Ding, Hong

Publications

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selected publications

Repurposing Metformin for Vascular Disease. Current medicinal chemistry. 2023 Review GET IT
Times cited: 1
Metformin: Is it a drug for all reasons and diseases?. Metabolism: clinical and experimental. 2022 Review GET IT
Times cited: 43
3D Tissue-Engineered Vascular Drug Screening Platforms: Promise and Considerations. Frontiers in cardiovascular medicine. 2022 Review GET IT
Times cited: 45
Metformin Prevents Hyperglycemia-Associated, Oxidative Stress-Induced Vascular Endothelial Dysfunction: Essential Role for the Orphan Nuclear Receptor Human Nuclear Receptor 4A1 (Nur77). Molecular pharmacology. 2021 Academic Article GET IT
Times cited: 11
A Critical Review of the Evidence That Metformin Is a Putative Anti-Aging Drug That Enhances Healthspan and Extends Lifespan. Frontiers in endocrinology. 2021 Review GET IT
Times cited: 35
A Comprehensive Review of Viral Characteristics, Transmission, Pathophysiology, Immune Response, and Management of SARS-CoV-2 and COVID-19 as a Basis for Controlling the Pandemic. Frontiers in immunology. 2021 Review GET IT
Times cited: 83
A Review of the Progress and Challenges of Developing a Vaccine for COVID-19. Frontiers in immunology. 2020 Review GET IT
Times cited: 286
COVID-19: Learning from Lessons To Guide Treatment and Prevention Interventions. mSphere. 2020 Review GET IT
Times cited: 58
Why the endothelium? The endothelium as a target to reduce diabetes-associated vascular disease. Canadian journal of physiology and pharmacology. 2020 Review GET IT
Times cited: 29
Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy. Cancers. 2019 Academic Article GET IT
Times cited: 74
Potent and PPARα-independent anti-proliferative action of the hypolipidemic drug fenofibrate in VEGF-dependent angiosarcomas in vitro. Scientific reports. 2019 Academic Article GET IT
Times cited: 13
Exercise Alleviates Obesity-Induced Metabolic Dysfunction via Enhancing FGF21 Sensitivity in Adipose Tissues. Cell reports. 2019 Academic Article GET IT
Times cited: 90
Minimizing Hyperglycemia-Induced Vascular Endothelial Dysfunction by Inhibiting Endothelial Sodium-Glucose Cotransporter 2 and Attenuating Oxidative Stress: Implications for Treating Individuals With Type 2 Diabetes. Canadian journal of diabetes. 2019 Academic Article GET IT
Times cited: 24
Impact of currently used anti-diabetic drugs on myoendothelial communication. Current opinion in pharmacology. 2018 Review GET IT
Times cited: 6
Hyperglycaemic impairment of PAR2-mediated vasodilation: Prevention by inhibition of aortic endothelial sodium-glucose-co-Transporter-2 and minimizing oxidative stress. Vascular pharmacology. 2018 Academic Article GET IT
Times cited: 70
Hyperglycaemia disrupts conducted vasodilation in the resistance vasculature of db/db mice. Vascular pharmacology. 2018 Academic Article GET IT
Times cited: 12
Metformin represses glucose starvation induced autophagic response in microvascular endothelial cells and promotes cell death. Biochemical pharmacology. 2017 Academic Article GET IT
Times cited: 29
Metformin is not just an antihyperglycaemic drug but also has protective effects on the vascular endothelium. Acta physiologica (Oxford, England). 2016 Review GET IT
Times cited: 76
Molecular Interplay between microRNA-34a and Sirtuin1 in Hyperglycemia-Mediated Impaired Angiogenesis in Endothelial Cells: Effects of Metformin. The Journal of pharmacology and experimental therapeutics. 2015 Academic Article GET IT
Times cited: 74
Metformin improves endothelial function in aortic tissue and microvascular endothelial cells subjected to diabetic hyperglycaemic conditions. Biochemical pharmacology. 2015 Academic Article GET IT
Times cited: 35
Metformin: An Old Drug for the Treatment of Diabetes but a New Drug for the Protection of the Endothelium. Medical principles and practice : international journal of the Kuwait University, Health Science Centre. 2015 Review GET IT
Times cited: 128
MicroRNA Signature and Cardiovascular Dysfunction. Journal of cardiovascular pharmacology. 2015 Review GET IT
