Suhre, Karsten

Publications

Sort by

Co-Author Network

selected publications

Systemic Markers of Lung Function and FEV₁ Decline across Diverse Cohorts. Annals of the American Thoracic Society. 2023 Academic Article GET IT
Identification of candidate metabolite biomarkers for metabolic syndrome and its five components in population-based human cohorts. Cardiovascular diabetology. 2023 Academic Article GET IT
Characterization of exercise-induced hemolysis in endurance horses. Frontiers in veterinary science. 2023 Academic Article GET IT
Times cited: 43
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nature genetics. 2023 Review GET IT
Times cited: 2
Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations. Human molecular genetics. 2023 Academic Article GET IT
Urine-based multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS. Molecular medicine (Cambridge, Mass.). 2023 Academic Article GET IT
Times cited: 1
The Genetic Spectrum of Maturity-Onset Diabetes of the Young (MODY) in Qatar, a Population-Based Study. International journal of molecular sciences. 2022 Academic Article GET IT
Metabolic and proteomic signatures of type 2 diabetes subtypes in an Arab population. Nature communications. 2022 Academic Article GET IT
Times cited: 3
Identification of PCSK9-like human gene knockouts using metabolomics, proteomics, and whole-genome sequencing in a consanguineous population. Cell genomics. 2022 Academic Article GET IT
Times cited: 1695
Rare and common genetic determinants of metabolic individuality and their effects on human health. Nature medicine. 2022 Academic Article GET IT
Times cited: 9
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease. Communications biology. 2022 Academic Article GET IT
Times cited: 5
First mitochondrial genome-wide association study with metabolomics. Human molecular genetics. 2022 Academic Article GET IT
Dynamic patterns of postprandial metabolic responses to three dietary challenges. Frontiers in nutrition. 2022 Academic Article GET IT
Times cited: 189
Multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS. PLoS pathogens. 2022 Academic Article GET IT
Times cited: 6
Machine learning integration of multimodal data identifies key features of blood pressure regulation. EBioMedicine. 2022 Academic Article GET IT
Times cited: 3
Development and characterization of microsatellite primers for Triops granarius (Branchiopoda: Notostraca) using MiSeq technology. Molecular biology reports. 2022 Academic Article GET IT
Multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS. medRxiv : the preprint server for health sciences. 2022 Article GET IT
Times cited: 1081
Urine-based multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS. medRxiv : the preprint server for health sciences. 2022 Article GET IT
Times cited: 11
Dynamics and determinants of human plasma bile acid profiles during dietary challenges. Frontiers in nutrition. 2022 Academic Article GET IT
Times cited: 383
Variational autoencoders learn transferrable representations of metabolomics data. Communications biology. 2022 Academic Article GET IT
Times cited: 3
Cross-Sectional Blood Metabolite Markers of Hypertension: A Multicohort Analysis of 44,306 Individuals from the COnsortium of METabolomics Studies. Metabolites. 2022 Academic Article GET IT
Times cited: 69
Integrative metabolomic and proteomic signatures define clinical outcomes in severe COVID-19. iScience. 2022 Academic Article GET IT
Times cited: 17082
Detection of infiltrating fibroblasts by single-cell transcriptomics in human kidney allografts. PloS one. 2022 Academic Article GET IT
Times cited: 4
Ratios of Acetaminophen Metabolites Identify New Loci of Pharmacogenetic Relevance in a Genome-Wide Association Study. Metabolites. 2022 Academic Article GET IT
Times cited: 66
Proteomic Analysis of Plasma Markers in Patients Maintained on Antipsychotics: Comparison to Patients Off Antipsychotics and Normal Controls. Frontiers in psychiatry. 2022 Academic Article GET IT
Times cited: 30
Matching Drug Metabolites from Non-Targeted Metabolomics to Self-Reported Medication in the Qatar Biobank Study. Metabolites. 2022 Academic Article GET IT
Times cited: 974
TIGER: technical variation elimination for metabolomics data using ensemble learning architecture. Briefings in bioinformatics. 2022 Academic Article GET IT
Times cited: 5
Qatar genome: Insights on genomics from the Middle East. Human mutation. 2022 Academic Article GET IT
Times cited: 17
maplet: an extensible R toolbox for modular and reproducible metabolomics pipelines. Bioinformatics (Oxford, England). 2022 Academic Article GET IT
Times cited: 8
Identification of Robust Protein Associations With COVID-19 Disease Based on Five Clinical Studies. Frontiers in immunology. 2022 Academic Article GET IT
Times cited: 10
Advancing Cancer Treatment by Targeting Glutamine Metabolism-A Roadmap. Cancers. 2022 Review GET IT
Times cited: 67
Epigenetic scores for the circulating proteome as tools for disease prediction. eLife. 2022 Academic Article GET IT
Times cited: 10
SGI: automatic clinical subgroup identification in omics datasets. Bioinformatics (Oxford, England). 2022 Academic Article GET IT
Systems biology analysis of human genomes points to key pathways conferring spina bifida risk. Proceedings of the National Academy of Sciences of the United States of America. 2021 Academic Article GET IT
Times cited: 5
