Karajannis, Matthias

Publications

Sort by

Co-Author Network

selected publications

Sustained imaging response and hearing preservation with low-dose bevacizumab in sporadic vestibular schwannoma. 2019 GET IT
Times cited: 6
Peroxynitrite supports a metabolic reprogramming in merlin-deficient Schwann cells and promotes cell survival. The Journal of biological chemistry. 2019 Academic Article GET IT
Times cited: 5
The new kid on the block: suicide gene therapy to modulate cancer immunosurveillance for children with high-risk malignant brain tumors. Neuro-oncology. 2019 Comment GET IT
Times cited: 1
Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma. Science advances. 2018 Academic Article GET IT
Times cited: 85
Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma. Neuro-oncology. 2018 Academic Article GET IT
Times cited: 66
Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma. Nature communications. 2018 Academic Article GET IT
Times cited: 36
Heterogeneity within the PF-EPN-B ependymoma subgroup. Acta neuropathologica. 2018 Academic Article GET IT
Times cited: 68
Effect of lapatinib on meningioma growth in adults with neurofibromatosis type 2. Journal of neuro-oncology. 2018 Academic Article GET IT
Times cited: 19
2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis. American journal of medical genetics. Part A. 2018 Letter GET IT
Times cited: 13
DNA methylation-based classification of central nervous system tumours. Nature. 2018 Academic Article GET IT
Times cited: 1351
Patterns of relapse for children with localized intracranial ependymoma. Journal of neuro-oncology. 2018 Academic Article GET IT
Times cited: 14
Programmed death ligand 1 expression and tumor infiltrating lymphocytes in neurofibromatosis type 1 and 2 associated tumors. Journal of neuro-oncology. 2018 Academic Article GET IT
Times cited: 45
Pre-treatment lymphopenia and indication of tumor-induced systemic immunosuppression in medulloblastoma. Journal of neuro-oncology. 2017 Academic Article GET IT
Times cited: 15
Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2. Cell reports. 2017 Academic Article GET IT
Times cited: 65
DNA Methylation-Based Classifier for Accurate Molecular Diagnosis of Bone Sarcomas. JCO precision oncology. 2017 Academic Article GET IT
Times cited: 32
Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome. Acta neuropathologica. 2017 Academic Article GET IT
Times cited: 142
Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2017 Academic Article GET IT
Times cited: 190
Endothelium-Independent Primitive Myxoid Vascularization Creates Invertebrate-Like Channels to Maintain Blood Supply in Optic Gliomas. The American journal of pathology. 2017 Academic Article GET IT
Times cited: 2
Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis. Molecular cancer therapeutics. 2017 Academic Article GET IT
Times cited: 24
The path forward: 2015 International Children's Tumor Foundation conference on neurofibromatosis type 1, type 2, and schwannomatosis. American journal of medical genetics. Part A. 2017 Conference Paper GET IT
Times cited: 7
Rapid progression to glioblastoma in a subset of IDH-mutated astrocytomas: a genome-wide analysis. Journal of neuro-oncology. 2017 Academic Article GET IT
Times cited: 26
A novel, potentially targetable TMEM106B-BRAF fusion in pleomorphic xanthoastrocytoma. 2017 GET IT
Pediatric high-grade glioma: biologically and clinically in need of new thinking. Neuro-oncology. 2017 Review GET IT
Times cited: 227
Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway. Acta neuropathologica. 2016 Academic Article GET IT
Times cited: 144
Mutant IDH1 and thrombosis in gliomas. Acta neuropathologica. 2016 Academic Article GET IT
Times cited: 114
Pilocytic astrocytoma and glioneuronal tumor with histone H3 K27M mutation. Acta neuropathologica communications. 2016 Letter GET IT
Times cited: 66
Utility of MRI versus tumor markers for post-treatment surveillance of marker-positive CNS germ cell tumors. Journal of neuro-oncology. 2016 Academic Article GET IT
Times cited: 5
Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Academic Article GET IT
Times cited: 130
Pediatric Brain Tumors: An Update. Current problems in pediatric and adolescent health care. 2016 Review GET IT
Times cited: 28
Noncarboplatin-induced Sensorineural Hearing Loss in a Patient With an Intracranial Nongerminomatous Germ Cell Tumor. 2016 GET IT
The promise of molecular profiling of choroid plexus tumors for diagnostic and prognostic stratification: where to go from here?. Neuro-oncology. 2016 Editorial Article GET IT
New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs. Cell. 2016 Academic Article GET IT
Times cited: 556
Pediatric Brain Tumors: Innovative Genomic Information Is Transforming the Diagnostic and Clinical Landscape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2015 Review GET IT
Times cited: 162
Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups. Cancer cell. 2015 Academic Article GET IT
