Pythium insidiosum pleuropericarditis complicating pneumonia in a child with leukemia. uri icon

Overview

abstract

  • We describe a 12-year-old boy with acute myeloid leukemia who developed pleuropericarditis while he was neutropenic and was receiving intravenously administered antibiotic and antifungal therapy for pneumonia. A KOH preparation of the purulent material from an extensive diagnostic and therapeutic pleuropericardial drainage procedure revealed multiple irregularly septate hyphae, and cultures yielded the organism Pythium insidiosum. After completing a 12-month course of intravenously administered liposomal amphotericin B (AmBisome; Fujisawa Healthcare) and itraconazole, the patient remained alive, in clinical remission, and symptom free.

publication date

  • August 23, 2002

Research

keywords

  • Leukemia, Myeloid, Acute
  • Pericarditis
  • Pneumonia
  • Pythium

Identity

Scopus Document Identifier

  • 19044380016

Digital Object Identifier (DOI)

  • 10.1086/342303

PubMed ID

  • 12203186

Additional Document Info

volume

  • 35

issue

  • 6