selected publications
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High apoptotic endothelial microparticle levels measured in asthma with elevated IgE and eosinophils.
Respiratory research.
2023
Letter
GET IT
Times cited: 42 - Integrative multi-omics analysis reveals novel idiopathic pulmonary fibrosis endotypes associated with disease progression. Respiratory research. 2023 Academic Article GET IT
- A blood and bronchoalveolar lavage protein signature of rapid FEV1 decline in smoking-associated COPD. Scientific reports. 2023 Academic Article GET IT
- Changes in Lung Volumes with Spirometric Disease Progression in COPD. Chronic obstructive pulmonary diseases (Miami, Fla.). 2023 Academic Article GET IT
- Validity and Reliability of the Fatigue Severity Scale in a Real-World Interstitial Lung Disease Cohort. American journal of respiratory and critical care medicine. 2023 Academic Article GET IT
- Reduced quantity and function of pneumococcal antibodies are associated with exacerbations of COPD in SPIROMICS. Clinical immunology (Orlando, Fla.). 2023 Academic Article GET IT
- Use of the Iron Chelator Deferiprone to Restore Function in BAL Fluid Macrophages in Smoking and Chronic Obstructive Pulmonary Disease. American journal of respiratory cell and molecular biology. 2023 Letter GET IT
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Diagnosis and Pharmacologic Management of Fibrotic Interstitial Lung Disease.
Life (Basel, Switzerland).
2023
Review
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Times cited: 164 -
Expert consensus on the management of systemic sclerosis-associated interstitial lung disease.
Respiratory research.
2023
Academic Article
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Times cited: 3 -
Patients with allergic asthma have lower risk of severe COVID-19 outcomes than patients with nonallergic asthma.
BMC pulmonary medicine.
2022
Academic Article
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Times cited: 1 -
Clinical Implications of Low Absolute Blood Eosinophil Count in the SPIROMICS COPD Cohort.
Chest.
2022
Academic Article
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Times cited: 1 -
Clinical Trial of Losartan for Pulmonary Emphysema: Pulmonary Trials Cooperative Losartan Effects on Emphysema Progression Clinical Trial.
American journal of respiratory and critical care medicine.
2022
Academic Article
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Times cited: 7 -
Bronchodilators in Tobacco-Exposed Persons with Symptoms and Preserved Lung Function.
The New England journal of medicine.
2022
Academic Article
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Times cited: 18 -
Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease.
American journal of respiratory and critical care medicine.
2022
Academic Article
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Times cited: 9 - Premature Aging of the Airway Epithelium in Chronic Obstructive Pulmonary Disease in People Living with HIV. American journal of respiratory and critical care medicine. 2022 Editorial Article GET IT
- Choices and Outcomes of the Oldest Old Admitted During the First Wave of COVID-19 in New York City. Journal of palliative care. 2022 Academic Article GET IT
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Misalignment between Clinical Mold Antigen Extracts and Airborne Molds Found in Water-damaged Homes.
Annals of the American Thoracic Society.
2022
Academic Article
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Times cited: 3 -
Impaired differentiation of small airway basal stem/progenitor cells in people living with HIV.
Scientific reports.
2022
Academic Article
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Times cited: 2 - Smoking shifts human small airway epithelium club cells toward a lesser differentiated population. NPJ genomic medicine. 2021 Academic Article GET IT
- Up-regulation of ACE2, the SARS-CoV-2 receptor, in asthmatics on maintenance inhaled corticosteroids. Respiratory research. 2021 Academic Article GET IT
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The spectrum of progressive fibrosis interstitial lung disease: clinical and managed care considerations.
The American journal of managed care.
2021
Academic Article
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Times cited: 1 -
Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium.
Genome medicine.
2021
Academic Article
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Times cited: 15 -
HIV induces airway basal progenitor cells to adopt an inflammatory phenotype.
Scientific reports.
2021
Academic Article
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Times cited: 7 -
Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort.
NPJ biofilms and microbiomes.
2021
Academic Article
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Times cited: 22 -
Ratio of FEV1/Slow Vital Capacity of < 0.7 Is Associated With Clinical, Functional, and Radiologic Features of Obstructive Lung Disease in Smokers With Preserved Lung Function.
Chest.
