Involvement of interleukin-1 and the interleukin-1 receptor antagonist in in vitro embryo development among women undergoing in vitro fertilization-embryo transfer. Academic Article uri icon

Overview

abstract

  • PURPOSE: To examine the roles of Interleukin-1 (IL-1) and IL-1 receptor antagonist (IL-1ra), in in vitro embryo development and subsequent pregnancy outcome. METHODS: Maternal serum utilized to supplement embryo growth in IVF cycles was analyzed for the presence of IL-1 cytokines. RESULTS: The maternal serum that was utilized to supplement the embryo media was found to have measurable amounts of IL-1beta and IL-1ra. CONCLUSIONS: Relative antagonism of the IL-1 system was positively associated with embryo development and pregnancy outcome.

publication date

  • December 1, 2003

Research

keywords

  • Embryo Transfer
  • Fertilization in Vitro
  • Interleukin-1
  • Receptors, Interleukin-1

Identity

PubMed Central ID

  • PMC3455304

Scopus Document Identifier

  • 1542348360

Digital Object Identifier (DOI)

  • 10.1023/b:jarg.0000013650.76052.ae

PubMed ID

  • 15035549

Additional Document Info

volume

  • 20

issue

  • 12