Proton magnetic resonance spectroscopy of choroid plexus tumors in children. uri icon

Overview

abstract

  • A variety of lesions may present as intraventricular masses in children. We report quantitative proton magnetic resonance spectroscopy (MRS) of two intraventricular tumors of the choroid plexus: choroid plexus carcinoma (CPC) and choroid plexus papilloma (CPP). Both lesions were characterized by high levels of choline-containing compounds and a complete absence of creatine and the neuronal/axonal marker N-acetyl aspartate. The CPC showed higher levels of choline compared to the CPP, and it also had elevated lactate. These preliminary results, if confirmed in a larger cohort of patients, indicate that proton MRS may have a role in the presurgical diagnosis of choroid plexus tumors in children, which may also have important implications for therapy and prognosis.

publication date

  • July 1, 2001

Research

keywords

  • Choroid Plexus Neoplasms
  • Energy Metabolism
  • Magnetic Resonance Imaging
  • Magnetic Resonance Spectroscopy
  • Papilloma, Choroid Plexus

Identity

Scopus Document Identifier

  • 0034956975

Digital Object Identifier (DOI)

  • 10.1002/jmri.1154

PubMed ID

  • 11436218

Additional Document Info

volume

  • 14

issue

  • 1