selected publications
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Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.
The Journal of clinical investigation.
2020
Academic Article
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Times cited: 4 -
Mitochondrial dysfunction in lung ageing and disease.
European respiratory review : an official journal of the European Respiratory Society.
2020
Review
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Times cited: 35 -
Hepcidin Is Essential for Alveolar Macrophage Function and Is Disrupted by Smoke in a Murine Chronic Obstructive Pulmonary Disease Model.
Journal of immunology (Baltimore, Md. : 1950).
2020
Academic Article
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Times cited: 10 -
Increased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS.
Scientific reports.
2020
Academic Article
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Times cited: 10 -
To "Fe"ed or Not to "Fe"ed: Iron Depletion Exacerbates Emphysema Development in Murine Smoke Model.
American journal of respiratory cell and molecular biology.
2020
Editorial Article
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Times cited: 1 -
Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing.
Science (New York, N.Y.).
2020
Academic Article
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Times cited: 62 -
Alveolar Macrophage Immunometabolism and Lung Function Impairment in Smoking and Chronic Obstructive Pulmonary Disease.
American journal of respiratory and critical care medicine.
2020
Letter
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Times cited: 30 -
Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort.
JCI insight.
2020
Academic Article
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Times cited: 24 -
Mitochondria: at the crossroads of regulating lung epithelial cell function in chronic obstructive pulmonary disease.
American journal of physiology. Lung cellular and molecular physiology.
2019
Review
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Times cited: 49 -
Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.
Nature communications.
2019
Academic Article
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Times cited: 68 -
ToF-SIMS mediated analysis of human lung tissue reveals increased iron deposition in COPD (GOLD IV) patients.
Scientific reports.
2019
Academic Article
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Times cited: 14 -
Fatty acid synthase downregulation contributes to acute lung injury in murine diet-induced obesity.
JCI insight.
2019
Academic Article
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Times cited: 16 -
Do sputum or circulating blood samples reflect the pulmonary transcriptomic differences of COPD patients? A multi-tissue transcriptomic network META-analysis.
Respiratory research.
2019
Review
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Times cited: 8 -
Mitochondrial Iron in Human Health and Disease.
Annual review of physiology.
2018
Review
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Times cited: 72 -
Beclin-1 regulates cigarette smoke-induced kidney injury in a murine model of chronic obstructive pulmonary disease.
JCI insight.
2018
Academic Article
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Times cited: 15 -
Smoking-induced iron dysregulation in the lung.
Free radical biology & medicine.
2018
Review
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Times cited: 26 -
Circulating RIPK3 levels are associated with mortality and organ failure during critical illness.
JCI insight.
2018
Academic Article
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Times cited: 24 -
Autophagy and inflammation in chronic respiratory disease.
Autophagy.
2018
Review
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Times cited: 254 -
In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions.
Human molecular genetics.
2018
Academic Article
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Times cited: 50 -
Circulating Mitochondrial DNA as a Mechanism-based, Prognostic Biomarker for Idiopathic Pulmonary Fibrosis.
American journal of respiratory and critical care medicine.
2017
Editorial Article
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Times cited: 3 -
Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue.
Scientific reports.
2017
Academic Article
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Times cited: 61 -
Mitochondria in lung disease.
The Journal of clinical investigation.
2016
Review
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Times cited: 162 -
Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice.
Nature medicine.
2016
Academic Article
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Times cited: 163 -
Detailed Biological Profiling of a Photoactivated and Apoptosis Inducing pdppz Ruthenium(II) Polypyridyl Complex in Cancer Cells.
Journal of medicinal chemistry.
2015
Academic Article
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Times cited: 72 -
Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD.
The Journal of clinical investigation.
2014
Academic Article
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Times cited: 395 -
Synthesis and antiproliferative action of a novel series of maprotiline analogues.
European journal of medicinal chemistry.
2013
Academic Article
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Times cited: 12 -
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.
The Journal of clinical investigation.
2013
Academic Article
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Times cited: 232 -
Autophagy: a crucial moderator of redox balance, inflammation, and apoptosis in lung disease.
Antioxidants & redox signaling.
2013
Review
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Times cited: 76 -
Mitochondria: sensors and mediators of innate immune receptor signaling.
Current opinion in microbiology.
2013
Review
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Times cited: 50 -
Autophagy: a critical regulator of cellular metabolism and homeostasis.
Molecules and cells.
2013
Review
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Times cited: 239 -
The emerging importance of autophagy in pulmonary diseases.
Chest.
2012
Review
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Times cited: 100 -
Therapeutic potential of heme oxygenase-1/carbon monoxide in lung disease.
International journal of hypertension.
2012
Academic Article
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Times cited: 59 -
Self-assembly of hybrid organic-inorganic polyoxovanadates: functionalised mixed-valent clusters and molecular cages.
Dalton transactions (Cambridge, England : 2003).
2012
Academic Article
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Times cited: 45 -
Mitochondria: commanders of innate immunity and disease?.
Current opinion in immunology.
2011
Review
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Times cited: 64 -
Luminescent ruthenium(II) polypyridyl functionalized gold nanoparticles; their DNA binding abilities and application as cellular imaging agents.
Journal of the American Chemical Society.
2011
Academic Article
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Times cited: 138 -
Synthesis and serotonin transporter activity of 1,3-bis(aryl)-2-nitro-1-propenes as a new class of anticancer agents.
Bioorganic & medicinal chemistry.
2010
Academic Article
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Times cited: 22 -
Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce cell cycle arrest and apoptosis in prostate cancer cells.
Oncology reports.
2010
Academic Article
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Times cited: 10 -
Quaternarized pdppz: synthesis, DNA-binding and biological studies of a novel dppz derivative that causes cellular death upon light irradiation.
Chemical communications (Cambridge, England).
2010
Academic Article
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Times cited: 36 -
The antidepressants maprotiline and fluoxetine induce Type II autophagic cell death in drug-resistant Burkitt's lymphoma.
International journal of cancer.
2010
Academic Article
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Times cited: 80 -
Synthesis and in vitro toxicity of 4-MTA, its characteristic clandestine synthesis byproducts and related sulfur substituted alpha-alkylthioamphetamines.
Bioorganic & medicinal chemistry.
2010
Academic Article
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Times cited: 9 -
The antidepressants maprotiline and fluoxetine have potent selective antiproliferative effects against Burkitt lymphoma independently of the norepinephrine and serotonin transporters.
Leukemia & lymphoma.
2010
Academic Article
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Times cited: 40 -
Synthesis and serotonin transporter activity of sulphur-substituted alpha-alkyl phenethylamines as a new class of anticancer agents.
European journal of medicinal chemistry.
2009
Academic Article
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Times cited: 20 -
Identification of tubulin as the molecular target of proapoptotic pyrrolo-1,5-benzoxazepines.
Molecular pharmacology.
2006
Academic Article
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Times cited: 58