Nishimura, Nozomi

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selected publications

In Vivo Femtosecond Laser Subsurface Cortical Microtransections Attenuate Acute Rat Focal Seizures. Cerebral cortex (New York, N.Y. : 1991). 2019 Academic Article GET IT
Times cited: 3
Preventing dementia by preventing stroke: The Berlin Manifesto. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2019 Review GET IT
Times cited: 159
Endothelial cells promote 3D invasion of GBM by IL-8-dependent induction of cancer stem cell properties. Scientific reports. 2019 Academic Article GET IT
Times cited: 55
Deep convolutional neural networks for segmenting 3D in vivo multiphoton images of vasculature in Alzheimer disease mouse models. PloS one. 2019 Academic Article GET IT
Times cited: 33
Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models. Nature neuroscience. 2019 Academic Article GET IT
Times cited: 208
Aspirin treatment does not increase microhemorrhage size in young or aged mice. PloS one. 2019 Academic Article GET IT
Times cited: 2
In Vivo Calcium Imaging of Cardiomyocytes in the Beating Mouse Heart With Multiphoton Microscopy. Frontiers in physiology. 2018 Academic Article GET IT
Times cited: 1552
Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging. Scientific reports. 2018 Academic Article GET IT
Times cited: 18
Diverse Inflammatory Response After Cerebral Microbleeds Includes Coordinated Microglial Migration and Proliferation. Stroke. 2018 Academic Article GET IT
Times cited: 42
Label-free imaging of atherosclerotic plaques using third-harmonic generation microscopy. Biomedical optics express. 2017 Academic Article GET IT
Times cited: 65
Experimentally constrained circuit model of cortical arteriole networks for understanding flow redistribution due to occlusion and neural activation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2017 Academic Article GET IT
Times cited: 6
Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations. Nature communications. 2017 Academic Article GET IT
Times cited: 68
A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self-renewal. Molecular systems biology. 2017 Academic Article GET IT
Times cited: 33
In vivo three-photon imaging of activity of GCaMP6-labeled neurons deep in intact mouse brain. Nature methods. 2017 Academic Article GET IT
Times cited: 330
A circuit motif in the zebrafish hindbrain for a two alternative behavioral choice to turn left or right. eLife. 2016 Academic Article GET IT
Times cited: 38
Simultaneous optical and electrical in vivo analysis of the enteric nervous system. Nature communications. 2016 Academic Article GET IT
Times cited: 41
Use of Tethered Enzymes as a Platform Technology for Rapid Analyte Detection. PloS one. 2015 Academic Article GET IT
Times cited: 7
A mathematical model relating cortical oxygenated and deoxygenated hemoglobin flows and volumes to neural activity. Journal of neural engineering. 2015 Academic Article GET IT
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting. Nature biotechnology. 2015 Academic Article GET IT
Times cited: 25
Robust and fragile aspects of cortical blood flow in relation to the underlying angioarchitecture. Microcirculation (New York, N.Y. : 1994). 2015 Review GET IT
Times cited: 63
Mechanistic insight into the TH1-biased immune response to recombinant subunit vaccines delivered by probiotic bacteria-derived outer membrane vesicles. PloS one. 2014 Academic Article GET IT
Times cited: 35
Growth and hemodynamics after early embryonic aortic arch occlusion. Biomechanics and modeling in mechanobiology. 2014 Academic Article GET IT
Times cited: 26
Stalled cerebral capillary blood flow in mouse models of essential thrombocythemia and polycythemia vera revealed by in vivo two-photon imaging. Journal of thrombosis and haemostasis : JTH. 2014 Academic Article GET IT
Times cited: 31
Optically induced occlusion of single blood vessels in rodent neocortex. Cold Spring Harbor protocols. 2013 Academic Article GET IT
Times cited: 10
Optoporation and genetic manipulation of cells using femtosecond laser pulses. Biophysical journal. 2013 Academic Article GET IT
Times cited: 50
Big effects from tiny vessels: imaging the impact of microvascular clots and hemorrhages on the brain. Stroke. 2013 Review GET IT
Times cited: 15
Stimulus-evoked calcium transients in somatosensory cortex are temporarily inhibited by a nearby microhemorrhage. PloS one. 2013 Academic Article GET IT
Times cited: 30
Three-photon excited fluorescence imaging of unstained tissue using a GRIN lens endoscope. Biomedical optics express. 2013 Academic Article GET IT
Times cited: 139
Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2012 Review GET IT
Times cited: 324
In vivo two-photon excited fluorescence microscopy reveals cardiac- and respiration-dependent pulsatile blood flow in cortical blood vessels in mice. American journal of physiology. Heart and circulatory physiology. 2012 Academic Article GET IT
Times cited: 101
Age-related intimal stiffening enhances endothelial permeability and leukocyte transmigration. Science translational medicine. 2011 Academic Article GET IT
Times cited: 275
Cortical microhemorrhages cause local inflammation but do not trigger widespread dendrite degeneration. PloS one. 2011 Academic Article GET IT
Times cited: 66
Real-time imaging of perivascular transport of nanoparticles during convection-enhanced delivery in the rat cortex. Annals of biomedical engineering. 2011 Academic Article GET IT
Times cited: 38
Preictal and ictal neurovascular and metabolic coupling surrounding a seizure focus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 Academic Article GET IT
Times cited: 91
Sub-surface, micrometer-scale incisions produced in rodent cortex using tightly-focused femtosecond laser pulses. Lasers in surgery and medicine. 2011 Academic Article GET IT
Times cited: 14
Occlusion of cortical ascending venules causes blood flow decreases, reversals in flow direction, and vessel dilation in upstream capillaries. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2011 Academic Article GET IT
Times cited: 64
Limitations of collateral flow after occlusion of a single cortical penetrating arteriole. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2010 Academic Article GET IT
Times cited: 85
Two-photon microscopy-guided femtosecond-laser photoablation of avian cardiogenesis: noninvasive creation of localized heart defects. American journal of physiology. Heart and circulatory physiology. 2010 Academic Article GET IT
Times cited: 29
Deep tissue multiphoton microscopy using longer wavelength excitation. Optics express. 2009 Academic Article GET IT
Times cited: 482
Flexible microfluidic devices supported by biodegradable insertion scaffolds for convection-enhanced neural drug delivery. Biomedical microdevices. 2009 Academic Article GET IT
Times cited: 50
Suppressed neuronal activity and concurrent arteriolar vasoconstriction may explain negative blood oxygenation level-dependent signal. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2007 Academic Article GET IT
Times cited: 302
Penetrating arterioles are a bottleneck in the perfusion of neocortex. Proceedings of the National Academy of Sciences of the United States of America. 2006 Academic Article GET IT
Times cited: 263
Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke. Nature methods. 2006 Academic Article GET IT
Times cited: 256
Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion. PLoS biology. 2006 Academic Article GET IT
Times cited: 286
Dynamics of femtosecond laser-induced breakdown in water from femtoseconds to microseconds. Optics express. 2002 Academic Article GET IT
Times cited: 243
Minimally disruptive laser-induced breakdown in water. Optics letters. 1997 Academic Article GET IT
Times cited: 72

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Background

education and training

Ph.D., University of California, San Diego 2006
B.A., Harvard College 1999

Contact

full name

Nozomi Nishimura

VIVO Weill Cornell Medical College

Nozomi Nishimura Assistant Professor of Neuroscience

Publications

selected publications

Background

education and training

Contact

full name