Surgical resection and permanent brachytherapy for recurrent atypical and malignant meningioma. Academic Article uri icon

Overview

abstract

  • OBJECTIVE: Recurrent atypical and malignant meningiomas are difficult to treat successfully. Chemotherapy to date has been unsuccessful, and radiosurgery is limited to smaller tumors. Reoperation alone provides limited tumor control and limited prolonged survival. The addition of brachytherapy at the time of operation is an option. Here, we report the results of our series of patients with recurrent malignant meningioma treated with resection and brachytherapy with permanent low-dose (125)I. METHODS: The charts of patients in our database with recurrent atypical and malignant meningiomas treated by surgical resection and permanent (125)I brachytherapy at the University of California, San Francisco, between 1988 and 2002 were selected for this study. Calculations of disease-free survival and overall survival curves were made by the Kaplan-Meier actuarial method. Univariate analysis between Kaplan-Meier curves was based on the log-rank statistic, with a significance level set at a value of P

publication date

  • January 1, 2004

Research

keywords

  • Brachytherapy
  • Meningeal Neoplasms
  • Meningioma
  • Neoplasm Recurrence, Local

Identity

Scopus Document Identifier

  • 0348231910

Digital Object Identifier (DOI)

  • 10.1227/01.neu.0000097199.26412.2a

PubMed ID

  • 14683541

Additional Document Info

volume

  • 54

issue

  • 1