Neurobehavioral deficits in premature graduates of intensive care--potential medical and neonatal environmental risk factors. Review uri icon

Overview

abstract

  • There is growing evidence that a large number of very low birth weight infants are exhibiting neurobehavioral problems in the absence of cerebral palsy at follow-up that has extended into school age and adolescence. Many clinical factors (ie, chronic lung disease, recurrent apnea and bradycardia, transient hypothyroxemia of prematurity, hyperbilirubinemia, nutritional deficiencies, glucocorticoid exposure), as well as stressful environmental conditions, including infant-provider interaction, constant noise, and bright light, may act in combination to impact on the developing brain, even in the absence of overt hemorrhage and/or ischemia. Any potential intervention strategy designed to prevent cognitive and behavioral problems has to account for the numerous biological and clinical conditions and/or interventions, as well as postdischarge social and environmental influences.

publication date

  • December 1, 2001

Research

keywords

  • Attention Deficit and Disruptive Behavior Disorders
  • Child Behavior Disorders
  • Cognition Disorders
  • Infant, Premature
  • Infant, Premature, Diseases
  • Infant, Very Low Birth Weight
  • Intensive Care, Neonatal

Identity

Scopus Document Identifier

  • 0035199085

Digital Object Identifier (DOI)

  • 10.1542/peds.108.6.1339

PubMed ID

  • 11731657

Additional Document Info

volume

  • 108

issue

  • 6