2021
Academic Article
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Times cited: 5 -
Establishing content-validity of a disease-specific health-related quality of life instrument for patients with chronic hypersensitivity pneumonitis.
Journal of patient-reported outcomes.
2021
Academic Article
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Times cited: 111 -
Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2.
Science translational medicine.
2020
Academic Article
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Times cited: 27 -
Current smoking with or without chronic bronchitis is independently associated with goblet cell hyperplasia in healthy smokers and COPD subjects.
Scientific reports.
2020
Academic Article
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Times cited: 6 -
Dysregulation of club cell biology in idiopathic pulmonary fibrosis.
PloS one.
2020
Academic Article
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Times cited: 16 -
Cell-specific expression of lung disease risk-related genes in the human small airway epithelium.
Respiratory research.
2020
Academic Article
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Times cited: 16 -
Expert consensus on the management of adverse events and prescribing practices associated with the treatment of patients taking pirfenidone for idiopathic pulmonary fibrosis: a Delphi consensus study.
BMC pulmonary medicine.
2020
Academic Article
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Times cited: 2 -
Increased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS.
Scientific reports.
2020
Academic Article
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Times cited: 10 -
Associations between Patient-reported Outcomes and Death or Lung Transplant in Idiopathic Pulmonary Fibrosis. Data from the Idiopathic Pulmonary Fibrosis Prospective Outcomes Registry.
Annals of the American Thoracic Society.
2020
Academic Article
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Times cited: 15 -
Diagnostic and Prognostic Biomarkers for Chronic Fibrosing Interstitial Lung Diseases With a Progressive Phenotype.
Chest.
2020
Review
GET IT
Times cited: 51 -
Alveolar Macrophage Immunometabolism and Lung Function Impairment in Smoking and Chronic Obstructive Pulmonary Disease.
American journal of respiratory and critical care medicine.
2020
Letter
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Times cited: 30 -
Association of Long-term Ambient Ozone Exposure With Respiratory Morbidity in Smokers.
JAMA internal medicine.
2020
Academic Article
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Times cited: 44 -
Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis.
International journal of chronic obstructive pulmonary disease.
2019
Academic Article
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Times cited: 8 -
Radiographic lung volumes predict progression to COPD in smokers with preserved spirometry in SPIROMICS.
The European respiratory journal.
2019
Academic Article
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Times cited: 20 -
Metoprolol for the Prevention of Acute Exacerbations of COPD.
The New England journal of medicine.
2019
Academic Article
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Times cited: 84 -
Risk factors for disease progression in idiopathic pulmonary fibrosis.
Thorax.
2019
Academic Article
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Times cited: 17 -
Role of KRAS in regulating normal human airway basal cell differentiation.
Respiratory research.
2019
Academic Article
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Times cited: 2 -
Design of Idiopathic Pulmonary Fibrosis Clinical Trials in the Era of Approved Therapies.
American journal of respiratory and critical care medicine.
2019
Academic Article
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Times cited: 6 -
Predictors of death or lung transplant after a diagnosis of idiopathic pulmonary fibrosis: insights from the IPF-PRO Registry.
Respiratory research.
2019
Academic Article
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Times cited: 33 -
Exaggerated BMP4 signalling alters human airway basal progenitor cell differentiation to cigarette smoking-related phenotypes.
The European respiratory journal.
2019
Academic Article
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Times cited: 22 -
Safety and Tolerability of Comprehensive Research Bronchoscopy in Chronic Obstructive Pulmonary Disease. Results from the SPIROMICS Bronchoscopy Substudy.
Annals of the American Thoracic Society.
2019
Academic Article
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Times cited: 11 -
Alignment of Inhaled Chronic Obstructive Pulmonary Disease Therapies with Published Strategies. Analysis of the Global Initiative for Chronic Obstructive Lung Disease Recommendations in SPIROMICS.
Annals of the American Thoracic Society.
2019
Academic Article
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Times cited: 25 -
Ambient Pollution-related Reprogramming of the Human Small Airway Epithelial Transcriptome.
American journal of respiratory and critical care medicine.
2018
Academic Article
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Times cited: 13 -
Ontogeny and Biology of Human Small Airway Epithelial Club Cells.
American journal of respiratory and critical care medicine.
2018
Academic Article
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Times cited: 60 -
An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup.