Times cited: 745
Neurofibromatosis-related tumors: emerging biology and therapies. Current opinion in pediatrics. 2015 Review GET IT
Times cited: 49
Recurrent ascites in a patient with low-grade astrocytoma and ventriculo-peritoneal shunt treated with the multikinase inhibitor sorafenib. 2014 GET IT
Times cited: 4
Clinical response to bevacizumab in schwannomatosis. 2014 GET IT
Times cited: 24
Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus. Cancer cell. 2014 Academic Article GET IT
Times cited: 166
Glioblastoma multiforme: State of the art and future therapeutics. Surgical neurology international. 2014 Review GET IT
Times cited: 182
Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas. Neuro-oncology. 2014 Academic Article GET IT
Times cited: 148
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations. Nature genetics. 2014 Academic Article GET IT
Times cited: 436
Phase II study of everolimus in children and adults with neurofibromatosis type 2 and progressive vestibular schwannomas. Neuro-oncology. 2013 Academic Article GET IT
Times cited: 82
Recommendations for imaging tumor response in neurofibromatosis clinical trials. Neurology. 2013 Academic Article GET IT
Times cited: 85
Activation of mTORC1/mTORC2 signaling in pediatric low-grade glioma and pilocytic astrocytoma reveals mTOR as a therapeutic target. Neuro-oncology. 2013 Academic Article GET IT
Times cited: 60
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis. The Lancet. Oncology. 2013 Academic Article GET IT
Times cited: 264
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nature genetics. 2013 Academic Article GET IT
Times cited: 560
MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2. Neuro-oncology. 2012 Academic Article GET IT
Times cited: 53
Phase II trial of lapatinib in adult and pediatric patients with neurofibromatosis type 2 and progressive vestibular schwannomas. Neuro-oncology. 2012 Academic Article GET IT
Times cited: 120
Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus. EMBO reports. 2012 Review GET IT
Times cited: 98
BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants. Journal of neuropathology and experimental neurology. 2012 Academic Article GET IT
Times cited: 135
Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2. American journal of medical genetics. Part A. 2011 Academic Article GET IT
Times cited: 87
R132H-mutation of isocitrate dehydrogenase-1 is not sufficient for HIF-1α upregulation in adult glioma. Acta neuropathologica. 2010 Letter GET IT
Times cited: 62
Prospective neuraxis MRI surveillance reveals a high risk of leptomeningeal dissemination in diffuse intrinsic pontine glioma. Journal of neuro-oncology. 2010 Academic Article GET IT
Times cited: 38
Bevacizumab in recurrent high-grade pediatric gliomas. Neuro-oncology. 2010 Academic Article GET IT
Times cited: 63
Overexpression and activation of epidermal growth factor receptor in hemangioblastomas. Journal of neuro-oncology. 2010 Academic Article GET IT
Times cited: 13
ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma. Neuro-oncology. 2010 Academic Article GET IT
Times cited: 71
Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2. Clinical cancer research : an official journal of the American Association for Cancer Research. 2009 Conference Paper GET IT
Times cited: 63
Synchronous mixed germ cell tumor of the pineal gland and suprasellar region with a predominant angiomatous component: a diagnostic challenge. 2008 GET IT
Times cited: 10
Treatment of pediatric brain tumors. Journal of cellular physiology. 2008 Review GET IT
Times cited: 52
The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death. Blood. 2007 Academic Article GET IT
Times cited: 65
Treatment-related myelodysplastic syndrome after chemotherapy for childhood low-grade astrocytoma. Journal of pediatric hematology/oncology. 2006 Letter GET IT
Times cited: 1
Activation of FGFR1beta signaling pathway promotes survival, migration and resistance to chemotherapy in acute myeloid leukemia cells. Leukemia. 2006 Academic Article GET IT
Times cited: 45
Fetal stromal-dependent paracrine and intracrine vascular endothelial growth factor-a/vascular endothelial growth factor receptor-1 signaling promotes proliferation and motility of human primary myeloma cells. Cancer research. 2005 Academic Article GET IT
Times cited: 61
Epstein-Barr virus infection in Western European pediatric non-Hodgkin lymphomas. Blood. 2003 Letter GET IT
Times cited: 18
Strict lymphotropism of Epstein-Barr virus during acute infectious mononucleosis in nonimmunocompromised individuals. Blood. 1997 Academic Article GET IT
Times cited: 70

more ...

less ...

Background

education and training

M.S., New York University School of Medicine 2009
M.D., Free University of Berlin (Germany) 1997

Contact

full name

Matthias Karajannis

VIVO Weill Cornell Medical College

Matthias Karajannis Professor of Pediatrics

Publications

selected publications

Background

education and training

Contact

full name