selected publications
-
Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML.
Cancer discovery.
2019
Academic Article
GET IT
Times cited: 28 -
Loss of plasmacytoid dendritic cell differentiation is highly predictive for post-induction measurable residual disease and inferior outcomes in acute myeloid leukemia.
Haematologica.
2018
Academic Article
GET IT
Times cited: 10 -
Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis.
Blood.
2018
Academic Article
GET IT
Times cited: 29 -
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells.
Nature genetics.
2017
Academic Article
GET IT
Times cited: 63 -
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.
Cancer discovery.
2017
Academic Article
GET IT
Times cited: 84 -
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia.
Cancer discovery.
2017
Academic Article
GET IT
Times cited: 82 -
LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation.
Cell.
2016
Editorial Article
GET IT
Times cited: 4 -
Dnmt3a regulates myeloproliferation and liver-specific expansion of hematopoietic stem and progenitor cells.
Leukemia.
2015
Academic Article
GET IT
Times cited: 53 -
Late-replicating heterochromatin is characterized by decreased cytosine methylation in the human genome.
Genome research.
2011
Academic Article
GET IT
Times cited: 30 -
LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation.
Cell.
2010
Academic Article
GET IT
Times cited: 239 -
CG dinucleotide periodicities recognized by the Dnmt3a-Dnmt3L complex are distinctive at retroelements and imprinted domains.
Mammalian genome : official journal of the International Mammalian Genome Society.
2009
Academic Article
GET IT
Times cited: 29 -
High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers.
Nucleic acids research.
2009
Academic Article
GET IT
Times cited: 131 -
Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features.
Blood.
2009
Academic Article
GET IT
Times cited: 78 -
CG dinucleotide clustering is a species-specific property of the genome.
Nucleic acids research.
2007
Academic Article
GET IT
Times cited: 70 -
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences.
Nature.
2007
Academic Article
GET IT
Times cited: 560 -
Comparative isoschizomer profiling of cytosine methylation: the HELP assay.
Genome research.
2006
Academic Article
GET IT
Times cited: 341