Defining the landscape of metabolic dysregulations in cancer metastasis. Clinical & experimental metastasis. 2021 Academic Article GET IT
Times cited: 3
Proteome-wide associations with short- and long-term weight loss and regain after Roux-en-Y gastric bypass surgery. Obesity (Silver Spring, Md.). 2021 Academic Article GET IT
Times cited: 2
Metabolic and Metabo-Clinical Signatures of T2D, Obesity, Retinopathy and Dyslipidemia. Diabetes. 2021 Academic Article GET IT
The Proteomic Signature of Recombinant Growth Hormone in Recreational Athletes. Journal of the Endocrine Society. 2021 Academic Article GET IT
Times cited: 2
Kidney Allograft Function Is a Confounder of Urine Metabolite Profiles in Kidney Allograft Recipients. Metabolites. 2021 Academic Article GET IT
Times cited: 974
Robust Huber-LASSO for improved prediction of protein, metabolite and gene expression levels relying on individual genotype data. Briefings in bioinformatics. 2021 Academic Article GET IT
Times cited: 6
Salivary metabolites associated with a 5-year tooth loss identified in a population-based setting. BMC medicine. 2021 Academic Article GET IT
Times cited: 5
Plasma Proteomics of Renal Function: A Transethnic Meta-Analysis and Mendelian Randomization Study. Journal of the American Society of Nephrology : JASN. 2021 Academic Article GET IT
Times cited: 9
Connecting the epigenome, metabolome and proteome for a deeper understanding of disease. Journal of internal medicine. 2021 Review GET IT
Times cited: 2
Metabolic syndrome and the plasma proteome: from association to causation. Cardiovascular diabetology. 2021 Academic Article GET IT
Times cited: 10
Evidence of Recombination Suppression Blocks on the Y Chromosome of Date Palm (Phoenix dactylifera). Frontiers in plant science. 2021 Academic Article GET IT
Times cited: 469
Deep sequencing of DNA from urine of kidney allograft recipients to estimate donor/recipient-specific DNA fractions. PloS one. 2021 Academic Article GET IT
Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19. medRxiv : the preprint server for health sciences. 2021 Article GET IT
Genome-wide investigation identifies a rare copy-number variant burden associated with human spina bifida. Genetics in medicine : official journal of the American College of Medical Genetics. 2021 Academic Article GET IT
Times cited: 5
Revealing the role of the human blood plasma proteome in obesity using genetic drivers. Nature communications. 2021 Academic Article GET IT
Times cited: 23
Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes. Antioxidants (Basel, Switzerland). 2021 Academic Article GET IT
Times cited: 453
Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Nature communications. 2021 Academic Article GET IT
Times cited: 26
Validation of Candidate Phospholipid Biomarkers of Chronic Kidney Disease in Hyperglycemic Individuals and Their Organ-Specific Exploration in Leptin Receptor-Deficient db/db Mouse. Metabolites. 2021 Academic Article GET IT
Times cited: 3479
Metabolic Predictors of Equine Performance in Endurance Racing. Metabolites. 2021 Academic Article GET IT
Times cited: 40
A strategy to incorporate prior knowledge into correlation network cutoff selection. Nature communications. 2020 Academic Article GET IT
Times cited: 9
The metabolic footprint of compromised insulin sensitivity under fasting and hyperinsulinemic-euglycemic clamp conditions in an Arab population. Scientific reports. 2020 Academic Article GET IT
Times cited: 5
Machine Learning Approaches Reveal Metabolic Signatures of Incident Chronic Kidney Disease in Individuals With Prediabetes and Type 2 Diabetes. Diabetes. 2020 Academic Article GET IT
Times cited: 15
Deciphering the Plasma Proteome of Type 2 Diabetes. Diabetes. 2020 Academic Article GET IT
Times cited: 19
Genetics meets proteomics: perspectives for large population-based studies. Nature reviews. Genetics. 2020 Review GET IT
Times cited: 106
Identification of genetic variants controlling RNA editing and their effect on RNA structure stabilization. European journal of human genetics : EJHG. 2020 Academic Article GET IT
Times cited: 4
Metabolic Signatures of Tumor Responses to Doxorubicin Elucidated by Metabolic Profiling in Ovo. Metabolites. 2020 Academic Article GET IT
Times cited: 218
Author Correction: Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance. Scientific reports. 2020 Article GET IT
Proteome-wide assessment of diabetes mellitus in Qatari identifies IGFBP-2 as a risk factor already with early glycaemic disturbances. Archives of biochemistry and biophysics. 2020 Academic Article GET IT
Times cited: 4
Author Correction: Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects. Scientific reports. 2020 Article GET IT
Times cited: 2
Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism. Frontiers in genetics. 2020 Academic Article GET IT
Times cited: 8
Deletion of beta-fructofuranosidase (invertase) genes is associated with sucrose content in Date Palm fruit. Plant direct. 2020 Academic Article GET IT
Times cited: 58
Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes. Diabetes. 2020 Academic Article GET IT
Times cited: 47
Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels. Human molecular genetics. 2020 Academic Article GET IT
Times cited: 10
Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects. Scientific reports. 2020 Academic Article GET IT
Times cited: 47
Urinary cell transcriptomics and acute rejection in human kidney allografts. JCI insight. 2020 Academic Article GET IT
