicine.
1997
Academic Article
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Times cited: 299 -
Effect of amplification of the Cap b locus on complement-mediated bacteriolysis and opsonization of type b Haemophilus influenzae.
Infection and immunity.
1996
Academic Article
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Times cited: 36 -
Neonatal enterococcal bacteremia: an increasingly frequent event with potentially untreatable pathogens.
The Pediatric infectious disease journal.
1996
Academic Article
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Times cited: 57 -
Successful combination vancomycin and rifampin therapy in a newborn with community-acquired Flavobacterium meningosepticum neonatal meningitis.
1995
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Times cited: 13 -
High-molecular-weight proteins of nontypeable Haemophilus influenzae mediate bacterial adhesion to cellular proteoglycans.
Infection and immunity.
1994
Academic Article
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Times cited: 45 -
High-molecular-weight surface-exposed proteins of Haemophilus influenzae mediate binding to macrophages.
The Journal of infectious diseases.
1994
Academic Article
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Times cited: 18 -
Efficacy and safety of dapsone prophylaxis against Pneumocystis carinii pneumonia in human immunodeficiency virus-infected children.
The Pediatric infectious disease journal.
1993
Academic Article
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Times cited: 19 -
Bacteremia due to Pseudomonas aeruginosa in children with AIDS.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
1993
Review
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Times cited: 37 -
Type b capsule inhibits ingestion of Haemophilus influenzae by murine macrophages: studies with isogenic encapsulated and unencapsulated strains.
The Journal of infectious diseases.
1992
Academic Article
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Times cited: 34 -
The role of complement and murine monoclonal antibodies in binding and ingestion of Haemophilus influenzae type b by murine macrophages.
The Journal of infectious diseases.
1992
Academic Article
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Times cited: 3 -
Multiple methicillin-resistant Staphylococcus aureus strains as a cause for a single outbreak of severe disease in hospitalized neonates.
The Pediatric infectious disease journal.
1992
Academic Article
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Times cited: 38 -
In vivo stability of heterogeneous expression classes in clinical isolates of methicillin-resistant staphylococci.
The Journal of infectious diseases.
1991
Academic Article
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Times cited: 36 -
The role of C3 in mediating binding and ingestion of group B streptococcus serotype III by murine macrophages.
Pediatric research.
1991
Academic Article
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Times cited: 18 -
Host defense abnormalities associated with HIV infection.
Pediatric clinics of North America.
1991
Review
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Times cited: 2 -
Persistent bacteremia.
Pediatrics.
1990
Letter
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Times cited: 1 -
Role of complement in mouse macrophage binding of Haemophilus influenzae type b.
The Journal of clinical investigation.
1990
Academic Article
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Times cited: 24 -
Resistance to serum bactericidal activity distinguishes Brazilian purpuric fever (BPF) case strains of Haemophilus influenzae biogroup aegyptius (H. aegyptius) from non-BPF strains. Brazilian Purpuric Fever Study Group.
Journal of clinical microbiology.
1989
Academic Article
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Times cited: 13 -
Anaerobic bacteremia in a neonatal intensive care unit: an eighteen-year experience.
The Pediatric infectious disease journal.
1988
Academic Article
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Times cited: 31 -
Human parvovirus B19 infection in a day care worker.
1988
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Times cited: 1 - Tropical pulmonary eosinophilia in Boston. 1988 GET IT
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Neonatal Staphylococcus epidermidis right-sided endocarditis: description of five catheterized infants.
1988
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Times cited: 69 -
Complement-mediated early clearance of Haemophilus influenzae type b from blood is independent of serum lytic activity.
The Journal of infectious diseases.
1988
Academic Article
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Times cited: 24 -
In vitro activities of selected new and long-acting cephalosporins against Pasteurella multocida.
Antimicrobial agents and chemotherapy.
1986
Academic Article
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Times cited: 25 -
Newborn sepsis following antepartum group B streptococcal maternal infection in rats.
Pediatric research.
1985
Academic Article
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Times cited: 3 -
Staphylococcus epidermidis bacteremia in neonates: further observations and the occurrence of focal infection.
Pediatrics.
1984
Academic Article
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Times cited: 81