Times cited: 29
Fibroblast growth factor 21 prevents atherosclerosis by suppression of hepatic sterol regulatory element-binding protein-2 and induction of adiponectin in mice. Circulation. 2015 Academic Article GET IT
Times cited: 194
Role of SLMAP genetic variants in susceptibility of diabetes and diabetic retinopathy in Qatari population. Journal of translational medicine. 2015 Academic Article GET IT
Times cited: 13
Cardiovascular impact of drugs used in the treatment of diabetes. Therapeutic advances in chronic disease. 2014 Review GET IT
Times cited: 44
FGF21 maintains glucose homeostasis by mediating the cross talk between liver and brain during prolonged fasting. Diabetes. 2014 Academic Article GET IT
Times cited: 186
Luteolin inhibits smooth muscle cell migration and proliferation by attenuating the production of Nox4, p-Akt and VEGF in endothelial cells. Current pharmaceutical biotechnology. 2014 Academic Article GET IT
Times cited: 16
Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1. British journal of pharmacology. 2014 Academic Article GET IT
Times cited: 166
Luteolin inhibits angiotensin II-induced human umbilical vein endothelial cell proliferation and migration through downregulation of Src and Akt phosphorylation. Circulation journal : official journal of the Japanese Circulation Society. 2012 Academic Article GET IT
Times cited: 26
The endothelium: influencing vascular smooth muscle in many ways. Canadian journal of physiology and pharmacology. 2012 Review GET IT
Times cited: 178
The contribution of d-tubocurarine-sensitive and apamin-sensitive K-channels to EDHF-mediated relaxation of mesenteric arteries from eNOS-/- mice. Journal of cardiovascular pharmacology. 2012 Academic Article GET IT
Times cited: 1
Endothelial dysfunction in diabetes mellitus: possible involvement of endoplasmic reticulum stress?. Experimental diabetes research. 2012 Review GET IT
Times cited: 94
Perivascular adipose tissue-derived relaxing factors: release by peptide agonists via proteinase-activated receptor-2 (PAR2) and non-PAR2 mechanisms. British journal of pharmacology. 2011 Academic Article GET IT
Times cited: 17
Increased expression of the tail-anchored membrane protein SLMAP in adipose tissue from type 2 Tally Ho diabetic mice. Experimental diabetes research. 2011 Academic Article GET IT
Times cited: 9
The endothelium in compliance and resistance vessels. Frontiers in bioscience (Scholar edition). 2011 Review GET IT
Times cited: 23
Endothelial dysfunction in diabetes: multiple targets for treatment. Pflugers Archiv : European journal of physiology. 2010 Review GET IT
Times cited: 86
High glucose increases expression of cyclooxygenase-2, increases oxidative stress and decreases the generation of nitric oxide in mouse microvessel endothelial cells. Journal of cellular physiology. 2010 Academic Article GET IT
Times cited: 48
A review of endothelial dysfunction in diabetes: a focus on the contribution of a dysfunctional eNOS. Journal of the American Society of Hypertension : JASH. 2010 Review GET IT
Times cited: 79
Glucose enhances expression of TRPC1 and calcium entry in endothelial cells. American journal of physiology. Heart and circulatory physiology. 2009 Academic Article GET IT
Times cited: 41
Endothelium-dependent vasodilation in myogenically active mouse skeletal muscle arterioles: role of EDH and K(+) channels. Microcirculation (New York, N.Y. : 1994). 2009 Academic Article GET IT
Times cited: 18
Effects of a Western diet versus high glucose on endothelium-dependent relaxation in murine micro- and macro-vasculature. European journal of pharmacology. 2008 Academic Article GET IT
Times cited: 27
Oxidative stress and increased eNOS and NADPH oxidase expression in mouse microvessel endothelial cells. Journal of cellular physiology. 2007 Academic Article GET IT
Times cited: 85
Increased oxidative stress in the streptozotocin-induced diabetic apoE-deficient mouse: changes in expression of NADPH oxidase subunits and eNOS. European journal of pharmacology. 2007 Academic Article GET IT