Times cited: 19
Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans. Nature genetics. 2020 Academic Article GET IT
Times cited: 60
Epigenetics meets proteomics in an epigenome-wide association study with circulating blood plasma protein traits. Nature communications. 2020 Academic Article GET IT
Times cited: 34
Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance. Scientific reports. 2019 Academic Article GET IT
Times cited: 20
Metabolomic profiling identifies novel associations with Electrolyte and Acid-Base Homeostatic patterns. Scientific reports. 2019 Academic Article GET IT
Times cited: 5
Alterations in long noncoding RNAs in women with and without polycystic ovarian syndrome. Clinical endocrinology. 2019 Academic Article GET IT
Times cited: 14
Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies. PLoS genetics. 2019 Academic Article GET IT
Times cited: 17
A Systems-level Characterization of the Differentiation of Human Embryonic Stem Cells into Mesenchymal Stem Cells. Molecular & cellular proteomics : MCP. 2019 Academic Article GET IT
Times cited: 11
Association of childhood traumatization and neuropsychiatric outcomes with altered plasma micro RNA-levels. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2019 Academic Article GET IT
Times cited: 16
Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome. Metabolites. 2019 Academic Article GET IT
Times cited: 109
Novel subpopulations in date palm (Phoenix dactylifera) identified by population-wide organellar genome sequencing. BMC genomics. 2019 Academic Article GET IT
Times cited: 13
Defining the genetic control of human blood plasma N-glycome using genome-wide association study. Human molecular genetics. 2019 Academic Article GET IT
Times cited: 31
Characterization of Bulk Phosphatidylcholine Compositions in Human Plasma Using Side-Chain Resolving Lipidomics. Metabolites. 2019 Academic Article GET IT
Times cited: 29
Metabolic profiling of elite athletes with different cardiovascular demand. Scandinavian journal of medicine & science in sports. 2019 Academic Article GET IT
Times cited: 21
The Saliva Metabolome in Association to Oral Health Status. Journal of dental research. 2019 Academic Article GET IT
Times cited: 53
Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population. Metabolites. 2019 Academic Article GET IT
Times cited: 2338
Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS. Frontiers in endocrinology. 2019 Academic Article GET IT
Times cited: 78
MoDentify: phenotype-driven module identification in metabolomics networks at different resolutions. Bioinformatics (Oxford, England). 2019 Academic Article GET IT
Times cited: 11
ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci. Nucleic acids research. 2019 Academic Article GET IT
Times cited: 48
Metabolic and proteomic signatures of hypoglycaemia in type 2 diabetes. Diabetes, obesity & metabolism. 2018 Academic Article GET IT
Times cited: 14
Genotyping-by-sequencing identifies date palm clone preference in agronomics of the State of Qatar. PloS one. 2018 Academic Article GET IT
Times cited: 4
Author Correction: Genus-wide sequencing support a two-locus model for sex-determination in Phoenix. Nature communications. 2018 Academic Article GET IT
Times cited: 2
Genus-wide sequencing supports a two-locus model for sex-determination in Phoenix. Nature communications. 2018 Academic Article GET IT
Times cited: 62
Metabolomics profiling of xenobiotics in elite athletes: relevance to supplement consumption. Journal of the International Society of Sports Nutrition. 2018 Academic Article GET IT
Times cited: 28
Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies. Metabolomics : Official journal of the Metabolomic Society. 2018 Academic Article GET IT
Times cited: 94
Author Correction: Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nature communications. 2018 Academic Article GET IT
Times cited: 3
Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nature communications. 2018 Academic Article GET IT
Times cited: 130
Ldlr^-^/^- and ApoE^-^/^- mice better mimic the human metabolite signature of increased carotid intima media thickness compared to other animal models of cardiovascular disease. Atherosclerosis. 2018 Academic Article GET IT
Times cited: 11
Genomic atlas of the human plasma proteome. Nature. 2018 Academic Article GET IT
Times cited: 650
Accelerated lipid catabolism and autophagy are cancer survival mechanisms under inhibited glutaminolysis. Cancer letters. 2018 Academic Article GET IT
Times cited: 40
Single nucleotide variant counts computed from RNA sequencing and cellular traffic into human kidney allografts. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2018 Academic Article GET IT
Times cited: 9
A comprehensive metabolomic data set of date palm fruit. Data in brief. 2018 Academic Article GET IT
Times cited: 11
Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation. Human molecular genetics. 2018 Academic Article GET IT
Times cited: 22
Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population. Nature communications. 2018 Academic Article GET IT
Times cited: 41
A pilot study comparing the metabolic profiles of elite-level athletes from different sporting disciplines. Sports medicine - open. 2018 Academic Article GET IT
Times cited: 97
From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function. Scientific reports. 2017 Academic Article GET IT
Times cited: 26
Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives. Scientific reports. 2017 Academic Article GET IT
Times cited: 40
Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study. Diabetologia. 2017 Academic Article GET IT
Times cited: 24
pulver: an R package for parallel ultra-rapid p-value computation for linear regression interaction terms. BMC bioinformatics. 2017 Academic Article GET IT
Times cited: 1
Phenotype-driven identification of modules in a hierarchical map of multifluid metabolic correlations. NPJ systems biology and applications. 2017 Academic Article GET IT
Times cited: 50
Advanced glycation end products among patients maintained on antipsychotics. International clinical psychopharmacology. 2017 Academic Article GET IT
Times cited: 1
Large Scale Metabolic Profiling identifies Novel Steroids linked to Rheumatoid Arthritis. Scientific reports. 2017 Academic Article GET IT
Times cited: 21
Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes. Scientific reports. 2017 Academic Article GET IT
Times cited: 11
The association between various smoking behaviors, cotinine biomarkers and skin autofluorescence, a marker for advanced glycation end product accumulation. PloS one. 2017 Academic Article GET IT
Times cited: 31
Sex-specific metabolic profiles of androgens and its main binding protein SHBG in a middle aged population without diabetes. Scientific reports. 2017 Academic Article GET IT
Times cited: 11
Response to Comment on Adam et al. Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues. Diabetes 2016;65:3776-3785. Diabetes. 2017 Letter GET IT
Erratum: Connecting genetic risk to disease end points through the human blood plasma proteome. Nature communications. 2017 Academic Article GET IT
Times cited: 9
Metabolic network failures in Alzheimer's disease: A biochemical road map. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2017 Academic Article GET IT
Times cited: 252
Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers. Heart (British Cardiac Society). 2017 Academic Article GET IT
Times cited: 29
Connecting genetic risk to disease end points through the human blood plasma proteome. Nature communications. 2017 Academic Article GET IT
Times cited: 279
PopPAnTe: population and pedigree association testing for quantitative data. BMC genomics. 2017 Academic Article GET IT
Times cited: 4
Nesting of colon and ovarian cancer cells in the endothelial niche is associated with alterations in glycan and lipid metabolism. Scientific reports. 2017 Academic Article GET IT
Times cited: 23
Mutation in noncoding RNA RNU12 causes early onset cerebellar ataxia. Annals of neurology. 2017 Academic Article GET IT
Times cited: 54
Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. Human molecular genetics. 2016 Academic Article GET IT
Times cited: 83
Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects. Clinical epigenetics. 2016 Academic Article GET IT
Times cited: 8
Metabolic Fingerprints of Circulating IGF-1 and the IGF-1/IGFBP-3 Ratio: A Multifluid Metabolomics Study. The Journal of clinical endocrinology and metabolism. 2016 Academic Article GET IT
Times cited: 17
Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues. Diabetes. 2016 Academic Article GET IT
Times cited: 41
Characterization of the metabolic profile associated with serum 25-hydroxyvitamin D: a cross-sectional analysis in population-based data. International journal of epidemiology. 2016 Academic Article GET IT
Times cited: 17
Complementarity of SOMAscan to LC-MS/MS and RNA-seq for quantitative profiling of human embryonic and mesenchymal stem cells. Journal of proteomics. 2016 Academic Article GET IT
Times cited: 32
Metabolomics enables precision medicine: "A White Paper, Community Perspective". Metabolomics : Official journal of the Metabolomic Society. 2016 Academic Article GET IT
Times cited: 29
Specific Metabolic Markers Are Associated with Future Waist-Gaining Phenotype in Women. PloS one. 2016 Academic Article GET IT
Times cited: 4
Measurement of 1,5-anhydroglucitol in blood and saliva: from non-targeted metabolomics to biochemical assay. Journal of translational medicine. 2016 Academic Article GET IT
Times cited: 27
The Pharmacogenetic Footprint of ACE Inhibition: A Population-Based Metabolomics Study. PloS one. 2016 Academic Article GET IT
Times cited: 10
Genetic Influences on Metabolite Levels: A Comparison across Metabolomic Platforms. PloS one. 2016 Academic Article GET IT
Times cited: 55
Comprehensive transcriptomic and proteomic characterization of human mesenchymal stem cells reveals source specific cellular markers. Scientific reports. 2016 Academic Article GET IT
Times cited: 90
Epigenetic associations of type 2 diabetes and BMI in an Arab population. Clinical epigenetics. 2016 Academic Article GET IT
Times cited: 92
Alterations in Lipid and Inositol Metabolisms in Two Dopaminergic Disorders. PloS one. 2016 Academic Article GET IT
Times cited: 24
Diagnostic and Prognostic Metabolites Identified for Joint Symptoms in the KORA Population. Journal of proteome research. 2016 Academic Article GET IT
Times cited: 2
Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations. Genome research. 2016 Academic Article GET IT
Times cited: 62
Metabolomics profiling reveals novel markers for leukocyte telomere length. Aging. 2016 Academic Article GET IT
Times cited: 27
Athlome Project Consortium: a concerted effort to discover genomic and other "omic" markers of athletic performance. Physiological genomics. 2015 Review GET IT
