Garcia-Aguilar, Julio

Publications

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selected publications

A rectal cancer organoid platform to study individual responses to chemoradiation. Nature medicine. 2019 Academic Article GET IT
Times cited: 239
Assessment of a Watch-and-Wait Strategy for Rectal Cancer in Patients With a Complete Response After Neoadjuvant Therapy. JAMA oncology. 2019 Academic Article GET IT
Times cited: 270
Variation in the Thoroughness of Pathologic Assessment and Response Rates of Locally Advanced Rectal Cancers After Chemoradiation. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2019 Academic Article GET IT
Times cited: 3
Lymph node yield in right colectomy for cancer: a comparison of open, laparoscopic and robotic approaches. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 2017 Academic Article GET IT
Times cited: 34
Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing. JAMA. 2017 Academic Article GET IT
Times cited: 289
Anorectal Function and Quality of Life in Patients With Early Stage Rectal Cancer Treated With Chemoradiation and Local Excision. Diseases of the colon and rectum. 2017 Academic Article GET IT
Times cited: 16
Evolving application of minimally invasive cancer operations at a tertiary cancer center. Journal of surgical oncology. 2017 Academic Article GET IT
Times cited: 6
Readmission After Ileostomy Creation: Retrospective Review of a Common and Significant Event. Annals of surgery. 2017 Academic Article GET IT
Times cited: 79
Single Nucleotide Polymorphism TGFβ1 R25P Correlates with Acute Toxicity during Neoadjuvant Chemoradiotherapy in Rectal Cancer Patients. International journal of radiation oncology, biology, physics. 2016 Academic Article GET IT
Times cited: 8
Developing a robotic colorectal cancer surgery program: understanding institutional and individual learning curves. Surgical endoscopy. 2016 Academic Article GET IT
Times cited: 53
Distance to the anal verge is associated with pathologic complete response to neoadjuvant therapy in locally advanced rectal cancer. Journal of surgical oncology. 2016 Academic Article GET IT
Times cited: 26
Incisional hernias after laparoscopic and robotic right colectomy. Hernia : the journal of hernias and abdominal wall surgery. 2016 Academic Article GET IT
Times cited: 26
Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal. Nature communications. 2016 Academic Article GET IT
Times cited: 63
Patterns and prognostic relevance of PD-1 and PD-L1 expression in colorectal carcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2016 Academic Article GET IT
Times cited: 121
Reply to Cristóbal and Co-authors' comment, deregulation of miR-92a in locally advanced rectal cancer. Genes, chromosomes & cancer. 2016 Letter GET IT
Integrated genomic profiling identifies microRNA-92a regulation of IQGAP2 in locally advanced rectal cancer. Genes, chromosomes & cancer. 2016 Academic Article GET IT
Times cited: 9
KRAS and Combined KRAS/TP53 Mutations in Locally Advanced Rectal Cancer are Independently Associated with Decreased Response to Neoadjuvant Therapy. Annals of surgical oncology. 2016 Academic Article GET IT
Times cited: 63
Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Academic Article GET IT
Times cited: 175
Multiparametric MRI in the assessment of response of rectal cancer to neoadjuvant chemoradiotherapy: A comparison of morphological, volumetric and functional MRI parameters. European radiology. 2016 Academic Article GET IT
Times cited: 53
Multimodal Rectal Cancer Treatment: In Some Cases, Less May Be More. American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting. 2016 Review GET IT
Times cited: 10
Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total mesorectal excision or nonoperative management. BMC cancer. 2015 Academic Article GET IT
Times cited: 212
Organ preservation for clinical T2N0 distal rectal cancer using neoadjuvant chemoradiotherapy and local excision (ACOSOG Z6041): results of an open-label, single-arm, multi-institutional, phase 2 trial. The Lancet. Oncology. 2015 Academic Article GET IT
Times cited: 282
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial. The Lancet. Oncology. 2015 Academic Article GET IT
Times cited: 419
Advances and challenges in treatment of locally advanced rectal cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2015 Review GET IT
