Cognitive dysfunction in neuropsychiatric systemic lupus erythematosus. Review uri icon

Overview

abstract

  • Neuropsychiatric syndromes associated with systemic lupus erythematosus are common, but diverse in etiology and presentation. Cognitive dysfunction is prevalent among these syndromes, but exhibit a significant degree of heterogeneity both within and between patient variability. Earlier studies of SLE-associated cognitive dysfunction addressed its identification and description. Common associations were repeatedly acknowledged, including concomitant or past neuropsychiatric disease, use of corticosteroids, disease activity, emotional disturbance, and antiphospholipid antibodies. The past several years have focused more on elucidating the relative strengths of various risk associations, patterns of cognitive abnormalities, both cross-sectionally and longitudinally (, clinical course), and novel means to identify cognitive impairment, both functionally and biologically.

publication date

  • September 1, 2002

Research

keywords

  • Cognition Disorders
  • Lupus Vasculitis, Central Nervous System

Identity

Scopus Document Identifier

  • 0036707747

Digital Object Identifier (DOI)

  • 10.1097/00002281-200209000-00005

PubMed ID

  • 12192246

Additional Document Info

volume

  • 14

issue

  • 5