Corley, Michael

Publications

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selected publications

Distinct mucosal and systemic immunological characteristics in transgender women potentially relating to HIV acquisition. JCI insight. 2023 Academic Article GET IT
Multiplex Analysis of Cytokines and Chemokines in Persons Aging With or Without HIV. AIDS research and human retroviruses. 2023 Academic Article GET IT
The impacts of social determinants of health and cardiometabolic factors on cognitive and functional aging in Colombian underserved populations. GeroScience. 2023 Academic Article GET IT
Times cited: 1
Multiplex analysis of cytokines and chemokines in persons aging with or without HIV. bioRxiv : the preprint server for biology. 2023 Article GET IT
Neuropilin-1 Mediates SARS-CoV-2 Infection of Astrocytes in Brain Organoids, Inducing Inflammation Leading to Dysfunction and Death of Neurons. mBio. 2022 Academic Article GET IT
Times cited: 8
A machine learning approach utilizing DNA methylation as an accurate classifier of COVID-19 disease severity. Scientific reports. 2022 Academic Article GET IT
Times cited: 2
Mucosal-homing natural killer cells are associated with aging in persons living with HIV. Cell reports. Medicine. 2022 Academic Article GET IT
Times cited: 2
Shifts in the immunoepigenomic landscape of monocytes in response to a diabetes-specific social support intervention: a pilot study among Native Hawaiian adults with diabetes. Clinical epigenetics. 2022 Academic Article GET IT
HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART. JCI insight. 2022 Academic Article GET IT
Times cited: 6
Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera. Nature communications. 2022 Academic Article GET IT
Times cited: 7
Longitudinal Study of DNA Methylation and Epigenetic Clocks Prior to and Following Test-Confirmed COVID-19 and mRNA Vaccination. Frontiers in genetics. 2022 Academic Article GET IT
Times cited: 122
Suppression of human and simian immunodeficiency virus replication with the CCR5-specific antibody Leronlimab in two species. PLoS pathogens. 2022 Academic Article GET IT
Times cited: 5
Candidate Epigenetic Biomarker of Cognitive Trajectory: The Chicken or the Egg?. Biological psychiatry. 2022 Comment GET IT
Neurocognitive impact of Zika virus infection in adult rhesus macaques. Journal of neuroinflammation. 2022 Academic Article GET IT
Times cited: 3
Monitoring Circulating Immune Checkpoint Proteins as Predictors of Non-AIDS Morbid Events in People With HIV Initiating Antiretroviral Therapy. Open forum infectious diseases. 2022 Academic Article GET IT
Times cited: 1
Emerging Single-cell Approaches to Understand HIV in the Central Nervous System. Current HIV/AIDS reports. 2021 Review GET IT
Times cited: 3
Candidate host epigenetic marks predictive for HIV reservoir size, responsiveness to latency reversal, and viral rebound. AIDS (London, England). 2021 Academic Article GET IT
Times cited: 3
Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ART. PLoS pathogens. 2021 Academic Article GET IT
Times cited: 6
Caspases and therapeutic potential of caspase inhibitors in moderate-severe SARS-CoV-2 infection and long COVID. Allergy. 2021 Academic Article GET IT
Times cited: 22
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19. Journal of leukocyte biology. 2021 Academic Article GET IT
Times cited: 55
CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2020 Academic Article GET IT
Times cited: 67
Effects of Brief Adjunctive Metformin Therapy in Virologically Suppressed HIV-Infected Adults on Polyfunctional HIV-Specific CD8 T Cell Responses to PD-L1 Blockade. AIDS research and human retroviruses. 2020 Academic Article GET IT
Times cited: 4
Intestinal Inflammation Modulates the Expression of ACE2 and TMPRSS2 and Potentially Overlaps With the Pathogenesis of SARS-CoV-2-related Disease. Gastroenterology. 2020 Academic Article GET IT
Times cited: 74
Changes in gastrointestinal microbial communities influence HIV-specific CD8+ T-cell responsiveness to immune checkpoint blockade. AIDS (London, England). 2020 Academic Article GET IT
Times cited: 3
Genome-wide epigenetic analyses in Japanese immigrant plantation workers with Parkinson's disease and exposure to organochlorines reveal possible involvement of glial genes and pathways involved in neurotoxicity. BMC neuroscience. 2020 Academic Article GET IT
Times cited: 11
Associations Between Plasma Immunomodulatory and Inflammatory Mediators With VACS Index Scores Among Older HIV-Infected Adults on Antiretroviral Therapy. Frontiers in immunology. 2020 Academic Article GET IT
Times cited: 11
Disruption of the CCL5/RANTES-CCR5 Pathway Restores Immune Homeostasis and Reduces Plasma Viral Load in Critical COVID-19. medRxiv : the preprint server for health sciences. 2020 Article GET IT
Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection. Frontiers in immunology. 2019 Academic Article GET IT
Metabolic Framework for the Improvement of Autism Spectrum Disorders by a Modified Ketogenic Diet: A Pilot Study. Journal of proteome research. 2019 Academic Article GET IT
Times cited: 17
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells. American journal of physiology. Endocrinology and metabolism. 2019 Academic Article GET IT
Times cited: 10
Epigenetic Delay in the Neurodevelopmental Trajectory of DNA Methylation States in Autism Spectrum Disorders. Frontiers in genetics. 2019 Academic Article GET IT
Times cited: 116
Comparative DNA methylomic analyses reveal potential origins of novel epigenetic biomarkers of insulin resistance in monocytes from virally suppressed HIV-infected adults. Clinical epigenetics. 2019 Academic Article GET IT
Times cited: 10
Machine learning selected smoking-associated DNA methylation signatures that predict HIV prognosis and mortality. Clinical epigenetics. 2018 Academic Article GET IT
Times cited: 28
Anti-α4β7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1-infected individuals. Science translational medicine. 2018 Academic Article GET IT
Times cited: 53
Juvenile Shank3b deficient mice present with behavioral phenotype relevant to autism spectrum disorder. Behavioural brain research. 2018 Academic Article GET IT
Times cited: 16
A modified ketogenic gluten-free diet with MCT improves behavior in children with autism spectrum disorder. Physiology & behavior. 2018 Academic Article GET IT
Times cited: 60
HTLV-1 Infection and Neuropathogenesis in the Context of Rag1^-/-γc^-/- (RAG1-Hu) and BLT Mice. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2017 Academic Article GET IT
Times cited: 13
Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment. Scientific reports. 2016 Academic Article GET IT
Times cited: 29
A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure. Disease models & mechanisms. 2016 Academic Article GET IT
Times cited: 12
Semiconductor-based sequencing of genome-wide DNA methylation states. Epigenetics. 2015 Academic Article GET IT
Times cited: 6
Heparan sulfate deficiency in autistic postmortem brain tissue from the subventricular zone of the lateral ventricles. Behavioural brain research. 2013 Academic Article GET IT
Times cited: 41
The BTBR T+ tf/J mouse model for autism spectrum disorders-in search of biomarkers. Behavioural brain research. 2012 Review GET IT
Times cited: 100
Reduced sulfate plasma concentrations in the BTBR T+tf/J mouse model of autism. Physiology & behavior. 2012 Academic Article GET IT
Times cited: 9
Facial expressions of mice in aggressive and fearful contexts. Physiology & behavior. 2012 Academic Article GET IT
Times cited: 58
Stress-induced enhancement of fear conditioning and sensitization facilitates extinction-resistant and habituation-resistant fear behaviors in a novel animal model of posttraumatic stress disorder. Physiology & behavior. 2011 Academic Article GET IT
Times cited: 24