Times cited: 89
Metabolomics of dates (Phoenix dactylifera) reveals a highly dynamic ripening process accounting for major variation in fruit composition. BMC plant biology. 2015 Academic Article GET IT
Times cited: 34
Response to Comment on Xu et al. Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes. Diabetes Care 2015;38:1858-1867. Diabetes care. 2015 Letter GET IT
Times cited: 2
Copy number variations in the genome of the Qatari population. BMC genomics. 2015 Academic Article GET IT
Times cited: 8
Guest Editorial: Special issue on metabolomics. Archives of biochemistry and biophysics. 2015 Editorial Article GET IT
Times cited: 1
Associations of circulating plasma microRNAs with age, body mass index and sex in a population-based study. BMC medical genomics. 2015 Academic Article GET IT
Times cited: 123
Biochemical insights from population studies with genetics and metabolomics. Archives of biochemistry and biophysics. 2015 Review GET IT
Times cited: 41
A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population. Journal of the American Society of Nephrology : JASN. 2015 Academic Article GET IT
Times cited: 138
Non-truncating LIFR mutation: causal for prominent congenital pain insensitivity phenotype with progressive vertebral destruction?. Clinical genetics. 2015 Academic Article GET IT
Times cited: 7
Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis. Archives of biochemistry and biophysics. 2015 Academic Article GET IT
Times cited: 47
Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality. PLoS genetics. 2015 Academic Article GET IT
Times cited: 68
Erratum to: A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control. Diabetologia. 2015 Article GET IT
MetaRNA-Seq: An Interactive Tool to Browse and Annotate Metadata from RNA-Seq Studies. BioMed research international. 2015 Academic Article GET IT
Times cited: 4
Type 2 diabetes is associated with postprandial amino acid measures. Archives of biochemistry and biophysics. 2015 Academic Article GET IT
Times cited: 24
Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes. Diabetes care. 2015 Academic Article GET IT
Times cited: 94
Gender-specific pathway differences in the human serum metabolome. Metabolomics : Official journal of the Metabolomic Society. 2015 Academic Article GET IT
Times cited: 239
Metabolic signatures differentiate ovarian from colon cancer cell lines. Journal of translational medicine. 2015 Academic Article GET IT
Times cited: 31
Genetics of human metabolism: an update. Human molecular genetics. 2015 Review GET IT
Times cited: 89
The Human Blood Metabolome-Transcriptome Interface. PLoS genetics. 2015 Academic Article GET IT
Times cited: 71
Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. Nature communications. 2015 Review GET IT
Times cited: 125
A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control. Diabetologia. 2015 Academic Article GET IT
Times cited: 64
Urine Metabolite Profiles Predictive of Human Kidney Allograft Status. Journal of the American Society of Nephrology : JASN. 2015 Academic Article GET IT
Times cited: 49
Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension (Dallas, Tex. : 1979). 2015 Academic Article GET IT
Times cited: 81
A Genome-Wide Survey of Date Palm Cultivars Supports Two Major Subpopulations in Phoenix dactylifera. G3 (Bethesda, Md.). 2015 Academic Article GET IT
Times cited: 39
Systems biology analysis merging phenotype, metabolomic and genomic data identifies Non-SMC Condensin I Complex, Subunit G (NCAPG) and cellular maintenance processes as major contributors to genetic variability in bovine feed efficiency. PloS one. 2015 Academic Article GET IT
Times cited: 28
Multi-omic signature of body weight change: results from a population-based cohort study. BMC medicine. 2015 Academic Article GET IT
Times cited: 50
Bipolar disorders in the Arab world: a critical review. Annals of the New York Academy of Sciences. 2015 Review GET IT
Times cited: 4
Association of DNA methylation with age, gender, and smoking in an Arab population. Clinical epigenetics. 2015 Academic Article GET IT
Times cited: 955
Elevated HbA1c levels in individuals not diagnosed with type 2 diabetes in Qatar: a pilot study. Qatar medical journal. 2014 Academic Article GET IT
Times cited: 2
Network-based approach for analyzing intra- and interfluid metabolite associations in human blood, urine, and saliva. Journal of proteome research. 2014 Academic Article GET IT
Times cited: 34
DI-ICR-FT-MS-based high-throughput deep metabotyping: a case study of the Caenorhabditis elegans-Pseudomonas aeruginosa infection model. Analytical and bioanalytical chemistry. 2014 Academic Article GET IT
Times cited: 23
SNiPA: an interactive, genetic variant-centered annotation browser. Bioinformatics (Oxford, England). 2014 Academic Article GET IT
Times cited: 188
Evaluation of SNP calling using single and multiple-sample calling algorithms by validation against array base genotyping and Mendelian inheritance. BMC research notes. 2014 Academic Article GET IT
Times cited: 11
Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice. Diabetes. 2014 Academic Article GET IT
Times cited: 32
On the potential of models for location and scale for genome-wide DNA methylation data. BMC bioinformatics. 2014 Academic Article GET IT
Times cited: 13
Novel genetic associations with serum level metabolites identified by phenotype set enrichment analyses. Human molecular genetics. 2014 Academic Article GET IT
