Josefowicz, Steven Zvi

Publications

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Co-Author Network

selected publications

Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing. bioRxiv : the preprint server for biology. 2023 Article GET IT
Angiopoietin 2 Is Associated with Vascular Necroptosis Induction in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome. The American journal of pathology. 2022 Academic Article GET IT
Times cited: 11
Publisher Correction: Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability. Nature cell biology. 2022 Article GET IT
Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability. Nature cell biology. 2021 Academic Article GET IT
Times cited: 7
Epigenetic and transcriptional control of interferon-β. The Journal of experimental medicine. 2021 Academic Article GET IT
Times cited: 5
Signaling-to-chromatin pathways in the immune system. Immunological reviews. 2021 Review GET IT
Times cited: 5
HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies. Cell reports. 2021 Academic Article GET IT
Times cited: 30
Histone H3.3 phosphorylation amplifies stimulation-induced transcription. Nature. 2020 Academic Article GET IT
Times cited: 61
Gene regulatory networks STARR-ing B cells. Nature immunology. 2020 Comment GET IT
Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome. Molecular cell. 2018 Academic Article GET IT
Times cited: 10
Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription. Molecular cell. 2016 Academic Article GET IT
Times cited: 48
Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome. Molecular cell. 2016 Review GET IT
Times cited: 100
An Interactive Database for the Assessment of Histone Antibody Specificity. Molecular cell. 2015 Academic Article GET IT
Times cited: 117
Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution. Science (New York, N.Y.). 2014 Academic Article GET IT
Times cited: 174
A comparative encyclopedia of DNA elements in the mouse genome. Nature. 2014 Academic Article GET IT
Times cited: 1071
Regulators of chromatin state and transcription in CD4 T-cell polarization. Immunology. 2013 Review GET IT
Times cited: 22
Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification. Cell. 2012 Academic Article GET IT
Times cited: 353
Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict. Cell. 2012 Academic Article GET IT
Times cited: 463
Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature. 2012 Academic Article GET IT
Times cited: 644
Regulatory T cells: mechanisms of differentiation and function. Annual review of immunology. 2012 Review GET IT
Times cited: 2036
Stability of the regulatory T cell lineage in vivo. Science (New York, N.Y.). 2010 Academic Article GET IT
Times cited: 529
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature. 2010 Academic Article GET IT
Times cited: 884
Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1. Journal of immunology (Baltimore, Md. : 1950). 2009 Academic Article GET IT
Times cited: 130
Control of regulatory T cell lineage commitment and maintenance. Immunity. 2009 Review GET IT
Times cited: 458
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature. 2007 Academic Article GET IT
Times cited: 702
CMV antigen-specific CD4+ and CD8+ T cell IFNgamma expression and proliferation responses in healthy CMV-seropositive individuals. Viral immunology. 2004 Academic Article GET IT
Times cited: 30

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Research

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Funding awarded

Epigenetic regulation of immunity: molecular mechanisms of inflammatory priming and altered hematopoiesis awarded by Burroughs Wellcome Fund Principal Investigator 2022 - 2027
Mechanisms of dynamic chromatin reorganization regulating B-cell differentiation and Lymphomagenesis awarded by Starr Cancer Consortium Principal Investigator 2023 - 2024
Epigenetic alterations and phenotypes in innate immune cells and their progenitors in PASC awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2022 - 2024
Cooption of the DNA Damage Response For Epigenetic Regulation of Inflammation awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2019 - 2024
Addgene 704323 awarded by Addgene, Inc. Principal Investigator 2022 - 2023
Epigenetic Priming of Inflammatory Genes in COVID-19: Insights into Pathogenesis and Prognosis awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2020 - 2023

Impact of SARS-CoV-2 infection on respiratory viral immune responses in children with and without asthma awarded by National Institute of Allergy & Infectious Diseases Co-Investigator 2023 - 2028
ASH award awarded by American Society of Hematology Inc Co-Investigator 2022 - 2024
Immune Cells and Secretory Pathways Leading to Human Systemic Autoimmunity awarded by National Institute of Allergy & Infectious Diseases Co-Investigator 2019 - 2024
The Mark Foundation ASPIRE Phase II Proposal awarded by The Mark Foundation for Cancer Research Co-Investigator 2020 - 2023
Immune Cells and Secretory Pathways Leading to Human Systemic Autoimmunity awarded by National Institute of Allergy & Infectious Diseases Co-Investigator 2020 - 2023

Structure, Function, and Dynamics of Macro-molecular Complexes that Execute and Regulate Genome Function awarded by National Institute of General Medical Sciences Key Personnel 2021 - 2026
Describing the Epigenetic Mechanisms in Control of Hematopoietic Development and Rapid Inflammatory Responses awarded by National Heart, Lung, & Blood Institute Key Personnel 2021 - 2024

Structure, Function, and Dynamics of Large Molecular Complexes that Execute and Regulate Genome Function awarded by National Institute of General Medical Sciences Principal Investigator Subaward 2021 - 2026
Quantitative mapping of dynamic epigenetic states in rare and stimulated immune cells awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2022 - 2025
Leveraging functional genomics to create an epigenetic toolbox for inflammation research and drug discovery awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2021 - 2024

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Background

education and training

Ph.D., University of Washington 2010
B.A., University of California, Berkeley 2002

Contact

full name

Steven Zvi Josefowicz

primary email

szj2001@med.cornell.edu

VIVO Weill Cornell Medical College

Steven Zvi Josefowicz Associate Professor of Pathology and Laboratory Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email