selected publications
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Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer.
The Journal of experimental medicine.
2022
Academic Article
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Times cited: 3 -
PPP6C, a serine-threonine phosphatase, regulates melanocyte differentiation and contributes to melanoma tumorigenesis through modulation of MITF activity.
Scientific reports.
2022
Academic Article
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Times cited: 2 -
RET Fusion-Positive Papillary Thyroid Cancers are Associated with a More Aggressive Phenotype.
Annals of surgical oncology.
2022
Academic Article
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Times cited: 243 -
Histone 3 Methyltransferases Alter Melanoma Initiation and Progression Through Discrete Mechanisms.
Frontiers in cell and developmental biology.
2022
Academic Article
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Times cited: 62 -
Validation of a Circulating Tumor DNA-Based Next-Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing.
The oncologist.
2021
Academic Article
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Times cited: 6 -
Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood.
The Journal of clinical investigation.
2020
Academic Article
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Times cited: 17 -
Synthetic CRISPR/Cas9 reagents facilitate genome editing and homology directed repair.
Nucleic acids research.
2020
Academic Article
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Times cited: 24 -
Oxidative Phosphorylation Promotes Primary Melanoma Invasion.
The American journal of pathology.
2020
Academic Article
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Times cited: 13 -
Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer.
Nature genetics.
2019
Academic Article
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Times cited: 35 -
Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes.
Gastroenterology.
2019
Academic Article
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Times cited: 56 -
Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth.
The EMBO journal.
2018
Academic Article
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Times cited: 57 -
Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma.
The Journal of clinical investigation.
2017
Academic Article
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Times cited: 31 -
Identification and characterization of T reg-like cells in zebrafish.
The Journal of experimental medicine.
2017
Academic Article
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Times cited: 54 -
Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression.
eLife.
2017
Academic Article
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Times cited: 42 -
Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America.
2016
Academic Article
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Times cited: 35 -
Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth.
Nature cell biology.
2016
Academic Article
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Times cited: 132 -
Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish.
Nature communications.
2016
Academic Article
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Times cited: 70 -
Uncharted Waters: Zebrafish Cancer Models Navigate a Course for Oncogene Discovery.
Advances in experimental medicine and biology.
2016
Review
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Times cited: 2 -
SPOP mutation leads to genomic instability in prostate cancer.
eLife.
2015
Academic Article
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Times cited: 129 - Multiplexing of ChIP-Seq Samples in an Optimized Experimental Condition Has Minimal Impact on Peak Detection. PloS one. 2015 Academic Article GET IT
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RSK1 activation promotes invasion in nodular melanoma.
The American journal of pathology.
2015
Academic Article
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Times cited: 21 -
Optimized cell transplantation using adult rag2 mutant zebrafish.
Nature methods.
2014
Academic Article
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Times cited: 104 -
Efatutazone, an oral PPAR-γ agonist, in combination with paclitaxel in anaplastic thyroid cancer: results of a multicenter phase 1 trial.
The Journal of clinical endocrinology and metabolism.
2013
Academic Article
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Times cited: 85 -
Screening for melanoma modifiers using a zebrafish autochthonous tumor model.
Journal of visualized experiments : JoVE.
2012
Academic Article
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Times cited: 23 -
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.
Cell.
2012
Academic Article
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Times cited: 612 -
Completing the Arc: targeted inhibition of RET in medullary thyroid cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2011
Comment
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Times cited: 17 -
Hooked on zebrafish: insights into development and cancer of endocrine tissues.
Endocrine-related cancer.
2011
Review
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Times cited: 11 -
Cabozantinib in medullary thyroid carcinoma: time to focus the spotlight on this rare disease.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2011
Editorial Article
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Times cited: 8 -
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset.
Nature.
2011
Academic Article
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Times cited: 400 -
Melanoma biology and the promise of zebrafish.
Zebrafish.
2008
Review
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Times cited: 37 -
The effect of a depth gradient on the mating behavior, oviposition site preference, and embryo production in the zebrafish, Danio rerio.
Zebrafish.
2008
Academic Article
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Times cited: 33 -
BRCA1 physically and functionally interacts with ATF1.
The Journal of biological chemistry.
2000
Academic Article
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Times cited: 52 -
Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.
Nature.
1997
Academic Article
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Times cited: 472