Synthesis of nodulisporic acid 2' '-oxazoles and 2' '-thiazoles. Academic Article uri icon

Overview

abstract

  • [reaction--see text] The semisynthetic conversion of nodulisporic acid A (1) into a set of three heterocyclic side chain derivatives provided compounds, highlighted by 6, with an improved spectrum of ectoparasiticidal activity and pharmacokinetic profile relative to the natural product.

publication date

  • November 15, 2001

Research

keywords

  • Indoles
  • Insecticides
  • Oxazoles
  • Thiazoles

Identity

Scopus Document Identifier

  • 18044399538

Digital Object Identifier (DOI)

  • 10.1021/ol016651x

PubMed ID

  • 11700120

Additional Document Info

volume

  • 3

issue

  • 23