selected publications
- Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis. mBio. 2023 Academic Article GET IT
- Synthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation. bioRxiv : the preprint server for biology. 2023 Article GET IT
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Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis.
eLife.
2023
Academic Article
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Times cited: 55 -
Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection.
Nature communications.
2021
Academic Article
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Times cited: 9 -
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development.
Nature communications.
2019
Academic Article
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Times cited: 57 -
Chassis optimization as a cornerstone for the application of synthetic biology based strategies in microbial secondary metabolism.
Frontiers in microbiology.
2015
Review
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Times cited: 25 -
Streptomyces natalensis programmed cell death and morphological differentiation are dependent on oxidative stress.
Scientific reports.
2015
Academic Article
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Times cited: 24 -
Genome-wide analysis of the regulation of pimaricin production in Streptomyces natalensis by reactive oxygen species.
Applied microbiology and biotechnology.
2014
Academic Article
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Times cited: 11 -
Crosstalk between ROS homeostasis and secondary metabolism in S. natalensis ATCC 27448: modulation of pimaricin production by intracellular ROS.
PloS one.
2011
Academic Article
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Times cited: 33