The tryptolines: effect of intraventricular administration on spontaneous motor activity of rats. Academic Article uri icon

Overview

abstract

  • The pharmacologic properties of the tryptolines, hindered analogues of the tryptamines, were studied behaviorally in rats. Following intraventricular injections, it was found that spontaneous motor activity decreased markedly during the initial 25 mins when compared with saline. Since both the tryptolines and tryptamines have been shown to be inhibitors of 5-hydroxytryptamine uptake, it may be possible that these compounds are acting indirectly throught an effect on the serotonergic system.

publication date

  • October 1, 1976

Research

keywords

  • Carbolines
  • Indoles
  • Motor Activity

Identity

Scopus Document Identifier

  • 0017043144

Digital Object Identifier (DOI)

  • 10.1016/0091-3057(76)90099-x

PubMed ID

  • 1005486

Additional Document Info

volume

  • 5

issue

  • 4