The medullary cerebrovascular vasodilator area mediates cerebrovascular vasodilation and electroencephalogram synchronization elicited from cerebellar fastigial nucleus in Sprague-Dawley rats. Academic Article uri icon

Overview

abstract

  • We investigated whether the medullary cerebrovasodilator area (MCVA), a region of ventral medulla mediating elevations of regional cerebral blood flow (rCBF) and electroencephalogram (EEG) synchronization elicited in cerebral cortex from stimulation of reticulospinal neurons of rostral ventrolateral medulla (RVLM), also mediates comparable responses from the cerebellar fastigial nucleus (FN). In spinalized rats, electrical stimulation of MCVA, RVLM or FN elevated rCBF and synchronized the EEG. The FN-evoked responses were significantly attenuated or blocked by bilateral lesions of MCVA. The MCVA is a novel region of medullary reticular formation mediating actions of medullary and cerebellar centers on rCBF and EEG to link visceral centers of brainstem and cerebral cortex.

publication date

  • July 21, 2000

Research

keywords

  • Cerebellar Nuclei
  • Cortical Synchronization
  • Medulla Oblongata
  • Vasodilation

Identity

Scopus Document Identifier

  • 0034698488

Digital Object Identifier (DOI)

  • 10.1016/s0304-3940(00)01228-3

PubMed ID

  • 10889338

Additional Document Info

volume

  • 288

issue

  • 3