Direct ex vivo measurement of CD8(+) T-lymphocyte responses to human parvovirus B19. Academic Article uri icon

Overview

abstract

  • Parvovirus B19 is a common human pathogen which can cause severe syndromes, including aplastic anemia and fetal hydrops. The mapping of the first parvovirus B19-derived CD8(+) T-lymphocyte epitope is described. This HLA-B35-restricted peptide derives from the nonstructural (NS1) protein and is strongly immunogenic in B19 virus-seropositive donors.

publication date

  • January 1, 2001

Research

keywords

  • CD8-Positive T-Lymphocytes
  • Parvovirus B19, Human

Identity

PubMed Central ID

  • PMC113948

Scopus Document Identifier

  • 0034751163

Digital Object Identifier (DOI)

  • 10.1128/JVI.75.1.540-543.2001

PubMed ID

  • 11119624

Additional Document Info

volume

  • 75

issue

  • 1