Rogatsky, Inez

Publications

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selected publications

Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression. Nature communications. 2020 Academic Article GET IT
Times cited: 15
Dual Cross-Linking Chromatin Immunoprecipitation Protocol for Next-Generation Sequencing (ChIPseq) in Macrophages. Methods in molecular biology (Clifton, N.J.). 2019 Academic Article GET IT
Times cited: 1
Gene-specific mechanisms direct glucocorticoid-receptor-driven repression of inflammatory response genes in macrophages. eLife. 2018 Academic Article GET IT
Times cited: 40
Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages. Nature communications. 2017 Academic Article GET IT
Times cited: 21
The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis. Nature communications. 2016 Academic Article GET IT
Times cited: 26
The transcriptional repressor Hes1 attenuates inflammation by regulating transcription elongation. Nature immunology. 2016 Academic Article GET IT
Times cited: 55
There goes the neighborhood: Assembly of transcriptional complexes during the regulation of metabolism and inflammation by the glucocorticoid receptor. Steroids. 2016 Review GET IT
Times cited: 23
Glucocorticoid Signaling: An Update from a Genomic Perspective. Annual review of physiology. 2015 Review GET IT
Times cited: 81
Minireview: nuclear receptor coregulators of the p160 family: insights into inflammation and metabolism. Molecular endocrinology (Baltimore, Md.). 2015 Review GET IT
Times cited: 40
Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages. BMC genomics. 2014 Academic Article GET IT
Times cited: 63
Preparing the first responders: building the inflammatory transcriptome from the ground up. Molecular cell. 2014 Review GET IT
Times cited: 33
Epigenetics and the IRFs: a complex interplay in the control of immunity and autoimmunity. Autoimmunity. 2013 Review GET IT
Times cited: 17
Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle. Proceedings of the National Academy of Sciences of the United States of America. 2013 Academic Article GET IT
Times cited: 48
Nuclear receptors in inflammation control: repression by GR and beyond. Molecular and cellular endocrinology. 2013 Review GET IT
Times cited: 47
Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids. Proceedings of the National Academy of Sciences of the United States of America. 2012 Academic Article GET IT
Times cited: 65
Glucocorticoid-dependent phosphorylation of the transcriptional coregulator GRIP1. Molecular and cellular biology. 2011 Academic Article GET IT
Times cited: 22
Minireview: Glucocorticoids in autoimmunity: unexpected targets and mechanisms. Molecular endocrinology (Baltimore, Md.). 2011 Review GET IT
Times cited: 97
The type I interferon signaling pathway is a target for glucocorticoid inhibition. Molecular and cellular biology. 2010 Academic Article GET IT
Times cited: 101
RNA polymerase II stalling mediates cytokine gene expression. Cell cycle (Georgetown, Tex.). 2010 Editorial Article GET IT
Times cited: 6
Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling. Proceedings of the National Academy of Sciences of the United States of America. 2009 Academic Article GET IT
Times cited: 117
Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells. American journal of respiratory cell and molecular biology. 2009 Academic Article GET IT
Times cited: 60
GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression. Proceedings of the National Academy of Sciences of the United States of America. 2008 Academic Article GET IT
Times cited: 25
Glucocorticoid receptor phosphorylation differentially affects target gene expression. Molecular endocrinology (Baltimore, Md.). 2008 Academic Article GET IT
Times cited: 209
Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages. Molecular and cellular biology. 2008 Academic Article GET IT
Times cited: 61
Glucocorticoids and the innate immune system: crosstalk with the toll-like receptor signaling network. Molecular and cellular endocrinology. 2007 Review GET IT
Times cited: 94
Glucocorticoid modulation of cytokine signaling. Tissue antigens. 2006 Review GET IT
Times cited: 116
The glucocorticoid receptor represses cyclin D1 by targeting the Tcf-beta-catenin complex. The Journal of biological chemistry. 2006 Academic Article GET IT
Times cited: 54
The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression. The EMBO journal. 2005 Academic Article GET IT
Times cited: 129
MED14 and MED1 differentially regulate target-specific gene activation by the glucocorticoid receptor. Molecular endocrinology (Baltimore, Md.). 2005 Academic Article GET IT
Times cited: 104
Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta. Molecular biology of the cell. 2003 Academic Article GET IT
Times cited: 197
Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor. Proceedings of the National Academy of Sciences of the United States of America. 2003 Academic Article GET IT
Times cited: 205
Drug discovery for inflammatory diseases. Expert opinion on biological therapy. 2003 Review GET IT
Times cited: 6
Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts. Proceedings of the National Academy of Sciences of the United States of America. 2002 Academic Article GET IT
Times cited: 182
Identification and characterization of ART-27, a novel coactivator for the androgen receptor N terminus. Molecular biology of the cell. 2002 Academic Article GET IT
Times cited: 71
Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones. The EMBO journal. 2001 Academic Article GET IT
Times cited: 154
Selective activation of the glucocorticoid receptor by steroid antagonists in human breast cancer and osteosarcoma cells. The Journal of biological chemistry. 2000 Academic Article GET IT
Times cited: 55
Potentiation of human estrogen receptor alpha transcriptional activation through phosphorylation of serines 104 and 106 by the cyclin A-CDK2 complex. The Journal of biological chemistry. 1999 Academic Article GET IT
Times cited: 153
Distinct glucocorticoid receptor transcriptional regulatory surfaces mediate the cytotoxic and cytostatic effects of glucocorticoids. Molecular and cellular biology. 1999 Academic Article GET IT
Times cited: 90
Phosphorylation and inhibition of rat glucocorticoid receptor transcriptional activation by glycogen synthase kinase-3 (GSK-3). Species-specific differences between human and rat glucocorticoid receptor signaling as revealed through GSK-3 phosphorylation. The Journal of biological chemistry. 1998 Academic Article GET IT
Times cited: 112
Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase. Proceedings of the National Academy of Sciences of the United States of America. 1998 Academic Article GET IT
Times cited: 252
Regulation of estrogen receptor transcriptional enhancement by the cyclin A/Cdk2 complex. Proceedings of the National Academy of Sciences of the United States of America. 1997 Academic Article GET IT
Times cited: 79
Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor. Molecular and cellular biology. 1997 Academic Article GET IT
Times cited: 229
Glucocorticoid receptor-mediated cell cycle arrest is achieved through distinct cell-specific transcriptional regulatory mechanisms. Molecular and cellular biology. 1997 Academic Article GET IT
Times cited: 226

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Background

education and training

Ph.D., New York University, Sackler Institute 1997
M.Sc., Weizmann Institute of Science (Israel) 1993
B.A., Moscow State University (Russia) 1990

Contact

full name

Inez Rogatsky

primary email

inr2005@med.cornell.edu

VIVO Weill Cornell Medical College

Inez Rogatsky Professor of Microbiology and Immunology

Publications

selected publications

Background

education and training

Contact

full name

primary email