Executive functions and P300 latency in elderly depressed patients and control subjects. Academic Article uri icon

Overview

abstract

  • The authors asked whether impaired executive functioning and long P300 latency are related dysfunctions and whether they are associated with geriatric depression. A group of 25 elderly depressed patients without dementia and 20 control subjects were assessed on tasks of fluency, initiation and perseveration, the Stroop task, the Wisconsin Card Sorting Test (WCST) perseverative error score, and P300 latency. The groups' performance differed significantly on these tasks and in P300 latency. Longer latency was associated with poorer performance in both groups on all measures except WCST perseverative errors. Regardless of patients' depression status, increased P300 latency predicts poorer performance on executive function tasks requiring speeded performance.

publication date

  • January 1, 2000

Research

keywords

  • Cognition Disorders
  • Depressive Disorder, Major
  • Event-Related Potentials, P300

Identity

Scopus Document Identifier

  • 0033987485

Digital Object Identifier (DOI)

  • 10.1097/00019442-200002000-00008

PubMed ID

  • 10648296

Additional Document Info

volume

  • 8

issue

  • 1