Donepezil and flight simulator performance: effects on retention of complex skills. Academic Article uri icon

Overview

abstract

  • We report a randomized, double-blind, parallel group, placebo-controlled study to test the effects of the acetylcholinesterase inhibitor, donepezil (5 mg/d for 30 days), on aircraft pilot performance in 18 licensed pilots with mean age of 52 years. After 30 days of treatment, the donepezil group showed greater ability to retain the capacity to perform a set of complex simulator tasks than the placebo group, p < 0.05. Donepezil appears to have beneficial effects on retention of training on complex aviation tasks in nondemented older adults.

publication date

  • July 9, 2002

Research

keywords

  • Cholinesterase Inhibitors
  • Indans
  • Motor Skills
  • Piperidines

Identity

Scopus Document Identifier

  • 0037046984

Digital Object Identifier (DOI)

  • 10.1212/wnl.59.1.123

PubMed ID

  • 12105320

Additional Document Info

volume

  • 59

issue

  • 1