The Journal of clinical investigation.
2018
Academic Article
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Times cited: 56 -
Elevated circulating MMP-9 is linked to increased COPD exacerbation risk in SPIROMICS and COPDGene.
JCI insight.
2018
Academic Article
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Times cited: 27 -
Bronchodilator responsiveness or reversibility in asthma and COPD - a need for clarity.
International journal of chronic obstructive pulmonary disease.
2018
Editorial Article
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Times cited: 10 -
Chronic Comorbid Illnesses Predict the Clinical Course of 866 Patients Requiring Prolonged Mechanical Ventilation in a Long-Term, Acute-Care Hospital.
Journal of intensive care medicine.
2018
Academic Article
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Times cited: 5 -
Genome-wide association study of lung function and clinical implication in heavy smokers.
BMC medical genetics.
2018
Academic Article
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Times cited: 22 -
Rural Residence and Chronic Obstructive Pulmonary Disease Exacerbations. Analysis of the SPIROMICS Cohort.
Annals of the American Thoracic Society.
2018
Academic Article
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Times cited: 26 -
NT-proBNP in stable COPD and future exacerbation risk: Analysis of the SPIROMICS cohort.
Respiratory medicine.
2018
Academic Article
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Times cited: 11 -
Altered lung biology of healthy never smokers following acute inhalation of E-cigarettes.
Respiratory research.
2018
Academic Article
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Times cited: 82 -
Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS.
PloS one.
2018
Academic Article
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Times cited: 22 - Seeing Deeply into the Lung in Interstitial Lung Disease. American journal of respiratory and critical care medicine. 2018 Editorial Article GET IT
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Variability in objective and subjective measures affects baseline values in studies of patients with COPD.
PloS one.
2017
Academic Article
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Times cited: 16 -
Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort.
The Journal of allergy and clinical immunology.
2017
Letter
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Times cited: 6 -
Airway Mucin Concentration as a Marker of Chronic Bronchitis.
The New England journal of medicine.
2017
Academic Article
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Times cited: 215 -
Smoking-Dependent Distal-to-Proximal Repatterning of the Adult Human Small Airway Epithelium.
American journal of respiratory and critical care medicine.
2017
Academic Article
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Times cited: 52 -
Role of OSGIN1 in mediating smoking-induced autophagy in the human airway epithelium.
Autophagy.
2017
Academic Article
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Times cited: 38 -
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue-Destructive Phenotype.
Cell reports.
2017
Academic Article
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Times cited: 10 -
AJRCCM: 100-Year Anniversary. Progress in Interstitial Lung Disease.
American journal of respiratory and critical care medicine.
2017
Academic Article
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Times cited: 3 -
Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort.
Annals of the American Thoracic Society.
2017
Academic Article
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Times cited: 27 -
Waterpipe smoking induces epigenetic changes in the small airway epithelium.
PloS one.
2017
Academic Article
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Times cited: 26 -
Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts.
American journal of respiratory and critical care medicine.
2017
Academic Article
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Times cited: 84 -
A Woman with Asthma and Ground-Glass Opacities.
Annals of the American Thoracic Society.
2017
Conference Paper
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Times cited: 3 -
Effects of Reinstitution of Prolonged Mechanical Ventilation on the Outcomes of 370 Patients in a Long-Term Acute Care Hospital.
Journal of intensive care medicine.
2016
Academic Article
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Times cited: 5 -
Efficacy of simtuzumab versus placebo in patients with idiopathic pulmonary fibrosis: a randomised, double-blind, controlled, phase 2 trial.
The Lancet. Respiratory medicine.
2016
Academic Article
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Times cited: 156 -
A Randomized Trial of Long-Term Oxygen for COPD with Moderate Desaturation.
The New England journal of medicine.
2016
Academic Article
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Times cited: 267 -
Pulmonary Abnormalities in Young, Light-Use Waterpipe (Hookah) Smokers.
American journal of respiratory and critical care medicine.
2016
Academic Article
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Times cited: 21 -
JAG1-Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium.
Stem cell reviews and reports.
2016
Academic Article
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Times cited: 17 -
Persistence of circulating endothelial microparticles in COPD despite smoking cessation.
Thorax.
