Li, Lei

Publications

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selected publications

CD40LG-associated X-linked Hyper-IgM Syndrome (XHIGM) with pulmonary alveolar proteinosis: a case report. 2023 GET IT
Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants. The Journal of clinical investigation. 2023 Academic Article GET IT
Times cited: 2
A hybrid single cell demultiplexing strategy that increases both cell recovery rate and calling accuracy. bioRxiv : the preprint server for biology. 2023 Article GET IT
Hemagglutinin destabilization in H3N2 vaccine reference viruses skews antigenicity and prevents airborne transmission in ferrets. Science advances. 2023 Academic Article GET IT
Times cited: 1
Selecting Representative Samples From Complex Biological Datasets Using K-Medoids Clustering. Frontiers in genetics. 2022 Academic Article GET IT
Times cited: 118
Memory B cell diversity: insights for optimized vaccine design. Trends in immunology. 2022 Review GET IT
Times cited: 6
Librator: a platform for the optimized analysis, design, and expression of mutable influenza viral antigens. Briefings in bioinformatics. 2022 Academic Article GET IT
Times cited: 1
Broadly neutralizing antibodies target a haemagglutinin anchor epitope. Nature. 2021 Academic Article GET IT
Times cited: 28
Cross-Neutralization of Emerging SARS-CoV-2 Variants of Concern by Antibodies Targeting Distinct Epitopes on Spike. mBio. 2021 Academic Article GET IT
Times cited: 12
Improved integration of single-cell transcriptome and surface protein expression by LinQ-View. Cell reports methods. 2021 Academic Article GET IT
Times cited: 4
Cross neutralization of emerging SARS-CoV-2 variants of concern by antibodies targeting distinct epitopes on spike. Research square. 2021 Article GET IT
Times cited: 23
An Egg-Derived Sulfated N-Acetyllactosamine Glycan Is an Antigenic Decoy of Influenza Virus Vaccines. mBio. 2021 Academic Article GET IT
Times cited: 5
Hemolysis-associated phosphatidylserine exposure promotes polyclonal plasmablast differentiation. The Journal of experimental medicine. 2021 Academic Article GET IT
Times cited: 8
First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes. Science translational medicine. 2021 Academic Article GET IT
Times cited: 17
Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets. Immunity. 2021 Academic Article GET IT
Times cited: 54
Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity. Science translational medicine. 2021 Academic Article GET IT
Times cited: 25
Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity. PLoS pathogens. 2021 Academic Article GET IT
Times cited: 6
SARS-CoV-2 Infection Severity Is Linked to Superior Humoral Immunity against the Spike. mBio. 2021 Academic Article GET IT
Times cited: 51
Tissue Tropisms of Avian Influenza A Viruses Affect Their Spillovers from Wild Birds to Pigs. Journal of virology. 2020 Academic Article GET IT
Times cited: 5
Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses. Immunity. 2020 Academic Article GET IT
Times cited: 43
Distinct B cell subsets give rise to antigen-specific antibody responses against SARS-CoV-2. Research square. 2020 Article GET IT
Times cited: 1008
SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike. bioRxiv : the preprint server for biology. 2020 Article GET IT
Times cited: 406
Imprinting, immunodominance, and other impediments to generating broad influenza immunity. Immunological reviews. 2020 Review GET IT
Times cited: 26
HA stabilization promotes replication and transmission of swine H1N1 gamma influenza viruses in ferrets. eLife. 2020 Academic Article GET IT
Times cited: 15
Multi-task learning sparse group lasso: a method for quantifying antigenicity of influenza A(H1N1) virus using mutations and variations in glycosylation of Hemagglutinin. BMC bioinformatics. 2020 Academic Article GET IT
Times cited: 8
Emerging from the Shadow of Hemagglutinin: Neuraminidase Is an Important Target for Influenza Vaccination. Cell host & microbe. 2019 Comment GET IT
Times cited: 10
Interferon-β corrects massive gene dysregulation in multiple sclerosis: Short-term and long-term effects on immune regulation and neuroprotection. EBioMedicine. 2019 Academic Article GET IT
Times cited: 33
Aerosol Transmission of Gull-Origin Iceland Subtype H10N7 Influenza A Virus in Ferrets. Journal of virology. 2019 Academic Article GET IT
Times cited: 15
Tissue tropisms opt for transmissible reassortants during avian and swine influenza A virus co-infection in swine. PLoS pathogens. 2018 Academic Article GET IT
Times cited: 13
Imprinting of Repeated Influenza A/H3 Exposures on Antibody Quantity and Antibody Quality: Implications for Seasonal Vaccine Strain Selection and Vaccine Performance. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2018 Academic Article GET IT
Times cited: 40
Evolutionary pathway for the 2017 emergence of a novel highly pathogenic avian influenza A(H7N9) virus among domestic poultry in Tennessee, United States. Virology. 2018 Academic Article GET IT
Times cited: 4
Genetic Evidence Supports Sporadic and Independent Introductions of Subtype H5 Low-Pathogenic Avian Influenza A Viruses from Wild Birds to Domestic Poultry in North America. Journal of virology. 2018 Academic Article GET IT
Times cited: 18
Detection of Antigenic Variants of Subtype H3 Swine Influenza A Viruses from Clinical Samples. Journal of clinical microbiology. 2017 Academic Article GET IT
Times cited: 3
High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination. PloS one. 2015 Academic Article GET IT
Times cited: 27

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Research

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Funding awarded

DIVINCI: Dissection of Influenza Vaccination and Infection for Childhood Immunity awarded by National Institute of Allergy & Infectious Diseases Key Personnel 2021 - 2026

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Background

education and training

Ph.D., Xiamen University (China) 2015
M.S., Xi'an Jiaotong University (China) 2011
B.S., Xi'an Jiaotong University (China) 2009

Contact

full name

Lei Li

primary email

lel4003@med.cornell.edu

VIVO Weill Cornell Medical College

Lei Li Assistant Professor of Bioinformatics Research in Pediatrics

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email