Molluscum contagiosum in patients with human immunodeficiency virus infection. A review of twenty-seven patients. Academic Article uri icon

Overview

abstract

  • BACKGROUND: Molluscum contagiosum (MC) is a common and at times severely disfiguring cutaneous viral infection in patients with human immunodeficiency virus (HIV) infection. OBJECTIVE: The purpose of this study was to describe the clinical course of MC in patients with HIV infection and to examine the relation between presentation of MC and the stage of HIV infection, as measured by T-cell subsets. METHODS: This is a retrospective case study of 27 patients with MC and HIV infection who had T-cell subset determination within 60 days of diagnosis of MC. RESULTS: The overall mean CD4+ count, CD4+ percentage, and CD4+/CD8+ ratio were 85.7/mm3, 5.9%, and 0.10, respectively. An inverse relation between CD4+ count and the number of MC lesions was observed (p = 0.0023). Fourteen patients (52%) had facial and neck lesions alone, and seven (26%) had lesions in areas associated with sexual transmission. Pneumocystis carinii pneumonia had occurred in 8 patients (31%) and Kaposi's sarcoma in 15 patients (56%). CONCLUSION: MC can occur as a late manifestation of HIV infection and is a cutaneous correlate of cellular immune deficiency.

publication date

  • October 1, 1992

Research

keywords

  • AIDS-Related Opportunistic Infections
  • Molluscum Contagiosum

Identity

Scopus Document Identifier

  • 0026781432

Digital Object Identifier (DOI)

  • 10.1016/0190-9622(92)70226-6

PubMed ID

  • 1357010

Additional Document Info

volume

  • 27

issue

  • 4