2016
Academic Article
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Times cited: 37 -
The Role of Interleukin-23 in the Early Development of Emphysema in HIV1(+) Smokers.
Journal of immunology research.
2016
Academic Article
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Times cited: 8 -
Progression to COPD in smokers with normal spirometry/low DLCO using different methods to determine normal levels.
The European respiratory journal.
2016
Letter
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Times cited: 3 -
Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function.
The New England journal of medicine.
2016
Academic Article
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Times cited: 441 -
POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes.
Journal of immunology (Baltimore, Md. : 1950).
2016
Academic Article
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Times cited: 32 -
Chronic Cough and Bilateral Pneumothoraces in a Nonsmoker.
2016
GET IT
Times cited: 2 -
Relationship of the Duration of Ventilator Support to Successful Weaning and Other Clinical Outcomes in 437 Prolonged Mechanical Ventilation Patients.
Journal of intensive care medicine.
2016
Academic Article
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Times cited: 8 -
Cigarette Smoking Induces Changes in Airway Epithelial Expression of Genes Associated with Monogenic Lung Disorders.
American journal of respiratory and critical care medicine.
2016
Letter
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Times cited: 7 -
Severe Cavitary, Fistulating Mycobacterium avium-intracellulare Complex Disease in an Immunocompetent Host.
2015
GET IT
Times cited: 3 -
Risk of COPD with obstruction in active smokers with normal spirometry and reduced diffusion capacity.
The European respiratory journal.
2015
Academic Article
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Times cited: 83 -
The Idiopathic Pulmonary Fibrosis Clinical Research Network (IPFnet): diagnostic and adjudication processes.
Chest.
2015
Academic Article
GET IT
Times cited: 29 -
Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation.
PloS one.
2015
Academic Article
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Times cited: 56 -
Screening for Chronic Obstructive Pulmonary Disease (COPD) in an Urban HIV Clinic: A Pilot Study.
AIDS patient care and STDs.
2015
Academic Article
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Times cited: 15 -
Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS).
Journal of translational medicine.
2015
Academic Article
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Times cited: 33 -
Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine.
2014
Letter
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Times cited: 70 -
Smoking accelerates aging of the small airway epithelium.
Respiratory research.
2014
Academic Article
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Times cited: 57 -
Intraflagellar transport gene expression associated with short cilia in smoking and COPD.
PloS one.
2014
Academic Article
GET IT
Times cited: 58 -
Prolonged mechanical ventilation in 540 seriously ill older adults: effects of increasing age on clinical outcomes and survival.
Journal of the American Geriatrics Society.
2014
Academic Article
GET IT
Times cited: 40 -
Effects of smoking on non-AIDS-related morbidity in HIV-infected patients.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2013
Review
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Times cited: 60 -
Mast cells: a pivotal role in pulmonary fibrosis.
DNA and cell biology.
2013
Academic Article
GET IT
Times cited: 68 -
A comparison of seriously ill patients with or without AIDS requiring prolonged mechanical ventilation.
Journal of critical care.
2012
Academic Article
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Times cited: 4 -
A placebo-controlled randomized trial of warfarin in idiopathic pulmonary fibrosis.
American journal of respiratory and critical care medicine.
2012
Academic Article
GET IT
Times cited: 388 -
Beyond single-marker analyses: mining whole genome scans for insights into treatment responses in severe sepsis.
The pharmacogenomics journal.
2012
Academic Article
GET IT
Times cited: 38 -
The IPFnet Strategy: Creating a comprehensive approach in the treatment of idiopathic pulmonary fibrosis.
American journal of respiratory and critical care medicine.
2010
Editorial Article
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Times cited: 16 -
Adenovirus vectors block human immunodeficiency virus-1 replication in human alveolar macrophages by inhibition of the long terminal repeat.
American journal of respiratory cell and molecular biology.
2009
Academic Article
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Times cited: 4 -
Up-regulation of alveolar macrophage matrix metalloproteinases in HIV1(+) smokers with early emphysema.
Journal of leukocyte biology.
2009
Academic Article
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Times cited: 39 -
Acute exacerbations of idiopathic pulmonary fibrosis.
American journal of respiratory and critical care medicine.
2007
Review
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Times cited: 949 -
Alteration of splicing signals in a genomic/cDNA hybrid VEGF gene to modify the ratio of expressed VEGF isoforms enhances safety of angiogenic gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy.
