Arteriosclerosis, thrombosis, and vascular biology

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Molecular basis of fish-eye disease in a patient from Spain. Characterization of a novel mutation in the LCAT gene and lipid analysis of the cornea. 1997
Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis.. 42. 2022
High Free Cholesterol Bioavailability Drives the Tissue Pathologies in Scarb1^-/- Mice.. 41. 2021
Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1.. 40. 2020
¹⁸F-Sodium Fluoride Positron Emission Tomography/Computed Tomography in Ex Vivo Human Coronary Arteries With Histological Correlation.. 40. 2019
TLR4 (Toll-Like Receptor 4)-Dependent Signaling Drives Extracellular Catabolism of LDL (Low-Density Lipoprotein) Aggregates.. 40. 2019
Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques.. 39. 2019
Inflammasome Signaling and Impaired Vascular Health in Psoriasis.. 39. 2019
Dynamic Actin Reorganization and Vav/Cdc42-Dependent Actin Polymerization Promote Macrophage Aggregated LDL (Low-Density Lipoprotein) Uptake and Catabolism.. 39. 2019
MicroRNA-199a-3p and MicroRNA-199a-5p Take Part to a Redundant Network of Regulation of the NOS (NO Synthase)/NO Pathway in the Endothelium.. 38. 2018
Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research.. 38. 2018
ABCA1-Derived Nascent High-Density Lipoprotein-Apolipoprotein AI and Lipids Metabolically Segregate.. 37. 2017
Loss of Transcription Factor CREBH Accelerates Diet-Induced Atherosclerosis in Ldlr-/- Mice.. 36. 2016
Walking and Calcified Atherosclerotic Plaque in the Coronary Arteries: The National Heart, Lung, and Blood Institute Family Heart Study.. 36. 2016
Smooth Muscle Hypoxia-Inducible Factor 1α Links Intravascular Pressure and Atherosclerosis--Brief Report.. 36. 2016
The Protein Acyl Transferase ZDHHC21 Modulates α1 Adrenergic Receptor Function and Regulates Hemodynamics.. 36. 2015
Monocyte-Derived Dendritic Cells Upregulate Extracellular Catabolism of Aggregated Low-Density Lipoprotein on Maturation, Leading to Foam Cell Formation.. 35. 2015
Inhibition of ERK1/2 and activation of LXR synergistically reduce atherosclerotic lesions in ApoE-deficient mice.. 35. 2015
Shear stress-activated Wnt-angiopoietin-2 signaling recapitulates vascular repair in zebrafish embryos.. 34. 2014
CXCR3 controls T-cell accumulation in fat inflammation.. 34. 2014
Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein.. 33. 2013
Impaired lipoprotein processing in HIV patients on antiretroviral therapy: aberrant high-density lipoprotein lipids, stability, and function.. 33. 2013
Conversion of human fibroblasts to functional endothelial cells by defined factors.. 33. 2013
Polymorphism in endothelial connexin40 enhances sensitivity to intraluminal pressure and increases arterial stiffness.. 33. 2013
Heritability of venous biomechanics.. 33. 2012
Myeloid deletion of nuclear factor erythroid 2-related factor 2 increases atherosclerosis and liver injury.. 32. 2012
Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease.. 31. 2011
Nucleotide-binding oligomerization domain protein 2 deficiency enhances neointimal formation in response to vascular injury.. 31. 2011
Apolipoprotein E mediates enhanced plasma high-density lipoprotein cholesterol clearance by low-dose streptococcal serum opacity factor via hepatic low-density lipoprotein receptors in vivo.. 31. 2011
Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice.. 31. 2011
Macrophage activation is responsible for loss of anticontractile function in inflamed perivascular fat.. 31. 2011
Targeted Vezf1-null mutation impairs vascular structure formation during embryonic stem cell differentiation.. 30. 2010
Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion.. 30. 2010
Absence of Akt1 reduces vascular smooth muscle cell migration and survival and induces features of plaque vulnerability and cardiac dysfunction during atherosclerosis.. 29. 2009
Aggregated LDL in contact with macrophages induces local increases in free cholesterol levels that regulate local actin polymerization.. 29. 2009
Dimethylarginine dimethylaminohydrolase overexpression enhances insulin sensitivity.. 28. 2008
Suppressing PTEN activity by tobacco smoke plus interleukin-1beta modulates dissociation of VE-cadherin/beta-catenin complexes in endothelium.. 28. 2008
