McDevitt, Michael

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Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy. Proceedings of the National Academy of Sciences of the United States of America. 2020 Academic Article GET IT
Times cited: 7
A Genomic Profile of Local Immunity in the Melanoma Microenvironment Following Treatment with α Particle-Emitting Ultrasmall Silica Nanoparticles. Cancer biotherapy & radiopharmaceuticals. 2020 Academic Article GET IT
Times cited: 12
Harnessing Androgen Receptor Pathway Activation for Targeted Alpha Particle Radioimmunotherapy of Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 15
The effects of amine-modified single-walled carbon nanotubes on the mouse microbiota. International journal of nanomedicine. 2018 Academic Article GET IT
Times cited: 2
Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer. Nature communications. 2018 Academic Article GET IT
Times cited: 28
α-Emitters for Radiotherapy: From Basic Radiochemistry to Clinical Studies-Part 1. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Review GET IT
Times cited: 100
α-Emitters for Radiotherapy: From Basic Radiochemistry to Clinical Studies-Part 2. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Review GET IT
Times cited: 54
Targeted and Nontargeted α-Particle Therapies. Annual review of biomedical engineering. 2018 Review GET IT
Times cited: 34
Carbon nanotubes exhibit fibrillar pharmacology in primates. PloS one. 2017 Academic Article GET IT
Times cited: 12
In vivo immuno-targeting of an extracellular epitope of membrane bound preferentially expressed antigen in melanoma (PRAME). Oncotarget. 2017 Academic Article GET IT
Times cited: 17
Advances in the clinical translation of nanotechnology. Current opinion in biotechnology. 2017 Review GET IT
Times cited: 20
Deconvoluting hepatic processing of carbon nanotubes. Nature communications. 2016 Academic Article GET IT
Times cited: 43
Remodeling the Vascular Microenvironment of Glioblastoma with α-Particles. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Academic Article GET IT
Times cited: 16
Vascular Targeted Radioimmunotherapy for the Treatment of Glioblastoma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Academic Article GET IT
Times cited: 28
Targeted fibrillar nanocarbon RNAi treatment of acute kidney injury. Science translational medicine. 2016 Academic Article GET IT
Times cited: 75
Synthesis, pharmacokinetics, and biological use of lysine-modified single-walled carbon nanotubes. International journal of nanomedicine. 2014 Academic Article GET IT
Times cited: 27
Fibrillous carbon nanotube: an unexpected journey. Critical reviews in oncogenesis. 2014 Review GET IT
Times cited: 9
Self-assembly of carbon nanotubes and antibodies on tumours for targeted amplified delivery. Nature nanotechnology. 2013 Academic Article GET IT
Times cited: 89
Carbon nanotubes as vaccine scaffolds. Advanced drug delivery reviews. 2013 Review GET IT
Times cited: 55
A self-assembling short oligonucleotide duplex suitable for pretargeting. Nucleic acid therapeutics. 2013 Academic Article GET IT
Times cited: 9
Deploying RNA and DNA with Functionalized Carbon Nanotubes. The journal of physical chemistry. C, Nanomaterials and interfaces. 2013 Academic Article GET IT
Times cited: 31
Actinium-225 in targeted alpha-particle therapeutic applications. Current radiopharmaceuticals. 2011 Review GET IT
Times cited: 87
Alpha particles induce apoptosis through the sphingomyelin pathway. Radiation research. 2011 Academic Article GET IT
Times cited: 24
Selective killing of tumor neovasculature paradoxically improves chemotherapy delivery to tumors. Cancer research. 2010 Academic Article GET IT
Times cited: 60
A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia. Nucleic acids research. 2010 Academic Article GET IT
Times cited: 154
Imaging and treating tumor vasculature with targeted radiolabeled carbon nanotubes. International journal of nanomedicine. 2010 Academic Article GET IT
Times cited: 152
Sequential cytarabine and alpha-particle immunotherapy with bismuth-213-lintuzumab (HuM195) for acute myeloid leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research. 2010 Academic Article GET IT
Times cited: 205
Paradoxical glomerular filtration of carbon nanotubes. Proceedings of the National Academy of Sciences of the United States of America. 2010 Academic Article GET IT
Times cited: 310
Conscripts of the infinite armada: systemic cancer therapy using nanomaterials. Nature reviews. Clinical oncology. 2010 Review GET IT
Times cited: 178
MIRD Pamphlet No. 22 (abridged): radiobiology and dosimetry of alpha-particle emitters for targeted radionuclide therapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2010 Academic Article GET IT
Times cited: 309
Large anti-HER2/neu liposomes for potential targeted intraperitoneal therapy of micrometastatic cancer. Journal of liposome research. 2010 Academic Article GET IT
Times cited: 12
Synthesis and biodistribution of oligonucleotide-functionalized, tumor-targetable carbon nanotubes. Nano letters. 2008 Academic Article GET IT
Times cited: 73
Realizing the potential of the Actinium-225 radionuclide generator in targeted alpha particle therapy applications. Advanced drug delivery reviews. 2008 Review GET IT
Times cited: 144
Targeted nanomaterials for radiotherapy. Nanomedicine (London, England). 2007 Academic Article GET IT
Times cited: 34
Enhanced retention of the alpha-particle-emitting daughters of Actinium-225 by liposome carriers. Bioconjugate chemistry. 2007 Academic Article GET IT
Times cited: 76
PET imaging of soluble yttrium-86-labeled carbon nanotubes in mice. PloS one. 2007 Academic Article GET IT
Times cited: 166
Tumor targeting with antibody-functionalized, radiolabeled carbon nanotubes. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2007 Academic Article GET IT
