Synthesis of side chain truncated 3"-aldehyde, 3"-carboxylic acid, and 1"-aldehyde from nodulisporic acid A. Academic Article uri icon

Overview

abstract

  • An efficient synthesis of the truncated 3"-aldehyde (3) from nodulisporic acid A (1) under mild conditions is described. Further oxidation of 3 to 3"-carboxylic acid (4) and its subsequent oxidative degradation produced 1"-aldehyde (5). These new derivatives are versatile intermediates for the preparation of new, side chain modified derivatives of nodulisporic acid A. [reaction: see text]

publication date

  • April 18, 2002

Research

keywords

  • Aldehydes
  • Carboxylic Acids
  • Indoles
  • Insecticides

Identity

Scopus Document Identifier

  • 0037129410

Digital Object Identifier (DOI)

  • 10.1021/ol025766d

PubMed ID

  • 11950345

Additional Document Info

volume

  • 4

issue

  • 8