21. Immunohematologic disorders. Review uri icon

Overview

abstract

  • Immunohematologic disorders are a broad group of entities in which hematologic diseases, usually cytopenias, are caused by immune reactions. These reactions lead to the development of hemolytic anemia, thrombocytopenia, or neutropenia, either separately or in combination. Common underlying mechanisms include immunodeficiency, systemic autoimmunity, and drug-induced reactions. Transplacental transfer of maternal alloantibodies can lead to fetal and neonatal cytopenias. Other immune reactions include antibodies to clotting factors, which result in both thrombosis and hemorrhage, and hemolytic and nonhemolytic reactions during transfusion of blood products.

publication date

  • February 1, 2003

Research

keywords

  • Hematologic Diseases
  • Immune System Diseases

Identity

Scopus Document Identifier

  • 0037323547

Digital Object Identifier (DOI)

  • 10.1067/mai.2003.157

PubMed ID

  • 12592312

Additional Document Info

volume

  • 111

issue

  • 2 Suppl