Times cited: 415
Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization. Genes & development. 2007 Academic Article GET IT
Times cited: 353
Selective alpha-particle mediated depletion of tumor vasculature with vascular normalization. PloS one. 2007 Academic Article GET IT
Times cited: 5
Mitigation of radiation nephropathy after internal alpha-particle irradiation of kidneys. International journal of radiation oncology, biology, physics. 2006 Academic Article GET IT
Times cited: 78
Influence of the linker on the biodistribution and catabolism of actinium-225 self-immolative tumor-targeted isotope generators. Bioconjugate chemistry. 2006 Academic Article GET IT
Times cited: 23
Immunoreactivity assay for alpha-particle emitting monoclonal antibody constructs. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2005 Academic Article GET IT
Times cited: 7
Renal tubulointerstitial changes after internal irradiation with alpha-particle-emitting actinium daughters. Journal of the American Society of Nephrology : JASN. 2005 Academic Article GET IT
Times cited: 67
Efforts to control the errant products of a targeted in vivo generator. Cancer research. 2005 Academic Article GET IT
Times cited: 75
Treatment of neuroblastoma meningeal carcinomatosis with intrathecal application of alpha-emitting atomic nanogenerators targeting disialo-ganglioside GD2. Clinical cancer research : an official journal of the American Association for Cancer Research. 2004 Academic Article GET IT
Times cited: 41
Alpha-particle emitting atomic generator (Actinium-225)-labeled trastuzumab (herceptin) targeting of breast cancer spheroids: efficacy versus HER2/neu expression. Clinical cancer research : an official journal of the American Association for Cancer Research. 2004 Academic Article GET IT
Times cited: 80
Targeted deletion of T-cell clones using alpha-emitting suicide MHC tetramers. Blood. 2004 Academic Article GET IT
Times cited: 30
Engineered liposomes for potential alpha-particle therapy of metastatic cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2004 Academic Article GET IT
Times cited: 115
Pharmacokinetics, dosimetry, and toxicity of the targetable atomic generator, 225Ac-HuM195, in nonhuman primates. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2004 Academic Article GET IT
Times cited: 112
Targeted actinium-225 in vivo generators for therapy of ovarian cancer. Cancer research. 2003 Academic Article GET IT
Times cited: 130
Design and synthesis of 225Ac radioimmunopharmaceuticals. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2002 Academic Article GET IT
Times cited: 173
Targeted alpha particle immunotherapy for myeloid leukemia. Blood. 2002 Academic Article GET IT
Times cited: 408
Ac-225 and her daughters: the many faces of Shiva. Cell death and differentiation. 2002 Article GET IT
Times cited: 24
Radioimmunotherapy for model B cell malignancies using 90Y-labeled anti-CD19 and anti-CD20 monoclonal antibodies. Leukemia. 2002 Academic Article GET IT
Times cited: 54
Tumor therapy with targeted atomic nanogenerators. Science (New York, N.Y.). 2001 Academic Article GET IT
Times cited: 396
Breakthrough of 225Ac and its radionuclide daughters from an 225Ac/213Bi generator: development of new methods, quantitative characterization, and implications for clinical use. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2001 Academic Article GET IT
Times cited: 48
Rapid preparation of short-lived alpha particle emitting radioimmunopharmaceuticals. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2001 Academic Article GET IT
Times cited: 22
Response of LNCaP spheroids after treatment with an alpha-particle emitter (213Bi)-labeled anti-prostate-specific membrane antigen antibody (J591). Cancer research. 2001 Academic Article GET IT
Times cited: 93
An alpha-particle emitting antibody ([213Bi]J591) for radioimmunotherapy of prostate cancer. Cancer research. 2000 Academic Article GET IT
Times cited: 230
Pharmacokinetics and dosimetry of an alpha-particle emitter labeled antibody: 213Bi-HuM195 (anti-CD33) in patients with leukemia. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1999 Academic Article GET IT
Times cited: 196
Preparation of alpha-emitting 213Bi-labeled antibody constructs for clinical use. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1999 Academic Article GET IT
Times cited: 112
An 225Ac/213Bi generator system for therapeutic clinical applications: construction and operation. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 1999 Academic Article GET IT
Times cited: 95
Alpha-emitting bismuth cyclohexylbenzyl DTPA constructs of recombinant humanized anti-CD33 antibodies: pharmacokinetics, bioactivity, toxicity and chemistry. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1999 Academic Article GET IT
Times cited: 178
Radioimmunotherapy with alpha-emitting nuclides. European journal of nuclear medicine. 1998 Review GET IT
Times cited: 368
Rhenium-186-labeled monoclonal antibodies for radioimmunotherapy: preparation and evaluation. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1993 Academic Article GET IT
Times cited: 65
Evaluation of biological response modifiers in the enhancement of tumor uptake of technetium-99m labeled macromolecules. A preliminary report. Journal of immunological methods. 1992 Academic Article GET IT
Times cited: 19

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Background

education and training

M.E., City College, City University of New York 2004
Ph.D., Case Western Reserve University 1985
B.A., Case Western Reserve University 1980

Contact

full name

Michael McDevitt

VIVO Weill Cornell Medical College

Michael McDevitt Professor of Radiochemistry and Radiopharmancy in Radiology

Publications

selected publications

Background

education and training

Contact

full name