Primary central nervous system lymphoma. Review uri icon

Overview

abstract

  • Primary central nervous system (CNS) lymphoma is an unusual but increasingly frequent brain tumor being identified by neurologists. Considerable improvements in survival have been accomplished by the addition of chemotherapy to cranial radiotherapy. In addition, many patients achieve substantial disease free survival with chemotherapy alone, and survival is superior to radiotherapy alone. Currently, every patient should be considered for chemotherapy as the first line of treatment. Subsequent cranial radiotherapy may or may not be necessary depending upon the patient's clinical condition, age and response to initial chemotherapy. Intensification of multi-agent chemotherapy is under study and it is anticipated that the incidence of neurotoxicity will reduce with elimination of combined modality treatment.

publication date

  • December 1, 1999

Research

keywords

  • Central Nervous System Neoplasms
  • Lymphoma

Identity

Scopus Document Identifier

  • 0033384367

Digital Object Identifier (DOI)

  • 10.1097/00019052-199912000-00005

PubMed ID

  • 10676749

Additional Document Info

volume

  • 12

issue

  • 6