Intraoperative radiation therapy for breast cancer: technical notes. Academic Article uri icon

Overview

abstract

  • Interest in intraoperative radiation therapy (IORT) for breast cancer is increasing as the possible benefits of this technique for the patient become apparent. The rationale for the use of this segmental radiation therapy in place of whole-breast irradiation is based on the finding that approximately 85% of breast relapses are confined to the same quadrant of the breast as the primary tumor. Phase I and II trials have demonstrated no increase in postsurgical complication rates following the use of single-dose IORT in localized breast cancers. Longer follow-up is needed to assess the cosmetic outcome. Clinical trials to evaluate the effectiveness of IORT in the treatment of breast cancer are currently under way at the European Institute of Oncology (EIO) at the University of Milan, Italy, and at Memorial Sloan-Kettering Cancer Center (MSKCC) in New York. Here we report the two different techniques in use in these trials.

publication date

  • January 1, 2003

Research

keywords

  • Breast Neoplasms
  • Mastectomy, Segmental
  • Radiotherapy, High-Energy

Identity

Scopus Document Identifier

  • 0037490228

Digital Object Identifier (DOI)

  • 10.1046/j.1524-4741.2003.09208.x

PubMed ID

  • 12603383

Additional Document Info

volume

  • 9

issue

  • 2