Early vasoreactive profile of skeletonized versus pedicled internal thoracic artery grafts. Academic Article uri icon

Overview

abstract

  • BACKGROUND: No data are available on the early vasoreactive profile of skeletonized internal thoracic artery grafts. METHODS: Fifteen patients undergoing primary isolated coronary artery bypass grafting were randomly assigned to receive a skeletonized or pedicled internal thoracic artery graft. On the second postoperative day all patients were subjected to follow-up angiography and endovascular infusion of serotonin, acetylcholine, and isosorbide dinitrate. RESULTS: Internal thoracic artery grafts were widely patent in all cases. Mean diameters of the internal thoracic artery were 1.95 +/- 0.17 mm in the pedicled group and 2.26 +/- 0.40 mm in the skeletonized group. After serotonin challenge, mean internal thoracic artery diameters were reduced to 1.44 +/- 0.34 mm and 1.64 +/- 0.14 mm, respectively; acetylcholine challenge lead to a moderate degree of vasoconstriction (1.55 +/- 0.59 mm in the pedicled group and 1.84 +/- 0.15 mm in the skeletonized group). No statistically significant difference was evident between the two groups at any step. CONCLUSION: Skeletonization does not affect the early vasoreactive profile of internal thoracic artery grafts used for surgical myocardial revascularization.

authors

  • Gaudino, Mario Fl
  • Trani, Carlo
  • Glieca, Franco
  • Mazzari, Mario Attilio
  • Rigattieri, Stefano
  • Nasso, Giuseppe
  • Alessandrini, Francesco
  • Schiavoni, Giovanni
  • Possati, Gianfederico

publication date

  • March 1, 2003

Research

keywords

  • Dissection
  • Internal Mammary-Coronary Artery Anastomosis
  • Surgical Flaps
  • Thoracic Arteries
  • Tissue and Organ Harvesting
  • Vasoconstriction
  • Vasodilation

Identity

Scopus Document Identifier

  • 0037350232

Digital Object Identifier (DOI)

  • 10.1067/mtc.2003.106

PubMed ID

  • 12658207

Additional Document Info

volume

  • 125

issue

  • 3