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Research

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Co-investigator Network

Funding awarded

Investigating Cellular Immunometabolic Mechanisms Underlying HIV-Related Cardiovascular Disease Risk awarded by National Heart, Lung, & Blood Institute Principal Investigator 2021 - 2025
Epigenetic dysregulation of inflammation linked to longitudinal cardiac toxicity in perinatal HIV infection awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2022 - 2024
The role of epigenetic transcriptional memory in monocyte-macrophage cells and cardiovascular disease risk awarded by National Heart, Lung, & Blood Institute Principal Investigator 2020 - 2023

Integrative Single Cell isoform and chromatin accessibility Mapping of Chronic Opioid Exposure in Cognitive Brain Areas in HIV awarded by National Institute on Drug Abuse Co-Investigator 2022 - 2026
Integrative Single Cell Isoform And Chromatin Accessibility Mapping Of Chronic Opioid Exposure In Cognitive Brain Areas In HIV awarded by National Institute on Drug Abuse Co-Investigator 2021 - 2026
HOPE - HIV Obstruction by Programmed Epigenetics awarded by National Institute of Mental Health Co-Investigator 2021 - 2026
Harnessing Single Cell Epigenome-wide profiling of Myeloid cells to Compare and Contrast Alzheimer''s from HIV-Associated Cognitive Dysfunction awarded by National Institute on Aging Co-Investigator 2020 - 2025
WMD ECHO Detector awarded by National Heart, Lung, & Blood Institute Co-Investigator 2019 - 2023

Elucidating single cell changes in neurogenic brain regions during HIV and cannabinoid exposure awarded by National Institute on Drug Abuse Key Personnel 2023 - 2028

CNS Viral Persistence and Neuropsychiatric Perturbations in HIV: Single cell and Molecular Interrogation awarded by Gary and Mary West Health Institute Principal Investigator Subaward 2022 - 2026
NK cell memory development in HIV acute infection and vaccination awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2022 - 2024
Impact of Microbial Dysbiosis on MAIT Cell Tissue Repair Program after Acute HIV Infection awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2022 - 2024
Epigenetics of HIV, Aging, and Sleep Deficiency awarded by Gary and Mary West Health Institute Principal Investigator Subaward 2022 - 2023

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Background

education and training

Ph.D., University of Hawaii 2913
M.A., University of Hawaii 2011
B.S., University of California, San Diego 2008

Contact

full name

Michael Corley

primary email

mjc4002@med.cornell.edu

VIVO Weill Cornell Medical College

Michael Corley Assistant Professor of Immunology in Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email