Synaptogenesis and heritable aspects of executive attention. Review uri icon

Overview

abstract

  • In humans, changes in brain structure and function can be measured non-invasively during postnatal development. In animals, advanced optical imaging measures can track the formation of synapses during learning and behavior. With the recent progress in these technologies, it is appropriate to begin to assess how the physiological processes of synapse, circuit, and neural network formation relate to the process of cognitive development. Of particular interest is the development of executive function, which develops more gradually in humans. One approach that has shown promise is molecular genetics. The completion of the human genome project and the human genome diversity project make it straightforward to ask whether variation in a particular gene correlates with variation in behavior, brain structure, brain activity, or all of the above. Strategies that unify the wealth of biochemical knowledge pertaining to synapse formation with the functional measures of brain structure and activity may lead to new insights in developmental cognitive psychology.

publication date

  • January 1, 2003

Research

keywords

  • Attention
  • Cognition Disorders
  • Intellectual Disability
  • Synapses

Identity

Scopus Document Identifier

  • 0141633046

Digital Object Identifier (DOI)

  • 10.1002/mrdd.10078

PubMed ID

  • 12953297

Additional Document Info

volume

  • 9

issue

  • 3