Differential regulation of homocysteine transport in vascular endothelial and smooth muscle cells.. 27. 2007
Elevated cholesterol levels in the plasma membranes of macrophages inhibit migration by disrupting RhoA regulation.. 27. 2007
Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN.. 27. 2007
Cerebrovascular nitrosative stress mediates neurovascular and endothelial dysfunction induced by angiotensin II.. 27. 2006
In vivo plaque characterization using intravascular ultrasound-virtual histology in a porcine model of complex coronary lesions.. 27. 2006
A central role for nicotinic cholinergic regulation of growth factor-induced endothelial cell migration.. 27. 2006
Quantitation and localization of matrix metalloproteinases and their inhibitors in human carotid endarterectomy tissues.. 26. 2006
HSPA12B is predominantly expressed in endothelial cells and required for angiogenesis.. 26. 2006
Intrinsic fluorescence and diffuse reflectance spectroscopy identify superficial foam cells in coronary plaques prone to erosion.. 26. 2006
Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2-derived radicals.. 26. 2006
Elevated plasma membrane cholesterol content alters macrophage signaling and function.. 26. 2005
Hyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation.. 25. 2005
Proteinase-activated receptor-2 mediates arterial vasodilation in diabetes.. 25. 2005
Effect of P-selectin on phosphatidylserine exposure and surface-dependent thrombin generation on monocytes.. 25. 2005
Exogenous NADPH increases cerebral blood flow through NADPH oxidase-dependent and -independent mechanisms.. 24. 2004
Stable compounds of cigarette smoke induce endothelial superoxide anion production via NADPH oxidase activation.. 24. 2004
Diabetic mouse angiopathy is linked to progressive sympathetic receptor deletion coupled to an enhanced caveolin-1 expression.. 24. 2004
Isolation, characterization, and functional assessment of oxidatively modified subfractions of circulating low-density lipoproteins.. 23. 2003
In silico quantitative trait locus map for atherosclerosis susceptibility in apolipoprotein E-deficient mice.. 23. 2003
Endothelial determinants of dendritic cell adhesion and migration: new implications for vascular diseases.. 22. 2002
HIV protease inhibitor ritonavir induces cytotoxicity of human endothelial cells.. 22. 2002
Heritability of carotid artery structure and function: the Strong Heart Family Study.. 22. 2002
In memoriam Donald S. Fredrickson, MD: 1924-2002.. 22. 2002
Genetic influences on aortic root size in American Indians: the Strong Heart Study .. 22. 2002
Adhesion of monocytes to arterial endothelium and initiation of atherosclerosis are critically dependent on vascular cell adhesion molecule-1 gene dosage.. 21. 2001
Relation of blood pressure variability to carotid atherosclerosis and carotid artery and left ventricular hypertrophy.. 21. 2001
Regulation of acyl-coenzyme A:cholesterol acyltransferase (ACAT) synthesis, degradation, and translocation by high-density lipoprotein(2) at a low concentration.. 20. 2000
Replication of linkage of familial combined hyperlipidemia to chromosome 1q with additional heterogeneous effect of apolipoprotein A-I/C-III/A-IV locus. The NHLBI Family Heart Study.. 20. 2000
Enrichment of acyl coenzyme A:cholesterol O-acyltransferase near trans-golgi network and endocytic recycling compartment.. 20. 2000
Quantification in situ of crystalline cholesterol and calcium phosphate hydroxyapatite in human atherosclerotic plaques by solid-state magic angle spinning NMR.. 20. 2000
Asymmetric dimethylarginine increases mononuclear cell adhesiveness in hypercholesterolemic humans.. 20. 2000
Genetic localization to chromosome 1p32 of the third locus for familial hypercholesterolemia in a Utah kindred.. 20. 2000
LDL cholesterol as a strong predictor of coronary heart disease in diabetic individuals with insulin resistance and low LDL: The Strong Heart Study.. 20. 2000
Nitric oxide induces the synthesis of vascular endothelial growth factor by rat vascular smooth muscle cells.. 20. 2000
Carotid intimal-medial thickness and stiffness are not affected by hypercholesterolemia in uncomplicated essential hypertension.. 19. 1999
