Alteplase in the treatment of complicated parapneumonic effusion: a case report. uri icon

Overview

abstract

  • The treatment of complex parapneumonic effusions in children remains controversial, with some advocating less invasive, strictly medical management and others supporting a more aggressive approach of thoracotomy with or without decortication. Recent advances, including video-assisted thoracoscopic surgery and intrapleural fibrinolytic therapy, offer new options for effective treatment. We report the first case of successful resolution of a complex parapneumonic effusion in a 16-month-old girl with the use of tissue plasminogen activator (alteplase), infused via a catheter in the pleural space.

publication date

  • February 1, 2003

Research

keywords

  • Pleural Effusion
  • Pneumonia, Bacterial
  • Tissue Plasminogen Activator

Identity

Scopus Document Identifier

  • 17144434530

Digital Object Identifier (DOI)

  • 10.1542/peds.111.2.e188

PubMed ID

  • 12563094

Additional Document Info

volume

  • 111

issue

  • 2