Times cited: 24
Metabolomics of Ramadan fasting: an opportunity for the controlled study of physiological responses to food intake. Journal of translational medicine. 2014 Academic Article GET IT
Times cited: 23
Metabolic profiling in diabetes. The Journal of endocrinology. 2014 Review GET IT
Times cited: 77
Cohort profile: Greifswald approach to individualized medicine (GANI_MED). Journal of translational medicine. 2014 Academic Article GET IT
Times cited: 44
Where cancer genomics should go next: a clinician's perspective. Human molecular genetics. 2014 Review GET IT
Times cited: 14
An atlas of genetic influences on human blood metabolites. Nature genetics. 2014 Academic Article GET IT
Times cited: 737
Metabolomics approach reveals effects of antihypertensives and lipid-lowering drugs on the human metabolism. European journal of epidemiology. 2014 Academic Article GET IT
Times cited: 59
Mapping the genetic architecture of gene regulation in whole blood. PloS one. 2014 Academic Article GET IT
Times cited: 28
A first genetic map of date palm (Phoenix dactylifera) reveals long-range genome structure conservation in the palms. BMC genomics. 2014 Academic Article GET IT
Times cited: 66
Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids. Genome medicine. 2014 Academic Article GET IT
Times cited: 147
Mesenchymal cell interaction with ovarian cancer cells induces a background dependent pro-metastatic transcriptomic profile. Journal of translational medicine. 2014 Academic Article GET IT
Times cited: 25
Long term conservation of human metabolic phenotypes and link to heritability. Metabolomics : Official journal of the Metabolomic Society. 2014 Academic Article GET IT
Times cited: 21
Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms. Cell. 2014 Academic Article GET IT
Times cited: 95
Increased amino acids levels and the risk of developing of hypertriglyceridemia in a 7-year follow-up. Journal of endocrinological investigation. 2014 Academic Article GET IT
Times cited: 32
1,5-Anhydroglucitol in saliva is a noninvasive marker of short-term glycemic control. The Journal of clinical endocrinology and metabolism. 2014 Academic Article GET IT
Times cited: 70
Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles. BMC genomics. 2013 Academic Article GET IT
Times cited: 15
A systems biology approach using metabolomic data reveals genes and pathways interacting to modulate divergent growth in cattle. BMC genomics. 2013 Academic Article GET IT
Times cited: 53
Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits. Human molecular genetics. 2013 Academic Article GET IT
Times cited: 144
Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach. Diabetes. 2013 Academic Article GET IT
Times cited: 300
Metabolite profiling reveals new insights into the regulation of serum urate in humans. Metabolomics : Official journal of the Metabolomic Society. 2013 Academic Article GET IT
Times cited: 263
Associations between thyroid hormones and serum metabolite profiles in an euthyroid population. Metabolomics : Official journal of the Metabolomic Society. 2013 Academic Article GET IT
Times cited: 1001
Metabolomic markers reveal novel pathways of ageing and early development in human populations. International journal of epidemiology. 2013 Review GET IT
Times cited: 195
Alcohol-induced metabolomic differences in humans. Translational psychiatry. 2013 Academic Article GET IT
Times cited: 69
Metabolites associate with kidney function decline and incident chronic kidney disease in the general population. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2013 Academic Article GET IT
Times cited: 93
Ethnic and gender differences in advanced glycation end products measured by skin auto-fluorescence. Dermato-endocrinology. 2013 Academic Article GET IT
Times cited: 459
Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study. BMC medicine. 2013 Academic Article GET IT
Times cited: 90
Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma. Allergy. 2013 Academic Article GET IT
Times cited: 64
Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma. Genome medicine. 2013 Academic Article GET IT
Times cited: 39
Metabolomic profiles in individuals with negative affectivity and social inhibition: a population-based study of Type D personality. Psychoneuroendocrinology. 2012 Academic Article GET IT
Times cited: 29
Metabolomics platforms for genome wide association studies--linking the genome to the metabolome. Current opinion in biotechnology. 2012 Review GET IT
Times cited: 82
Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information. PLoS genetics. 2012 Academic Article GET IT
Times cited: 134
Targeted metabolomics profiles are strongly correlated with nutritional patterns in women. Metabolomics : Official journal of the Metabolomic Society. 2012 Academic Article GET IT
Times cited: 26
Childhood obesity is associated with changes in the serum metabolite profile. Obesity facts. 2012 Academic Article GET IT
Times cited: 128
Genetic variation in metabolic phenotypes: study designs and applications. Nature reviews. Genetics. 2012 Review GET IT
Times cited: 140
Comparison of metabolic profiles of acutely ill and short-term weight recovered patients with anorexia nervosa reveals alterations of 33 out of 163 metabolites. Journal of psychiatric research. 2012 Academic Article GET IT
Times cited: 23
