selected publications
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Pegylated interferon alfa-2a for polycythemia vera or essential thrombocythemia resistant or intolerant to hydroxyurea.
Blood.
2019
Academic Article
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Times cited: 97 -
Emerging translational science discoveries, clonal approaches, and treatment trends in chronic myeloproliferative neoplasms.
Hematological oncology.
2019
Review
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Times cited: 7 -
Efficacy of MEK inhibition in patients with histiocytic neoplasms.
Nature.
2019
Academic Article
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Times cited: 165 -
Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis.
Blood.
2018
Academic Article
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Times cited: 29 -
Single-agent dabrafenib for BRAFV600E-mutated histiocytosis.
Haematologica.
2018
Academic Article
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Times cited: 32 -
Phase 2 trial of a multivalent WT1 peptide vaccine (galinpepimut-S) in acute myeloid leukemia.
Blood advances.
2018
Academic Article
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Times cited: 91 -
JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.
The Journal of clinical investigation.
2018
Academic Article
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Times cited: 56 -
Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.
Cancer cell.
2017
Academic Article
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Times cited: 137 -
Myeloid Growth Factors, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.
Journal of the National Comprehensive Cancer Network : JNCCN.
2017
Academic Article
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Times cited: 93 -
Hsp90 inhibition disrupts JAK-STAT signaling and leads to reductions in splenomegaly in patients with myeloproliferative neoplasms.
Haematologica.
2017
Letter
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Times cited: 15 -
NCCN Guidelines Insights: Myeloproliferative Neoplasms, Version 2.2018.
2017
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Times cited: 95 -
High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis.
Blood.
2017
Academic Article
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Times cited: 86 -
Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells.
Blood.
2017
Academic Article
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Times cited: 75 -
Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia.
Cell stem cell.
2017
Academic Article
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Times cited: 92 -
Myeloproliferative Neoplasms, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.
2016
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Times cited: 52 -
The use of Erwinia asparaginase for adult patients with acute lymphoblastic leukemia after pegaspargase intolerance.
Leukemia research.
2016
Academic Article
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Times cited: 16 -
Diffuse reduction of cerebral grey matter volumes in Erdheim-Chester disease.
Orphanet journal of rare diseases.
2016
Letter
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Times cited: 19 -
Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis.
The Journal of experimental medicine.
2016
Academic Article
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Times cited: 104 -
Telomere length and associations with somatic mutations and clinical outcomes in acute myeloid leukemia.
Leukemia research.
2016
Academic Article
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Times cited: 13 -
Mutational correlates of response to hypomethylating agent therapy in acute myeloid leukemia.
Haematologica.
2016
Letter
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Times cited: 27 -
Bisphosphonates in Langerhans Cell Histiocytosis: An International Retrospective Case Series.
Mediterranean journal of hematology and infectious diseases.
2016
Academic Article
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Times cited: 54 -
Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemia.
Haematologica.
2016
Review
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Times cited: 62 -
Contemporary insights into the pathogenesis and treatment of chronic myeloproliferative neoplasms.
Leukemia & lymphoma.
2016
Review
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Times cited: 5 -
Clinical response to ruxolitinib in CSF3R T618-mutated chronic neutrophilic leukemia.
Annals of hematology.
2016
Letter
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Times cited: 26 -
Genetic analysis of five children with essential thrombocytosis identified mutations in cancer-associated genes with roles in transcriptional regulation.
Haematologica.
2016
Letter
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Times cited: 13 -
Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting.
Blood.
2016
Academic Article
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Times cited: 208 -
Polycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery of JAK2 V617F.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2015
Review
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Times cited: 49 -
Fibrogenesis in Primary Myelofibrosis: Diagnostic, Clinical, and Therapeutic Implications.
The oncologist.
2015
Review
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Times cited: 12 -
An international data set for CMML validates prognostic scoring systems and demonstrates a need for novel prognostication strategies.
Blood cancer journal.
2015
Academic Article
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Times cited: 97 -
CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms.
Cancer cell.
2015
Academic Article
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Times cited: 110 -
Clinical and molecular genetic characterization of myelofibrosis.
Current opinion in hematology.
2015
Review
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Times cited: 15 -
JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response.
Cancer discovery.
2015
Academic Article
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Times cited: 212 -
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Cell reports.
2014
Academic Article
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Times cited: 206 -
Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms.
Proceedings of the National Academy of Sciences of the United States of America.
2014
Academic Article
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Times cited: 209 -
Novel insights into the biology and treatment of chronic myeloproliferative neoplasms.
Leukemia & lymphoma.
2014
Review
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Times cited: 3 -
Prospective blinded study of BRAFV600E mutation detection in cell-free DNA of patients with systemic histiocytic disorders.
Cancer discovery.
2014
Academic Article
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Times cited: 105 -
JAK2 inhibitors do not affect stem cells present in the spleens of patients with myelofibrosis.
Blood.
2014
Academic Article
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Times cited: 28 -
Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease.
Blood.
2014
Academic Article
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Times cited: 176 -
Integrating genomics into prognostic models for AML.
Seminars in hematology.
2014
Academic Article
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Times cited: 6 -
A primer on genomic and epigenomic alterations in the myeloproliferative neoplasms.
Best practice & research. Clinical haematology.
2014
Review
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Times cited: 17 -
Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia.
Science translational medicine.
2014
Academic Article
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Times cited: 98 -
Development of extramedullary sites of leukaemia during ruxolitinib therapy for myelofibrosis.
British journal of haematology.
2014
Letter
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Times cited: 23 -
Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis.
Blood.
2014
Academic Article
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Times cited: 310 -
Efficacy of intermittent combined RAF and MEK inhibition in a patient with concurrent BRAF- and NRAS-mutant malignancies.
2014
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Times cited: 67 -
Pathogenesis and management of acute myeloid leukemia that has evolved from a myeloproliferative neoplasm.
Current opinion in hematology.
2014
Review
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Times cited: 29 -
Acute myeloid leukemia presenting with panhypopituitarism or diabetes insipidus: a case series with molecular genetic analysis and review of the literature.
Leukemia & lymphoma.
2014
Review
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Times cited: 16 -
Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms.
Blood.
2014
Academic Article
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Times cited: 89 -
Leveraging cancer genome information in hematologic malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2013
Review
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Times cited: 12 -
Progression of RAS-mutant leukemia during RAF inhibitor treatment.
2012
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Times cited: 197 -
Translocation t(11;17) in de novo myelodysplastic syndrome not associated with acute myeloid or acute promyelocytic leukemia.
2012
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Times cited: 3 -
Proposed criteria for response assessment in patients treated in clinical trials for myeloproliferative neoplasms in blast phase (MPN-BP): formal recommendations from the post-myeloproliferative neoplasm acute myeloid leukemia consortium.
2012
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Times cited: 43 -
Genetic analysis of patients with leukemic transformation of myeloproliferative neoplasms shows recurrent SRSF2 mutations that are associated with adverse outcome.
Blood.
2012
Academic Article
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Times cited: 179 -
Finding a needle in a haystack: whole genome sequencing and mutation discovery in murine models.
The Journal of clinical investigation.
2011
Comment
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Times cited: 3