Reilly, Shannon

Publications

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selected publications

Obesity-dependent increase in RalA activity disrupts mitochondrial dynamics in white adipocytes. Research square. 2023 Article GET IT
Measuring the Rate of Lipolysis in Ex vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro. Journal of visualized experiments : JoVE. 2023 Academic Article GET IT
Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling. Diabetes. 2023 Academic Article GET IT
Times cited: 1
Culture and Differentiation of Primary Preadipocytes from Mouse Subcutaneous White Adipose Tissue. Methods in molecular biology (Clifton, N.J.). 2023 Academic Article GET IT
Xanthine oxidase inhibitor urate-lowering therapy titration to target decreases serum free fatty acids in gout and suppresses lipolysis by adipocytes. Arthritis research & therapy. 2022 Academic Article GET IT
Times cited: 1
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes. Nature. 2021 Academic Article GET IT
Times cited: 23
Chop/Ddit3 depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice. Science translational medicine. 2021 Academic Article GET IT
Times cited: 29
FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes. Cell reports. 2021 Academic Article GET IT
Times cited: 33
FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition. The Journal of clinical investigation. 2021 Academic Article GET IT
Times cited: 5
TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation. Cell metabolism. 2020 Academic Article GET IT
Times cited: 35
Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3. Nature metabolism. 2020 Academic Article GET IT
Times cited: 20
YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. Proceedings of the National Academy of Sciences of the United States of America. 2019 Academic Article GET IT
Times cited: 16
Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity. Bioorganic & medicinal chemistry. 2018 Academic Article GET IT
Times cited: 24
Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition. Molecular pharmacology. 2018 Academic Article GET IT
Times cited: 29
RalA controls glucose homeostasis by regulating glucose uptake in brown fat. Proceedings of the National Academy of Sciences of the United States of America. 2018 Academic Article GET IT
Times cited: 31
Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1-mediated p62/sequestosome 1 phosphorylation. Hepatology (Baltimore, Md.). 2018 Academic Article GET IT
Times cited: 60
ERRγ Preserves Brown Fat Innate Thermogenic Activity. Cell reports. 2018 Academic Article GET IT
Times cited: 23
TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue. Cell. 2018 Academic Article GET IT
Times cited: 165
Adapting to obesity with adipose tissue inflammation. Nature reviews. Endocrinology. 2017 Review GET IT
Times cited: 694
Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes. Cell metabolism. 2017 Academic Article GET IT
Times cited: 110
A futile approach to fighting obesity?. Cell. 2015 Comment GET IT
Times cited: 2
A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis. Nature communications. 2015 Academic Article GET IT
Times cited: 70
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nature medicine. 2015 Academic Article GET IT
Times cited: 510
Countering inflammatory signals in obesity. Nature immunology. 2014 Comment GET IT
Times cited: 5
Obesity: A complex role for adipose tissue macrophages. Nature reviews. Endocrinology. 2014 Comment GET IT
Times cited: 10
Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1. eLife. 2013 Academic Article GET IT
Times cited: 101
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice. Nature medicine. 2013 Academic Article GET IT
Times cited: 335
Transcriptional repression of mitochondrial function in aging: a novel role for the silencing mediator of retinoid and thyroid hormone receptors co-repressor. Antioxidants & redox signaling. 2012 Review GET IT
Times cited: 6
Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration. Cell metabolism. 2010 Academic Article GET IT
Times cited: 40
Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation. The Journal of biological chemistry. 2010 Academic Article GET IT
Times cited: 113
Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell metabolism. 2008 Academic Article GET IT
Times cited: 557
PPAR delta as a therapeutic target in metabolic disease. FEBS letters. 2007 Review GET IT
Times cited: 143

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Research

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Funding awarded

Regulation of fatty acid metabolism in adipocytes awarded by National Institute of Diabetes & Digestive & Kidney Diseases Principal Investigator 2022 - 2025

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Background

education and training

Ph.D., Harvard University 2011
B.S., University of Massachusetts 2005

Contact

full name

Shannon Reilly

primary email

smr4005@med.cornell.edu

VIVO Weill Cornell Medical College

Shannon Reilly Assistant Professor of Metabolic Health in Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email