Human serum metabolic profiles are age dependent. Aging cell. 2012 Academic Article GET IT
Times cited: 220
Bayesian independent component analysis recovers pathway signatures from blood metabolomics data. Journal of proteome research. 2012 Academic Article GET IT
Times cited: 23
MassTRIX reloaded: combined analysis and visualization of transcriptome and metabolome data. PloS one. 2012 Academic Article GET IT
Times cited: 78
Body fat free mass is associated with the serum metabolite profile in a population-based study. PloS one. 2012 Academic Article GET IT
Times cited: 89
On the hypothesis-free testing of metabolite ratios in genome-wide and metabolome-wide association studies. BMC bioinformatics. 2012 Academic Article GET IT
Times cited: 78
Mesenchymal cell interaction with ovarian cancer cells triggers pro-metastatic properties. PloS one. 2012 Academic Article GET IT
Times cited: 41
Changing metabolic signatures of amino acids and lipids during the prediabetic period in a pig model with impaired incretin function and reduced β-cell mass. Diabetes. 2012 Academic Article GET IT
Times cited: 43
PSEA: Phenotype Set Enrichment Analysis--a new method for analysis of multiple phenotypes. Genetic epidemiology. 2012 Academic Article GET IT
Times cited: 16
Serum metabolite concentrations and decreased GFR in the general population. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2012 Academic Article GET IT
Times cited: 85
The dynamic range of the human metabolome revealed by challenges. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2012 Academic Article GET IT
Times cited: 251
Novel biomarkers for pre-diabetes identified by metabolomics. Molecular systems biology. 2012 Academic Article GET IT
Times cited: 531
Genetic associations with lipoprotein subfractions provide information on their biological nature. Human molecular genetics. 2011 Academic Article GET IT
Times cited: 24
High TCR diversity ensures optimal function and homeostasis of Foxp3+ regulatory T cells. European journal of immunology. 2011 Academic Article GET IT
Times cited: 76
Role of medium- and short-chain L-3-hydroxyacyl-CoA dehydrogenase in the regulation of body weight and thermogenesis. Endocrinology. 2011 Academic Article GET IT
Times cited: 33
A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection. PLoS genetics. 2011 Academic Article GET IT
Times cited: 107
Human metabolic individuality in biomedical and pharmaceutical research. Nature. 2011 Academic Article GET IT
Times cited: 784
Discovery of sexual dimorphisms in metabolic and genetic biomarkers. PLoS genetics. 2011 Academic Article GET IT
Times cited: 273
Differences between human plasma and serum metabolite profiles. PloS one. 2011 Academic Article GET IT
Times cited: 326
A genome-wide association study of metabolic traits in human urine. Nature genetics. 2011 Academic Article GET IT
Times cited: 200
Identification of a potential biomarker for FABP4 inhibition: the power of lipidomics in preclinical drug testing. Journal of biomolecular screening. 2011 Academic Article GET IT
Times cited: 26
Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data. BMC systems biology. 2011 Academic Article GET IT
Times cited: 217
Questionnaire-based self-reported nutrition habits associate with serum metabolism as revealed by quantitative targeted metabolomics. European journal of epidemiology. 2010 Academic Article GET IT
Times cited: 72
MIPS: curated databases and comprehensive secondary data resources in 2010. Nucleic acids research. 2010 Academic Article GET IT
Times cited: 67
Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. PloS one. 2010 Academic Article GET IT
Times cited: 467
metaP-server: a web-based metabolomics data analysis tool. Journal of biomedicine & biotechnology. 2010 Academic Article GET IT
Times cited: 60
Mouse phenotyping. Methods (San Diego, Calif.). 2010 Review GET IT
Times cited: 114
Metabolomic profiles indicate distinct physiological pathways affected by two loci with major divergent effect on Bos taurus growth and lipid deposition. Physiological genomics. 2010 Academic Article GET IT
Times cited: 57
A genome-wide perspective of genetic variation in human metabolism. Nature genetics. 2009 Academic Article GET IT
Times cited: 523
Variation in the human lipidome associated with coffee consumption as revealed by quantitative targeted metabolomics. Molecular nutrition & food research. 2009 Academic Article GET IT
Times cited: 49
Characteristics of mutants designed to incorporate a new ion pair into the structure of a cold adapted subtilisin-like serine proteinase. Biochimica et biophysica acta. 2008 Academic Article GET IT
Times cited: 28
Metabolic profiling reveals distinct variations linked to nicotine consumption in humans--first results from the KORA study. PloS one. 2008 Academic Article GET IT
Times cited: 96
Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS genetics. 2008 Academic Article GET IT
Times cited: 559
Putative gene promoter sequences in the chlorella viruses. Virology. 2008 Academic Article GET IT
Times cited: 12
MassTRIX: mass translator into pathways. Nucleic acids research. 2008 Academic Article GET IT
Times cited: 176
Bioinformatics analysis of targeted metabolomics--uncovering old and new tales of diabetic mice under medication. Endocrinology. 2008 Academic Article GET IT
Times cited: 107
Reductive genome evolution from the mother of Rickettsia. PLoS genetics. 2007 Academic Article GET IT
