Varicella-zoster virus: mechanisms of pathogenicity and corneal disease. Review uri icon

Overview

abstract

  • As ophthalmologists, many of our patients suffer from the ravages, both ocular and non-ocular, of the varicella-zoster virus. This article is a comprehensive review of the pathogenetic mechanisms of this ubiquitous virus. We review the basic virology, mechanisms of varicella, zoster, latency, reactivation, and the host immune response to the virus. Herpes zoster ophthalmicus is discussed with special attention to the cornea and mechanisms of viral keratitis.

publication date

  • March 1, 2002

Research

keywords

  • Corneal Diseases
  • Herpes Zoster Ophthalmicus
  • Herpesvirus 3, Human

Identity

Scopus Document Identifier

  • 0036263816

Digital Object Identifier (DOI)

  • 10.1016/s0896-1549(01)00006-2

PubMed ID

  • 12064084

Additional Document Info

volume

  • 15

issue

  • 1