Times cited: 126
Extended Intervals after Neoadjuvant Therapy in Locally Advanced Rectal Cancer: The Key to Improved Tumor Response and Potential Organ Preservation. Journal of the American College of Surgeons. 2015 Academic Article GET IT
Times cited: 130
Does endoscopic ultrasound improve detection of locally recurrent anal squamous-cell cancer?. Diseases of the colon and rectum. 2015 Academic Article GET IT
Times cited: 7
Comparison of tumor regression grade systems for locally advanced rectal cancer after multimodality treatment. Journal of the National Cancer Institute. 2014 Academic Article GET IT
Times cited: 165
Management and outcome of perianal Paget's disease: a 6-decade institutional experience. Diseases of the colon and rectum. 2014 Academic Article GET IT
Times cited: 36
Multiparametric MRI of rectal cancer in the assessment of response to therapy: a systematic review. Diseases of the colon and rectum. 2014 Review GET IT
Times cited: 71
Neoadjuvant chemotherapy first, followed by chemoradiation and then surgery, in the management of locally advanced rectal cancer. Journal of the National Comprehensive Cancer Network : JNCCN. 2014 Academic Article GET IT
Times cited: 149
Neoadjuvant radiation therapy prior to total mesorectal excision for rectal cancer is not associated with postoperative complications using current techniques. Annals of surgical oncology. 2014 Academic Article GET IT
Times cited: 12
Optimizing rectal cancer management: analysis of current evidence. Diseases of the colon and rectum. 2014 Academic Article GET IT
Times cited: 26
Imaging in rectal cancer: magnetic resonance imaging versus endorectal ultrasonography. Surgical oncology clinics of North America. 2014 Review GET IT
Times cited: 27
Prognostic aspects of DCE-MRI in recurrent rectal cancer. European radiology. 2013 Academic Article GET IT
Times cited: 17
TP53 and let-7a micro-RNA regulate K-Ras activity in HCT116 colorectal cancer cells. PloS one. 2013 Academic Article GET IT
Times cited: 22
Mutations in specific codons of the KRAS oncogene are associated with variable resistance to neoadjuvant chemoradiation therapy in patients with rectal adenocarcinoma. Annals of surgical oncology. 2013 Academic Article GET IT
Times cited: 80
Distribution of residual cancer cells in the bowel wall after neoadjuvant chemoradiation in patients with rectal cancer. Diseases of the colon and rectum. 2013 Academic Article GET IT
Times cited: 76
Locoregional lymphadenectomy in the surgical management of anorectal melanoma. Annals of surgical oncology. 2013 Academic Article GET IT
Times cited: 31
What is the significance of the circumferential margin in locally advanced rectal cancer after neoadjuvant chemoradiotherapy?. Annals of surgical oncology. 2013 Academic Article GET IT
Times cited: 62
Race and correlations between lymph node number and survival for patients with gastric cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2013 Academic Article GET IT
Times cited: 11
Transanal endoscopic microsurgery following neoadjuvant chemoradiation therapy in rectal cancer: a word of caution about patient selection?. Diseases of the colon and rectum. 2013 Editorial Article GET IT
Times cited: 17
Gene polymorphisms predict toxicity to neoadjuvant therapy in patients with rectal cancer. Cancer. 2012 Academic Article GET IT
Times cited: 16
An appraisal of radiofrequency ablation and surgical resection for hepatocellular carcinoma: results from the surveillance, epidemiology, and end results registry. The American surgeon. 2012 Academic Article GET IT
Times cited: 6
The evolution of surgical technique for total gastrectomy over a 12-year period: a single institution's experience. The American surgeon. 2012 Academic Article GET IT
Times cited: 4
Elderly patients with colon cancer have unique tumor characteristics and poor survival. Cancer. 2012 Academic Article GET IT
Times cited: 44
Prognostic and predictive roles of KRAS mutation in colorectal cancer. International journal of molecular sciences. 2012 Review GET IT
Times cited: 147
Transperineal management for postoperative and radiation rectourethral fistulas. The Journal of urology. 2012 Academic Article GET IT
Times cited: 36
The association of hospital volume with rectal cancer surgery outcomes. International journal of colorectal disease. 2012 Academic Article GET IT
Times cited: 43
