Park-Min, Kyung-Hyun

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selected publications

Metabolic reprogramming in osteoclasts. Seminars in immunopathology. 2019 Review GET IT
Times cited: 51
IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate macrophage activation. Nature communications. 2019 Academic Article GET IT
Times cited: 45
The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair. Immunity. 2019 Academic Article GET IT
Times cited: 65
Mechanisms involved in normal and pathological osteoclastogenesis. Cellular and molecular life sciences : CMLS. 2018 Review GET IT
Times cited: 62
Type I interferons and the cytokine TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation. Nature immunology. 2017 Academic Article GET IT
Times cited: 142
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF. Immunity. 2017 Academic Article GET IT
Times cited: 109
MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERRα. The Journal of clinical investigation. 2017 Academic Article GET IT
Times cited: 69
Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages. Scientific reports. 2016 Academic Article GET IT
Times cited: 21
Cutting Edge: EZH2 Promotes Osteoclastogenesis by Epigenetic Silencing of the Negative Regulator IRF8. Journal of immunology (Baltimore, Md. : 1950). 2016 Academic Article GET IT
Times cited: 49
Epigenetic regulation of bone cells. Connective tissue research. 2016 Review GET IT
Times cited: 20
Intravenous Immunoglobulin (IVIG) Attenuates TNF-Induced Pathologic Bone Resorption and Suppresses Osteoclastogenesis by Inducing A20 Expression. Journal of cellular physiology. 2016 Academic Article GET IT
Times cited: 13
Tmem178 acts in a novel negative feedback loop targeting NFATc1 to regulate bone mass. Proceedings of the National Academy of Sciences of the United States of America. 2015 Academic Article GET IT
Times cited: 24
Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Nature. 2015 Academic Article GET IT
Times cited: 358
Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation. Nature communications. 2014 Academic Article GET IT
Times cited: 93
Tumor necrosis factor α induces sustained signaling and a prolonged and unremitting inflammatory response in rheumatoid arthritis synovial fibroblasts. Arthritis and rheumatism. 2013 Academic Article GET IT
Times cited: 103
iRHOM2 is a critical pathogenic mediator of inflammatory arthritis. The Journal of clinical investigation. 2013 Academic Article GET IT
Times cited: 130
Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2013 Academic Article GET IT
Times cited: 44
ITAM-coupled receptors inhibit IFNAR signaling and alter macrophage responses to TLR4 and Listeria monocytogenes. Journal of immunology (Baltimore, Md. : 1950). 2012 Academic Article GET IT
Times cited: 23
Feedback inhibition of osteoclastogenesis during inflammation by IL-10, M-CSF receptor shedding, and induction of IRF8. Annals of the New York Academy of Sciences. 2011 Review GET IT
Times cited: 28
Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages. Nature immunology. 2011 Academic Article GET IT
Times cited: 130
Direct inhibition of human RANK+ osteoclast precursors identifies a homeostatic function of IL-1beta. Journal of immunology (Baltimore, Md. : 1950). 2010 Academic Article GET IT
Times cited: 33
Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins. Immunity. 2010 Academic Article GET IT
Times cited: 115
Interleukin-27 inhibits human osteoclastogenesis by abrogating RANKL-mediated induction of nuclear factor of activated T cells c1 and suppressing proximal RANK signaling. Arthritis and rheumatism. 2010 Academic Article GET IT
Times cited: 75
Inhibition of RANK expression and osteoclastogenesis by TLRs and IFN-gamma in human osteoclast precursors. Journal of immunology (Baltimore, Md. : 1950). 2009 Academic Article GET IT
Times cited: 127
IL-10 suppresses calcium-mediated costimulation of receptor activator NF-kappa B signaling during human osteoclast differentiation by inhibiting TREM-2 expression. Journal of immunology (Baltimore, Md. : 1950). 2009 Academic Article GET IT
Times cited: 92
Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages. Human immunology. 2009 Academic Article GET IT
Times cited: 80
Regulation of STAT pathways and IRF1 during human dendritic cell maturation by TNF-alpha and PGE2. Journal of leukocyte biology. 2008 Academic Article GET IT
Times cited: 22
TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes. Nature immunology. 2008 Academic Article GET IT
Times cited: 328
'Tuning' of type I interferon-induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages. Nature immunology. 2007 Academic Article GET IT
Times cited: 70
Apoptotic cells inhibit LPS-induced cytokine and chemokine production and IFN responses in macrophages. Human immunology. 2007 Academic Article GET IT
Times cited: 44
FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin. Immunity. 2007 Academic Article GET IT
Times cited: 137
IFN-gamma-primed macrophages exhibit increased CCR2-dependent migration and altered IFN-gamma responses mediated by Stat1. Journal of immunology (Baltimore, Md. : 1950). 2005 Academic Article GET IT
Times cited: 53
Kinetics of IL-10-induced gene expression in human macrophages. Immunobiology. 2005 Academic Article GET IT
Times cited: 22
Regulation of macrophage phenotype by long-term exposure to IL-10. Immunobiology. 2005 Academic Article GET IT
Times cited: 48
Inhibition of interleukin 10 signaling after Fc receptor ligation and during rheumatoid arthritis. The Journal of experimental medicine. 2003 Academic Article GET IT
Times cited: 62

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Background

education and training

Ph.D., Weill Cornell Graduate School of Medical Sciences 2007
M.S., Korea University (Korea) 1995
B.A., Korea University (Korea) 1993

Contact

full name

Kyung-Hyun Park-Min

primary email

kyp2001@med.cornell.edu

VIVO Weill Cornell Medical College

Kyung-Hyun Park-Min Associate Professor of Immunology in Medicine

Publications

selected publications

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Background

education and training

Contact

full name

primary email