2005
Academic Article
GET IT
Times cited: 25 -
VEGF levels in the alveolar compartment do not distinguish between ARDS and hydrostatic pulmonary oedema.
The European respiratory journal.
2005
Academic Article
GET IT
Times cited: 47 -
Hypoxia upregulates VEGF expression in alveolar epithelial cells in vitro and in vivo.
American journal of physiology. Lung cellular and molecular physiology.
2002
Academic Article
GET IT
Times cited: 98 -
Inhibition of HIV-1 replication in alveolar macrophages by adenovirus gene transfer vectors.
American journal of respiratory cell and molecular biology.
2002
Academic Article
GET IT
Times cited: 2 -
Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions.
Human gene therapy.
2002
Academic Article
GET IT
Times cited: 72 -
Compartmentalization of vascular endothelial growth factor to the epithelial surface of the human lung.
Molecular medicine (Cambridge, Mass.).
2001
Academic Article
GET IT
Times cited: 105 -
Linezolid (PNU-100766) versus vancomycin in the treatment of hospitalized patients with nosocomial pneumonia: a randomized, double-blind, multicenter study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2001
Academic Article
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Times cited: 442 -
Lung overexpression of the vascular endothelial growth factor gene induces pulmonary edema.
American journal of respiratory cell and molecular biology.
2000
Academic Article
GET IT
Times cited: 229 -
Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus.
The Journal of clinical investigation.
1999
Academic Article
GET IT
Times cited: 204 -
Expression and use of human immunodeficiency virus type 1 coreceptors by human alveolar macrophages.
Journal of virology.
1999
Academic Article
GET IT
Times cited: 50 -
Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor.
American journal of respiratory cell and molecular biology.
1999
Academic Article
GET IT
Times cited: 71 -
Selective expansion of alveolar macrophages in vivo by adenovirus-mediated transfer of the murine granulocyte-macrophage colony-stimulating factor cDNA.
Blood.
1999
Academic Article
GET IT
Times cited: 38 -
Pneumocystis pneumonia in the intensive care unit: location, location, location?.
Critical care medicine.
1998
Editorial Article
GET IT
Times cited: 1 -
Pulmonary complications in cancer patients.
CA: a cancer journal for clinicians.
1996
Review
GET IT
Times cited: 37 -
Altered cholesterol trafficking in herpesvirus-infected arterial cells. Evidence for viral protein kinase-mediated cholesterol accumulation.
The Journal of biological chemistry.
1995
Academic Article
GET IT
Times cited: 24 -
Aspiration emergencies.
Clinics in chest medicine.
1994
Review
GET IT
Times cited: 21 -
Developmentally regulated herpesvirus plaque formation in arterial smooth muscle cells.
Circulation research.
1993
Academic Article
GET IT
Times cited: 7 -
Fibroblast growth factor receptor: does it have a role in the binding of herpes simplex virus?.
Science (New York, N.Y.).
1991
Letter
GET IT
Times cited: 16 - Response. Science (New York, N.Y.). 1991 Academic Article GET IT
- Mechanism of herpesviral entry into cells. Role of fibroblast growth factor receptor. Annals of the New York Academy of Sciences. 1991 Academic Article GET IT
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Mediation of virion penetration into vascular cells by association of basic fibroblast growth factor with herpes simplex virus type 1.
Nature.
1990
Academic Article
GET IT
Times cited: 32 -
Fibroblast growth factor receptor is a portal of cellular entry for herpes simplex virus type 1.
Science (New York, N.Y.).
1990
Academic Article
GET IT
Times cited: 92 -
Inhibition of proteoglycan synthesis in human endothelial cells after infection with herpes simplex virus type 1 in vitro.
American journal of respiratory cell and molecular biology.
1990
Academic Article
GET IT
Times cited: 22 -
Prognostic implications of bronchoalveolar lavage neutrophilia in patients with Pneumocystis carinii pneumonia and AIDS.
The American review of respiratory disease.
1989
Editorial Article
GET IT
Times cited: 5 -
In vitro delayed hypersensitivity granuloma formation: development of an antigen-coated bead model.
Journal of immunology (Baltimore, Md. : 1950).
1985
Academic Article
GET IT
Times cited: 30