Evaluation of lymphadenectomy in patients receiving neoadjuvant radiotherapy for rectal adenocarcinoma. Annals of surgical oncology. 2012 Academic Article GET IT
Times cited: 13
Chromosomal copy number alterations are associated with persistent lymph node metastasis after chemoradiation in locally advanced rectal cancer. Diseases of the colon and rectum. 2012 Academic Article GET IT
Times cited: 18
Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression. Nature communications. 2012 Academic Article GET IT
Times cited: 65
Robot-assisted total mesorectal excision: is there a learning curve?. Surgical endoscopy. 2012 Academic Article GET IT
Times cited: 64
Socioeconomic factors impact colon cancer outcomes in diverse patient populations. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2012 Academic Article GET IT
Times cited: 40
Racial and ethnic disparities in outcomes with radiation therapy for rectal adenocarcinoma. International journal of colorectal disease. 2011 Academic Article GET IT
Times cited: 8
Surgical complications and pathologic complete response after neoadjuvant chemoradiation in locally advanced rectal cancer. The American surgeon. 2011 Academic Article GET IT
Times cited: 18
Identification of a biomarker profile associated with resistance to neoadjuvant chemoradiation therapy in rectal cancer. Annals of surgery. 2011 Academic Article GET IT
Times cited: 128
A phase II trial of neoadjuvant chemoradiation and local excision for T2N0 rectal cancer: preliminary results of the ACOSOG Z6041 trial. Annals of surgical oncology. 2011 Academic Article GET IT
Times cited: 235
Gene expression variations in microsatellite stable and unstable colon cancer cells. The Journal of surgical research. 2011 Academic Article GET IT
Times cited: 17
Optimal timing of surgery after chemoradiation for advanced rectal cancer: preliminary results of a multicenter, nonrandomized phase II prospective trial. Annals of surgery. 2011 Academic Article GET IT
Times cited: 241
Venous thromboembolic disease. 2011 GET IT
Times cited: 69
Adjuvant chemotherapy improves survival in patients with American Joint Committee on Cancer stage II colon cancer. Cancer. 2011 Academic Article GET IT
Times cited: 22
Chromosomal copy number alterations are associated with tumor response to chemoradiation in locally advanced rectal cancer. Genes, chromosomes & cancer. 2011 Academic Article GET IT
Times cited: 27
An interaction of race and ethnicity with socioeconomic status in rectal cancer outcomes. Annals of surgery. 2011 Academic Article GET IT
Times cited: 54
Selection criteria for complete cytoreduction after cytoreductive surgery for peritoneal surface malignancy: lessons learned from our first series of patients. The American surgeon. 2011 Academic Article GET IT
Times cited: 1
Molecular diagnosis of response to neoadjuvant chemoradiation therapy in patients with locally advanced rectal cancer. Journal of the American College of Surgeons. 2011 Academic Article GET IT
Times cited: 28
Optimal management of small rectal cancers: TAE, TEM, or TME?. Surgical oncology clinics of North America. 2010 Review GET IT
Times cited: 11
Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data. The Lancet. Oncology. 2010 Academic Article GET IT
Times cited: 1341
Robotic colorectal surgery: for whom and for what?. Diseases of the colon and rectum. 2010 Editorial Article GET IT
Times cited: 43
Oncologic outcomes of robotic-assisted total mesorectal excision for the treatment of rectal cancer. Annals of surgery. 2010 Academic Article GET IT
Times cited: 132
Validation of the risk index category as a predictor of surgical site infection in elective colorectal surgery. Diseases of the colon and rectum. 2010 Academic Article GET IT
Times cited: 39
Totally laparoscopic right colectomy with transvaginal specimen extraction: the authors' initial institutional experience. Surgical endoscopy. 2010 Academic Article GET IT
Times cited: 56
Multicentric study on robotic tumor-specific mesorectal excision for the treatment of rectal cancer. Annals of surgical oncology. 2010 Academic Article GET IT
Times cited: 209
An increase in compliance with the Surgical Care Improvement Project measures does not prevent surgical site infection in colorectal surgery. Diseases of the colon and rectum. 2010 Academic Article GET IT
Times cited: 72
