selected publications
- Activation of Sting in Response to Partial-Tumor Radiation Exposure. International journal of radiation oncology, biology, physics. 2023 Academic Article GET IT
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T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants.
Cell.
2023
Academic Article
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Times cited: 3 - Mathematical modeling suggests cytotoxic T lymphocytes control growth of B16 tumor cells in collagin-fibrin gels by cytolytic and non-lytic mechanisms. bioRxiv : the preprint server for biology. 2023 Article GET IT
- Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade. The Journal of clinical investigation. 2022 Academic Article GET IT
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Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions.
The Journal of experimental medicine.
2022
Academic Article
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Times cited: 3 -
Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of cancer.
Communications biology.
2021
Academic Article
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Times cited: 5 -
Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness.
JCI insight.
2021
Academic Article
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Times cited: 2 -
Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity.
Cancer cell.
2021
Academic Article
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Times cited: 61 -
Neoadjuvant vascular-targeted photodynamic therapy improves survival and reduces recurrence and progression in a mouse model of urothelial cancer.
Scientific reports.
2021
Academic Article
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Times cited: 2 -
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports.
2021
Academic Article
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Times cited: 14 -
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine.
Nature communications.
2020
Academic Article
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Times cited: 131 -
In vitro assays for effector T cell functions and activity of immunomodulatory antibodies.
Methods in enzymology.
2019
Academic Article
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Times cited: 3 -
In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors.
The Journal of clinical investigation.
2019
Academic Article
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Times cited: 28 -
One checkpoint may hide another: inhibiting the TGFβ signaling pathway enhances immune checkpoint blockade.
Hepatobiliary surgery and nutrition.
2019
Editorial Article
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Times cited: 378 -
Rational design of anti-GITR-based combination immunotherapy.
Nature medicine.
2019
Academic Article
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Times cited: 137 -
An Antitumor Immune Response Is Evoked by Partial-Volume Single-Dose Radiation in 2 Murine Models.
International journal of radiation oncology, biology, physics.
2018
Academic Article
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Times cited: 46 -
Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity.
Cancer cell.
2018
Academic Article
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Times cited: 11 -
Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity.
Cancer cell.
2018
Academic Article
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Times cited: 96 -
Cytokine release syndrome after radiation therapy: case report and review of the literature.
2018
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Times cited: 25 -
Systemic Antitumor Immunity by PD-1/PD-L1 Inhibition Is Potentiated by Vascular-Targeted Photodynamic Therapy of Primary Tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2017
Academic Article
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Times cited: 65 -
Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment.
Science signaling.
2017
Academic Article
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Times cited: 84 -
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses.
Cell.
2017
Academic Article
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Times cited: 54 -
Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells.
Nature.
2016
Academic Article
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Times cited: 557 -
Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells.
Cancer immunology research.
2016
Academic Article
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Times cited: 104 -
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses.
Cell.
2016
Article
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Times cited: 49 -
Clonal Abundance of Tumor-Specific CD4(+) T Cells Potentiates Efficacy and Alters Susceptibility to Exhaustion.
Immunity.
2016
Academic Article
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Times cited: 28 -
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses.
Cell.
2015
Academic Article
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Times cited: 1043 -
The New Era of Cancer Immunotherapy: Manipulating T-Cell Activity to Overcome Malignancy.
Advances in cancer research.
2015
Review
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Times cited: 40 -
MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration.
Nature communications.
2014
Academic Article
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Times cited: 213 -
Combination of alphavirus replicon particle-based vaccination with immunomodulatory antibodies: therapeutic activity in the B16 melanoma mouse model and immune correlates.
Cancer immunology research.
2014
Academic Article
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Times cited: 30 -
The importance of animal models in tumor immunity and immunotherapy.
Current opinion in genetics & development.
2013
Review
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Times cited: 56 -
GITR pathway activation abrogates tumor immune suppression through loss of regulatory T cell lineage stability.
Cancer immunology research.
2013
Academic Article
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Times cited: 119 -
Surface acoustic waves enhance neutrophil killing of bacteria.
PloS one.
2013
Academic Article
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Times cited: 5 -
Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotype.
The Journal of experimental medicine.
2012
Academic Article
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Times cited: 110 -
CD8+ T cell concentration determines their efficiency in killing cognate antigen-expressing syngeneic mammalian cells in vitro and in mouse tissues.
The Journal of experimental medicine.
2010
Academic Article
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Times cited: 93 -
Different G(i)-coupled chemoattractant receptors signal qualitatively different functions in human neutrophils.
Journal of leukocyte biology.
2002
Academic Article
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Times cited: 32 -
The bacterial peptide N-formyl-Met-Leu-Phe inhibits killing of Staphylococcus epidermidis by human neutrophils in fibrin gels.
Journal of immunology (Baltimore, Md. : 1950).
2002
Academic Article
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Times cited: 12 -
Blockade of alpha 5 beta 1 integrins reverses the inhibitory effect of tenascin on chemotaxis of human monocytes and polymorphonuclear leukocytes through three-dimensional gels of extracellular matrix proteins.
Journal of immunology (Baltimore, Md. : 1950).
2001
Academic Article
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Times cited: 49 -
Differential regulation of beta1 integrins by chemoattractants regulates neutrophil migration through fibrin.
The Journal of cell biology.
1999
Academic Article
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Times cited: 60