Leptin, neuropeptide Y, and peptide YY in long-term recovered eating disorder patients. Academic Article uri icon

Overview

abstract

  • BACKGROUND: Disturbances of leptin, neuropeptide Y (NPY), and peptide YY (PYY) have been found in women who are ill with anorexia or bulimia nervosa. It is not certain whether peptide disturbances are cause or consequence of eating disorders. METHODS: Plasma leptin and cerebrospinal fluid leptin, NPY, and PYY concentrations were measured in women who were recovered from anorexia or bulimia nervosa to determine whether alterations persisted after recovery. RESULTS: NPY, PYY, and leptin concentrations were similar across all diagnostic groups. CONCLUSIONS: Alterations in NPY, PYY, and serum leptin concentrations are probably secondary to pathological eating behaviors. Alterations of these peptides are unlikely to be trait-related disturbances that contribute to the etiology of eating disorders.

publication date

  • July 15, 1999

Research

keywords

  • Anorexia Nervosa
  • Bulimia
  • Convalescence
  • Neuropeptide Y
  • Peptide YY
  • Proteins

Identity

Scopus Document Identifier

  • 0033026175

Digital Object Identifier (DOI)

  • 10.1016/s0006-3223(98)00292-3

PubMed ID

  • 10418705

Additional Document Info

volume

  • 46

issue

  • 2