Incorporation of vancomycin-supplemented bone incorporation of vancomycin-supplemented bone allografts: radiographical, histopathological and immunohistochemical study in pigs. Academic Article uri icon

Overview

abstract

  • We compared the incorporation of bone allografts with or without vancomycin in tibial defects of 18 pigs. High-quality radiographs, histological examination, immunological expression of metalloproteinase-13 (MMP-13) and transforming growth factor-beta 2 (TGFbeta2) indicated that there was no significant difference in bone allograft incorporation between up to 220 times the MIC (minimum inhibitory concentration) in bone allografts with 1 g of vancomycin in each 300 g of allograft or without this supplement.

publication date

  • October 1, 2003

Research

keywords

  • Anti-Bacterial Agents
  • Bone Transplantation
  • Vancomycin
  • Wound Healing

Identity

Scopus Document Identifier

  • 0142240275

Digital Object Identifier (DOI)

  • 10.1080/00016470310017884

PubMed ID

  • 14620969

Additional Document Info

volume

  • 74

issue

  • 5