Times cited: 144
Inference of gene function based on gene fusion events: the rosetta-stone method. Methods in molecular biology (Clifton, N.J.). 2007 Academic Article GET IT
Times cited: 19
NORMA: a tool for flexible fitting of high-resolution protein structures into low-resolution electron-microscopy-derived density maps. Acta crystallographica. Section D, Biological crystallography. 2006 Academic Article GET IT
Times cited: 103
Isolation, characterization, and bioinformatic analysis of calmodulin-binding protein cmbB reveals a novel tandem IP22 repeat common to many Dictyostelium and Mimivirus proteins. Biochemical and biophysical research communications. 2006 Academic Article GET IT
Times cited: 22
Estimation of prokaryote genomic DNA G+C content by sequencing universally conserved genes. International journal of systematic and evolutionary microbiology. 2006 Academic Article GET IT
Times cited: 39
Determination of strongly overlapping signaling activity from microarray data. BMC bioinformatics. 2006 Academic Article GET IT
Times cited: 20
Mimivirus and the emerging concept of "giant" virus. Virus research. 2006 Review GET IT
Times cited: 137
GFscore: a general nonlinear consensus scoring function for high-throughput docking. Journal of chemical information and modeling. 2006 Academic Article GET IT
Times cited: 52
Conformational flexibility of Mycobacterium tuberculosis thioredoxin reductase: crystal structure and normal-mode analysis. Acta crystallographica. Section D, Biological crystallography. 2005 Academic Article GET IT
Times cited: 44
Gene and genome duplication in Acanthamoeba polyphaga Mimivirus. Journal of virology. 2005 Academic Article GET IT
Times cited: 70
Phydbac "Gene Function Predictor": a gene annotation tool based on genomic context analysis. BMC bioinformatics. 2005 Academic Article GET IT
Times cited: 47
Mimivirus gene promoters exhibit an unprecedented conservation among all eukaryotes. Proceedings of the National Academy of Sciences of the United States of America. 2005 Academic Article GET IT
Times cited: 63
Discovery of protein-coding palindromic repeats in Wolbachia. Trends in microbiology. 2005 Letter GET IT
Times cited: 16
Mimivirus TyrRS: preliminary structural and functional characterization of the first amino-acyl tRNA synthetase found in a virus. Acta crystallographica. Section F, Structural biology and crystallization communications. 2005 Academic Article GET IT
Times cited: 21
Bayesian decomposition analysis of bacterial phylogenomic profiles. American journal of pharmacogenomics : genomics-related research in drug development and clinical practice. 2005 Academic Article GET IT
Times cited: 2
3DCoffee: combining protein sequences and structures within multiple sequence alignments. Journal of molecular biology. 2004 Academic Article GET IT
Times cited: 263
3DCoffee@igs: a web server for combining sequences and structures into a multiple sequence alignment. Nucleic acids research. 2004 Academic Article GET IT
Times cited: 140
CaspR: a web server for automated molecular replacement using homology modelling. Nucleic acids research. 2004 Academic Article GET IT
Times cited: 80
ElNemo: a normal mode web server for protein movement analysis and the generation of templates for molecular replacement. Nucleic acids research. 2004 Academic Article GET IT
Times cited: 583
Phydbac2: improved inference of gene function using interactive phylogenomic profiling and chromosomal location analysis. Nucleic acids research. 2004 Academic Article GET IT
Times cited: 26
Set1 is required for meiotic S-phase onset, double-strand break formation and middle gene expression. The EMBO journal. 2004 Academic Article GET IT
Times cited: 105
On the potential of normal-mode analysis for solving difficult molecular-replacement problems. Acta crystallographica. Section D, Biological crystallography. 2004 Academic Article GET IT
Times cited: 96
Computing multiple sequence/structure alignments with the T-coffee package. Current protocols in bioinformatics. 2004 Academic Article GET IT
Times cited: 14
FusionDB: a database for in-depth analysis of prokaryotic gene fusion events. Nucleic acids research. 2004 Academic Article GET IT
Times cited: 56
Tropheryma whipplei Twist: a human pathogenic Actinobacteria with a reduced genome. Genome research. 2003 Academic Article GET IT
Times cited: 158
Phydbac (phylogenomic display of bacterial genes): An interactive resource for the annotation of bacterial genomes. Nucleic acids research. 2003 Academic Article GET IT
Times cited: 13
Genomic correlates of hyperthermostability, an update. The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 140
Annotation of bacterial genomes using improved phylogenomic profiles. Bioinformatics (Oxford, England). 2003 Academic Article GET IT
Times cited: 41
Structural genomics of highly conserved microbial genes of unknown function in search of new antibacterial targets. Journal of structural and functional genomics. 2003 Academic Article GET IT
Times cited: 59

more ...

less ...

Background

education and training

Ph.D., University of Toulouse (France) 1994
B.S., University of Osnabrueck (Germany) 1991

Contact

full name

Karsten Suhre

primary email

kas2049@qatar-med.cornell.edu

VIVO Weill Cornell Medical College

Karsten Suhre Professor of Physiology and Biophysics

Publications

selected publications

Background

education and training

Contact

full name

primary email