Platelet-derived growth factor stimulates heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells.. 19. 1999
Efficient nuclear delivery of antisense oligodeoxynucleotides and selective inhibition of CETP expression by apo E peptide in a human CETP-stably transfected CHO cell line.. 19. 1999
NGF activates similar intracellular signaling pathways in vascular smooth muscle cells as PDGF-BB but elicits different biological responses.. 19. 1999
Interaction of diabetes and hypertension on determinants of endothelial adhesiveness.. 18. 1998
Soluble cell adhesion molecules in hypertriglyceridemia and potential significance on monocyte adhesion.. 18. 1998
Adhesiveness of mononuclear cells in hypercholesterolemic humans is normalized by dietary L-arginine.. 17. 1997
Calreticulin, a potential vascular regulatory protein, reduces intimal hyperplasia after arterial injury.. 17. 1997
Lipoprotein(a) interactions with lipid and nonlipid risk factors in early familial coronary artery disease.. 17. 1997
Evidence for prolonged cell-surface contact of acetyl-LDL before entry into macrophages.. 17. 1997
Inhibitory effects of hypercholesterolemia and ox-LDL on angiogenesis-like endothelial growth in rabbit aortic explants. Essential role of basic fibroblast growth factor.. 17. 1997
Effective lowering of plasma, LDL, and esterified cholesterol in LDL receptor-knockout mice by adenovirus-mediated gene delivery of ApoB mRNA editing enzyme (Apobec1).. 17. 1997
Apolipoprotein E polymorphism in American Indians and its relation to plasma lipoproteins and diabetes. The Strong Heart Study.. 16. 1996
Evidence for a major gene elevating serum bilirubin concentration in Utah pedigrees.. 16. 1996
Apolipoprotein A-II influences the substrate properties of human HDL2 and HDL3 for hepatic lipase.. 16. 1996
Higher serum bilirubin is associated with decreased risk for early familial coronary artery disease.. 16. 1996
Regression or progression. Dependency on vascular nitric oxide.. 16. 1996
Higher plasma homocyst(e)ine and increased susceptibility to adverse effects of low folate in early familial coronary artery disease.. 15. 1995
Oxidized LDL binds to CD36 on human monocyte-derived macrophages and transfected cell lines. Evidence implicating the lipid moiety of the lipoprotein as the binding site.. 15. 1995
Incidence and Outcomes of Thrombotic Events in Symptomatic Patients With COVID-19. 2020
A peculiar result and a fanciful hypothesis regarding L-arginine. 2003
Commentary on fatty acid wars: the diffusionists versus the translocatists.. 34. 2014
DDAH says NO to ADMA.. 31. 2011
Aortic stenosis and statins: more evidence of "pleotropy"?. 25. 2005
Atherosclerosis and neurodegeneration: unexpected conspirators in Alzheimer's dementia.. 23. 2003
Infection and atherosclerosis: potential roles of pathogen burden and molecular mimicry.. 20. 2000
Oxidized lipoproteins and infectious agents: are they in collusion to accelerate atherogenesis?. 20. 2000
Molecular Mechanisms of Vascular Health: Insights From Vascular Aging and Calcification. 2022
Pathologic Disparities Between Peripheral Artery Disease and Coronary Artery Disease. 2020
Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop: Focus on Cardiovascular Disease. 2019
Differentiation, Evaluation, and Application of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells. 2017
ABO Blood Group as a Model for Platelet Glycan Modification in Arterial Thrombosis. 2015
The emerging role of the thioredoxin system in angiogenesis. 2010
Regulation of hypoxia-inducible genes by PGC-1 alpha. 2009
Regulation of vasculogenesis by platelet-mediated recruitment of bone marrow-derived cells. 2007
Genetic susceptibility to peripheral arterial disease: a dark corner in vascular biology. 2007
RAGE axis: Animal models and novel insights into the vascular complications of diabetes. 2004
Cardiac allograft vasculopathy and dysregulation of the NO synthase pathway. 2003
Does ADMA cause endothelial dysfunction? 2000
Herpesvirus in atherosclerosis and thrombosis: etiologic agents or ubiquitous bystanders? 1998

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Arteriosclerosis, thrombosis, and vascular biology Journal

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