A pediatric case of lymphomatoid granulomatosis with onset after completion of chemotherapy for acute myeloid leukemia. uri icon

Overview

abstract

  • In this case report, we present a pediatric case of lymphomatoid granulomatosis (LG) with onset just after the completion of chemotherapy for childhood acute myeloid leukemia (AML). After the completion of maintenance therapy, the patient was admitted to our clinic with a complaint of cough. Radiologic examinations revealed nodular lesions in lungs, liver, and kidney. His bone marrow was in remission. The histopathologic examination of the open lung biopsy was consistent with LG. He received only one cycle of cyclophosphamide and high-dose methyl prednisolone treatment and continued to receive interferon (IFN) alpha-2b therapy for 18 months. This treatment regimen resulted in an excellent response. In conclusion, LG may occur after the treatment of pediatric AML as a rare complication and IFN alpha-2b may be an effective treatment choice in these patients.

publication date

  • February 1, 2003

Research

keywords

  • Antineoplastic Combined Chemotherapy Protocols
  • Kidney Neoplasms
  • Leukemia, Myeloid
  • Liver Neoplasms
  • Lung Neoplasms
  • Lymphomatoid Granulomatosis

Identity

Scopus Document Identifier

  • 0037318624

Digital Object Identifier (DOI)

  • 10.1097/00043426-200302000-00016

PubMed ID

  • 12571471

Additional Document Info

volume

  • 25

issue

  • 2