Times cited: 67
Calcium-activated potassium channel and connexin expression in small mesenteric arteries from eNOS-deficient (eNOS-/-) and eNOS-expressing (eNOS+/+) mice. European journal of pharmacology. 2007 Academic Article GET IT
Times cited: 16
Nitrosothiol stores in vascular tissue: modulation by ultraviolet light, acetylcholine and ionomycin. European journal of pharmacology. 2007 Academic Article GET IT
Times cited: 26
Vascular dysfunction in type 2 diabetic TallyHo mice: role for an increase in the contribution of PGH2/TxA2 receptor activation and cytochrome p450 products. Canadian journal of physiology and pharmacology. 2007 Academic Article GET IT
Times cited: 19
Pharmacological characteristics of endothelium-derived hyperpolarizing factor-mediated relaxation of small mesenteric arteries from db/db mice. European journal of pharmacology. 2006 Academic Article GET IT
Times cited: 45
Widespread vascular production of C-reactive protein (CRP) and a relationship between serum CRP, plaque CRP and intimal hypertrophy. Atherosclerosis. 2006 Academic Article GET IT
Times cited: 33
Endothelial dysfunction in the streptozotocin-induced diabetic apoE-deficient mouse. British journal of pharmacology. 2005 Academic Article GET IT
Times cited: 87
Endothelial dysfunction in Type 2 diabetes correlates with deregulated expression of the tail-anchored membrane protein SLMAP. American journal of physiology. Heart and circulatory physiology. 2005 Academic Article GET IT
Times cited: 19
Endothelial cell dysfunction and the vascular complications associated with type 2 diabetes: assessing the health of the endothelium. Vascular health and risk management. 2005 Review GET IT
Times cited: 94
Twenty-five years since the discovery of endothelium-derived relaxing factor (EDRF): does a dysfunctional endothelium contribute to the development of type 2 diabetes?. Canadian journal of physiology and pharmacology. 2005 Review GET IT
Times cited: 21
The endothelium in health and disease: A discussion of the contribution of non-nitric oxide endothelium-derived vasoactive mediators to vascular homeostasis in normal vessels and in type II diabetes. Molecular and cellular biochemistry. 2004 Academic Article GET IT
Times cited: 32
The endothelium in health and disease: a discussion of the contribution of non-nitric oxide endothelium-derived vasoactive mediators to vascular homeostasis in normal vessels and in type II diabetes. Molecular and cellular biochemistry. 2004 Review GET IT
Times cited: 32
The endothelium in health and disease--a target for therapeutic intervention. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi. 2003 Review GET IT
Times cited: 94
Endothelium-derived hyperpolarizing factor: is there a novel chemical mediator?. Clinical and experimental pharmacology & physiology. 2002 Review GET IT
Times cited: 39
Endothelium-derived relaxing factors: a focus on endothelium-derived hyperpolarizing factor(s). Canadian journal of physiology and pharmacology. 2001 Review GET IT
Times cited: 160
Potassium- and acetylcholine-induced vasorelaxation in mice lacking endothelial nitric oxide synthase. British journal of pharmacology. 2000 Academic Article GET IT
Times cited: 66
Novel endothelium-derived relaxing factors. Identification of factors and cellular targets. Journal of pharmacological and toxicological methods. 2000 Review GET IT
Times cited: 23
Acetylcholine-induced relaxation of peripheral arteries isolated from mice lacking endothelial nitric oxide synthase. British journal of pharmacology. 1999 Academic Article GET IT
Times cited: 115

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Background

education and training

Ph.D., University of Calgary (Canada) 2001
B.M., Zhejiang Medical University (China) 1989

Contact

full name

Hong Ding

primary email

hod2005@qatar-med.cornell.edu

VIVO Weill Cornell Medical College

Hong Ding Associate Professor of Research in Pharmacology

Publications

selected publications

Background

education and training

Contact

full name

primary email