Treatment of transsphincteric anal fistulas: are fistula plugs an acceptable alternative?. Diseases of the colon and rectum. 2009 Academic Article GET IT
Times cited: 54
Canadian Association of General Surgeons, the American College of Surgeons, the Canadian Society of Colorectal Surgeons, and the American Society of Colon and Rectal Surgeons: evidence-based reviews in surgery--colorectal surgery. Diseases of the colon and rectum. 2009 Academic Article GET IT
Times cited: 3
Local excision for rectal carcinoma. Clinical colorectal cancer. 2008 Review GET IT
Times cited: 25
The future of surgical management of colorectal cancer. Diseases of the colon and rectum. 2008 Academic Article GET IT
Times cited: 2
Refractory lower gastrointestinal bleeding from portal hypertensive colopathy. 2008 GET IT
Times cited: 5
Implementation of quality measures to reduce surgical site infection in colorectal patients. Diseases of the colon and rectum. 2008 Academic Article GET IT
Times cited: 49
Dartos muscle interposition flap for the treatment of rectourethral fistulas. Diseases of the colon and rectum. 2007 Academic Article GET IT
Times cited: 27
Organ preservation for rectal cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2007 Review GET IT
Times cited: 68
Patterns of metastasis in human solid cancers. Cancer treatment and research. 2007 Review GET IT
Times cited: 7
Clinical patterns of metastasis. Cancer metastasis reviews. 2006 Review GET IT
Times cited: 100
Aetiology and surgical management of toxic megacolon. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 2006 Academic Article GET IT
Times cited: 42
Surgical treatment of rectal cancer: local resection. Surgical oncology clinics of North America. 2006 Review GET IT
Times cited: 12
The effect of circumferential tumor location in clinical outcomes of rectal cancer patients treated with total mesorectal excision. Diseases of the colon and rectum. 2005 Academic Article GET IT
Times cited: 58
Mechanisms of microsatellite instability in colorectal cancer patients in different age groups. Diseases of the colon and rectum. 2005 Academic Article GET IT
Times cited: 27
[Liver metastases from colorectal cancer. Is the practice of surgery based on the best clinical evidence possible?]. Cirugia espanola. 2005 Review GET IT
Times cited: 2
Endorectal ultrasound in the management of patients with malignant rectal polyps. Diseases of the colon and rectum. 2005 Academic Article GET IT
Times cited: 14
The mechanism of microsatellite instability is different in synchronous and metachronous colorectal cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2005 Academic Article GET IT
Times cited: 25
Interobserver variability in the pathological assessment of malignant colorectal polyps. The British journal of surgery. 2004 Academic Article GET IT
Times cited: 45
Endorectal ultrasound in the follow-up of rectal cancer patients treated by local excision or radical surgery. Diseases of the colon and rectum. 2004 Academic Article GET IT
Times cited: 50
Total mesorectal excision for rectal cancer: the truth lies underneath. World journal of surgery. 2004 Editorial Article GET IT
Times cited: 16
Evidence of a preferred molecular pathway in patients with synchronous colorectal cancer. Cancer. 2003 Academic Article GET IT
Times cited: 34
Quality of life after subtotal colectomy for slow-transit constipation: both quality and quantity count. Diseases of the colon and rectum. 2003 Academic Article GET IT
Times cited: 95
The alpha2 and alpha3 integrins are required for morphologic differentiation of an intestinal epithelial cell line. Surgery. 2003 Academic Article GET IT
Times cited: 21
A pathologic complete response to preoperative chemoradiation is associated with lower local recurrence and improved survival in rectal cancer patients treated by mesorectal excision. Diseases of the colon and rectum. 2003 Academic Article GET IT
Times cited: 334
Salvage radical surgery after failed local excision for early rectal cancer. Diseases of the colon and rectum. 2002 Academic Article GET IT
Times cited: 141
Accuracy of endorectal ultrasonography in preoperative staging of rectal tumors. Diseases of the colon and rectum. 2002 Academic Article GET IT
Times cited: 320
Treatment of locally recurrent rectal cancer. Diseases of the colon and rectum. 2001 Academic Article GET IT
Times cited: 112
