Granulomatous and suppurative dermatitis at interferon alfa injection sites: report of 2 cases. uri icon

Overview

abstract

  • It has previously been reported that interferon alfa injection sites may develop pyoderma gangrenosum, interface dermatitis, vasculitis, or, more commonly, ulcers characterized by intravascular thrombi and a mixed inflammatory cell infiltrate. We describe 2 patients in whom granulomatous and suppurative dermatitis developed at interferon alfa injection sites. These cases extend the spectrum of interferon alfa injection site reactions. The histologic and clinical similarities of these cases with pyoderma gangrenosum and cutaneous Crohn's disease are explored.

publication date

  • April 1, 2002

Research

keywords

  • Granuloma
  • Injections, Subcutaneous
  • Interferon-alpha
  • Skin Diseases

Identity

Scopus Document Identifier

  • 0036553577

Digital Object Identifier (DOI)

  • 10.1067/mjd.2002.119087

PubMed ID

  • 11907520

Additional Document Info

volume

  • 46

issue

  • 4