Pelvic wall involvement denotes a poor prognosis in T4 rectal cancer. Diseases of the colon and rectum. 2001 Academic Article GET IT
Times cited: 22
Colorectal cancer experimental models. Revista espanola de enfermedades digestivas. 2001 Academic Article GET IT
Role of local excision in the treatment of rectal cancer. Seminars in surgical oncology. 2000 Review GET IT
Times cited: 64
Commentary on 'Current protocols and outcomes of local therapy for rectal Cancer' by bleday and steele. Surgical oncology clinics of North America. 2000 Academic Article GET IT
Patient satisfaction after surgical treatment for fistula-in-ano. Diseases of the colon and rectum. 2000 Academic Article GET IT
Times cited: 109
Is local excision adequate therapy for early rectal cancer?. Diseases of the colon and rectum. 2000 Academic Article GET IT
Times cited: 393
Modification of the gluteal perforator-based flap for reconstruction of the posterior vagina. 2000 GET IT
Times cited: 17
Molecular prognostic factors in rectal cancer treated by radiation and surgery. Diseases of the colon and rectum. 2000 Academic Article GET IT
Times cited: 71
Local excision of rectal cancer without adjuvant therapy: a word of caution. Annals of surgery. 2000 Academic Article GET IT
Times cited: 317
[Molecular classification of colorectal carcinoma]. Revista espanola de enfermedades digestivas. 1999 Editorial Article GET IT
Incontinence after lateral internal sphincterotomy: anatomic and functional evaluation. Diseases of the colon and rectum. 1998 Academic Article GET IT
Times cited: 93
Cutting seton versus two-stage seton fistulotomy in the surgical management of high anal fistula. The British journal of surgery. 1998 Academic Article GET IT
Times cited: 159
[Necrotizing gastroenteritis associated with inflammatory bowel disease]. Revista espanola de enfermedades digestivas. 1997 Review GET IT
Times cited: 1
Risks of the minimal access approach for laparoscopic surgery: multivariate analysis of morbidity related to umbilical trocar insertion. World journal of surgery. 1997 Academic Article GET IT
Times cited: 182
Anal fistula surgery. Factors associated with recurrence and incontinence. Diseases of the colon and rectum. 1996 Academic Article GET IT
Times cited: 423
Open vs. closed sphincterotomy for chronic anal fissure: long-term results. Diseases of the colon and rectum. 1996 Academic Article GET IT
Times cited: 198
Isoperistaltic jejunal interposition for intractable postgastrectomy alkaline reflux gastritis. Journal of the American College of Surgeons. 1995 Academic Article GET IT
Times cited: 28
The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands. The Journal of cell biology. 1993 Academic Article GET IT
Times cited: 471
Characterization of the p150,95 leukocyte integrin alpha subunit (CD11c) gene promoter. Identification of cis-acting elements. The Journal of biological chemistry. 1993 Academic Article GET IT
Times cited: 61
ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18). The Journal of cell biology. 1990 Academic Article GET IT
Times cited: 783
Genomic structure of an integrin alpha subunit, the leukocyte p150,95 molecule. The Journal of biological chemistry. 1990 Academic Article GET IT
Times cited: 51
Coagulation increases neutrophil CR1 and CR3 expression: primary role for platelet-derived growth factor. The Journal of laboratory and clinical medicine. 1989 Academic Article GET IT
Times cited: 6
Structure and regulation of the leukocyte adhesion receptor LFA-1 and its counterreceptors, ICAM-1 and ICAM-2. Cold Spring Harbor symposia on quantitative biology. 1989 Academic Article GET IT
Times cited: 27
Neutrophil CR3 induction by platelet supernatants is due to platelet-derived growth factor. Surgery. 1988 Academic Article GET IT
Times cited: 9
Coagulation augments neutrophil C3b receptors via formation of a protein(s) unrelated to fibrinolysis or C5 activation. Archives of surgery (Chicago, Ill. : 1960). 1988 Academic Article GET IT
Times cited: 2

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Background

education and training

Ph.D., Universidad Complutense de Madrid (Spain) 1990
M.D., Universidad Complutense Faculty of Medicine (Spain) 1979

Contact

full name

Julio Garcia-Aguilar

VIVO Weill Cornell Medical College

Julio Garcia-Aguilar Professor of Surgery

Publications

selected publications

Background

education and training

Contact

full name